Control of positive end-expiratory pressure (PEEP) for small animal ventilators

Detalhes bibliográficos
Autor(a) principal: Giannella-Neto, Antonio
Data de Publicação: 2010
Outros Autores: Ribeiro, Gabriel C. da Motta, Santos, Edil L., Soares, João H. N., Nunes, Marcelo V. Leão, Jandre, Frederico C.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/9473
Resumo: Universidade Federal do Rio de Janeiro. Instituto Alberto Luis Coimbra de Pós-Graduação e Pesquisa de Engenharia. Laboratório de Engenharia pulmonar. Programa de Engenharia Biomédica. Rio de Janeiro, RJ, Brasil.
id CRUZ_3000457a28e9048b3e334602bbc75bed
oai_identifier_str oai:www.arca.fiocruz.br:icict/9473
network_acronym_str CRUZ
network_name_str Repositório Institucional da FIOCRUZ (ARCA)
repository_id_str 2135
spelling Giannella-Neto, AntonioRibeiro, Gabriel C. da MottaSantos, Edil L.Soares, João H. N.Nunes, Marcelo V. LeãoJandre, Frederico C.2015-02-10T15:07:25Z2015-02-10T15:07:25Z2010GIANNELLA-NETO, Antonio. et al. Control of positive end-expiratory pressure (PEEP) for small animal ventilators. Biomed. eng. online., London, v . 9, n. 36, 2010.1475-925Xhttps://www.arca.fiocruz.br/handle/icict/9473engBioMed CentralControl of positive end-expiratory pressure (PEEP) for small animal ventilatorsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal do Rio de Janeiro. Instituto Alberto Luis Coimbra de Pós-Graduação e Pesquisa de Engenharia. Laboratório de Engenharia pulmonar. Programa de Engenharia Biomédica. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Instituto Alberto Luis Coimbra de Pós-Graduação e Pesquisa de Engenharia. Laboratório de Engenharia pulmonar. Programa de Engenharia Biomédica. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Instituto Alberto Luis Coimbra de Pós-Graduação e Pesquisa de Engenharia. Laboratório de Engenharia pulmonar. Programa de Engenharia Biomédica. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Instituto Alberto Luis Coimbra de Pós-Graduação e Pesquisa de Engenharia. Laboratório de Engenharia pulmonar. Programa de Engenharia Biomédica. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Instituto Alberto Luis Coimbra de Pós-Graduação e Pesquisa de Engenharia. Laboratório de Engenharia pulmonar. Programa de Engenharia Biomédica. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Instituto Alberto Luis Coimbra de Pós-Graduação e Pesquisa de Engenharia. Laboratório de Engenharia pulmonar. Programa de Engenharia Biomédica. Rio de Janeiro, RJ, Brasil.Background:The positive end-expiratory pressure (PEEP) for the mechanical ventilation of small animals is frequently obtained with water seals or by using ventilators developed for human use. An alternative mechanism is the use of an on-off expiratory valve closing at the moment when the alveolar pressure is equal to the target PEEP. In this paper, a novel PEEP controller (PEEP-new) and the PEEP system of a commercial small-animal ventilator, both based on switching an on-off valve, are evaluated. Methods:The proposed PEEP controller is a discrete integrator monitoring the error between the target PEEP and the airways opening pressure prior to the onset of an inspiratory cycle. In vitro as well as in vivo experiments with rats were carried out and the PEEP accuracy, settling time and under/overshoot were considered as a measure of performance. Results:The commercial PEEP controller did not pass the tests since it ignores the airways resistive pressure drop, resulting in a PEEP 5 cmH2 O greater than the target in most conditions. The PEEP-new presented steady-state errors smaller than 0.5 cmH2O, with settling times below 10 s and under/overshoot smaller than 2 cmH2 O. Conclusion:The PEEP-new presented acceptable performance, considering accuracy and temporal response. This novel PEEP generator may prove useful in many applications for small animal ventilators.AnimaisÁguainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://www.arca.fiocruz.br/bitstream/icict/9473/1/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD51ORIGINALControl of positive end-expiratory pressure (PEEP).pdfControl of positive end-expiratory pressure (PEEP).pdfapplication/pdf618207https://www.arca.fiocruz.br/bitstream/icict/9473/2/Control%20of%20positive%20end-expiratory%20pressure%20%28PEEP%29.pdf8d1b3ff625ff4b314787629e7e78ae52MD52TEXTControl of positive end-expiratory pressure (PEEP).pdf.txtControl of positive end-expiratory pressure (PEEP).pdf.txtExtracted texttext/plain27687https://www.arca.fiocruz.br/bitstream/icict/9473/3/Control%20of%20positive%20end-expiratory%20pressure%20%28PEEP%29.pdf.txtba61fa056a613dd4cb3d4790ea07fc99MD53icict/94732018-04-04 07:58:12.704oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352018-04-04T10:58:12Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Control of positive end-expiratory pressure (PEEP) for small animal ventilators
title Control of positive end-expiratory pressure (PEEP) for small animal ventilators
spellingShingle Control of positive end-expiratory pressure (PEEP) for small animal ventilators
Giannella-Neto, Antonio
Animais
Água
title_short Control of positive end-expiratory pressure (PEEP) for small animal ventilators
title_full Control of positive end-expiratory pressure (PEEP) for small animal ventilators
title_fullStr Control of positive end-expiratory pressure (PEEP) for small animal ventilators
title_full_unstemmed Control of positive end-expiratory pressure (PEEP) for small animal ventilators
title_sort Control of positive end-expiratory pressure (PEEP) for small animal ventilators
author Giannella-Neto, Antonio
author_facet Giannella-Neto, Antonio
Ribeiro, Gabriel C. da Motta
Santos, Edil L.
Soares, João H. N.
Nunes, Marcelo V. Leão
Jandre, Frederico C.
author_role author
author2 Ribeiro, Gabriel C. da Motta
Santos, Edil L.
Soares, João H. N.
Nunes, Marcelo V. Leão
Jandre, Frederico C.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Giannella-Neto, Antonio
Ribeiro, Gabriel C. da Motta
Santos, Edil L.
Soares, João H. N.
Nunes, Marcelo V. Leão
Jandre, Frederico C.
dc.subject.decs.pt_BR.fl_str_mv Animais
Água
topic Animais
Água
description Universidade Federal do Rio de Janeiro. Instituto Alberto Luis Coimbra de Pós-Graduação e Pesquisa de Engenharia. Laboratório de Engenharia pulmonar. Programa de Engenharia Biomédica. Rio de Janeiro, RJ, Brasil.
publishDate 2010
dc.date.issued.fl_str_mv 2010
dc.date.accessioned.fl_str_mv 2015-02-10T15:07:25Z
dc.date.available.fl_str_mv 2015-02-10T15:07:25Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv GIANNELLA-NETO, Antonio. et al. Control of positive end-expiratory pressure (PEEP) for small animal ventilators. Biomed. eng. online., London, v . 9, n. 36, 2010.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/9473
dc.identifier.issn.none.fl_str_mv 1475-925X
identifier_str_mv GIANNELLA-NETO, Antonio. et al. Control of positive end-expiratory pressure (PEEP) for small animal ventilators. Biomed. eng. online., London, v . 9, n. 36, 2010.
1475-925X
url https://www.arca.fiocruz.br/handle/icict/9473
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/9473/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/9473/2/Control%20of%20positive%20end-expiratory%20pressure%20%28PEEP%29.pdf
https://www.arca.fiocruz.br/bitstream/icict/9473/3/Control%20of%20positive%20end-expiratory%20pressure%20%28PEEP%29.pdf.txt
bitstream.checksum.fl_str_mv 7d48279ffeed55da8dfe2f8e81f3b81f
8d1b3ff625ff4b314787629e7e78ae52
ba61fa056a613dd4cb3d4790ea07fc99
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
_version_ 1813009241212977152

Registros relacionados