Association of Helicobacter pylori infection and giardiasis: results from a study of surrogate markers for fecal exposure among children.

Detalhes bibliográficos
Autor(a) principal: Moreira Júnior, Edson Duarte
Data de Publicação: 2005
Outros Autores: Nassri, Victor Bastos, Santos, Rafaela Sousa, Matos, Junísia Ferraz, Carvalho, Wilson Andrade de, Silvani, Célia Stolve, Sant’Ana, Círia Santana e
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/9827
Resumo: Fundação Irmã Dulce. Núcleo de Apoio à Pesquisa. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Hospital São Rafael, Salvador, BA, Brasil
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spelling Moreira Júnior, Edson DuarteNassri, Victor BastosSantos, Rafaela SousaMatos, Junísia FerrazCarvalho, Wilson Andrade deSilvani, Célia StolveSant’Ana, Círia Santana e2015-03-25T16:19:42Z2015-03-25T16:19:42Z2005MOREIRA JÚNIOR, E. D. et al. Association of Helicobacter pylori infection and giardiasis: results from a study of surrogate markers for fecal exposure among children. World Journal of Gastroenterology, v. 11, n. 18, p. 2759-2763 , 2005.1007-9327https://www.arca.fiocruz.br/handle/icict/9827engThe WJG Press and Elsevier Inc.Association of Helicobacter pylori infection and giardiasis: results from a study of surrogate markers for fecal exposure among children.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Irmã Dulce. Núcleo de Apoio à Pesquisa. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Hospital São Rafael, Salvador, BA, BrasilFundação Irmã Dulce. Núcleo de Apoio à Pesquisa. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Hospital São Rafael, Salvador, BA, BrasilFundação Irmã Dulce. Núcleo de Apoio à Pesquisa. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Hospital São Rafael, Salvador, BA, BrasilHospital São Rafael, Salvador, BA, BrasilHospital São Rafael, Salvador, BA, BrasilFundação Irmã Dulce. Núcleo de Apoio à Pesquisa. Salvador, BA, BrasilFundação Irmã Dulce. Núcleo de Apoio à Pesquisa. Salvador, BA, BrasilAIM: To investigate whether Helicobacter pylori (H pylori) infection is associated with hepatitis A virus (HAV) infection, presence of enteroparasites, and other surrogates of fecal exposure. METHODS: We conducted a cross-sectional study in 121 children consecutively admitted at a pediatric hospital in Salvador, Brazil. H pylori and HAV infection were identified by the presence of serum antibodies. Stool specimens were examined for the presence of ova and parasites. A structured questionnaire inquiring about sanitary conditions and life style was applied to each subject. RESULTS: Fifty-one of the 121 children (42.1%) were found to be seropositive for H pylori, and 45 (37.2%) for HAV. The seroprevalence of H pylori and HAV both increased significantly with age. Cross-tabulation of data showed that 26 (21.5%) were seropositive and 51 (42.1%) were negative for both H pylori and HAV antibodies (chi(2) = 7.18, OR = 2.8, CI 1.30-5.97). The age adjusted OR for an HAV-infected child being H pylori positive was 2.3 (CI 1.02-5.03). The agreement between H pylori and HAV seropositivity was fair (kappa = 0.24). After controlling for possible confounding, the variables remaining independently associated with seropositivity to H pylori were age, presence of Giardia lamblia in feces (OR = 3.2, 95%CI, 1.1-9.5) and poor garbage disposal quality (OR = 2.4, 95%CI, 1.1-5.1). CONCLUSION: Our data suggest that H pylori infection is associated with surrogate markers of fecal exposure. Thus, we conclude that the fecal-oral route is relevant in the transmission of HP among children in an urban setting of a developing country. The association observed between G. lamblia and H pylori infection may have several explanations. Further studies to investigate this relationship are warranted.H pyloriHepatitis A virusEpidemiologyTransmissionEnteroparasitesBrazilGiardíase/complicaçõesInfecções por Helicobacter/complicaçõesHelicobacter pyloriAnimaisBrasilCriançaPré-EscolarEstudos TransversaisPaíses em DesenvolvimentoFezes/parasitologiaFemininoGiardia lamblia/isolamento & purificaçãoInfecções por Helicobacter/transmissãoHumanosLactenteMasculinoPopulação Urbanainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82352https://www.arca.fiocruz.br/bitstream/icict/9827/1/license.txtafbdf7d7a9bcf771a1cc7edf5f618413MD51ORIGINALMoreira Jr ED Association.pdfMoreira Jr ED Association.pdfapplication/pdf368601https://www.arca.fiocruz.br/bitstream/icict/9827/2/Moreira%20Jr%20ED%20Association.pdfa30ac41f26baa5119d09c0ccef60b670MD52TEXTMoreira Jr ED Association.pdf.txtMoreira Jr ED Association.pdf.txtExtracted texttext/plain27489https://www.arca.fiocruz.br/bitstream/icict/9827/3/Moreira%20Jr%20ED%20Association.pdf.txte75da8ae8040b996e09a9a46e7cad083MD53icict/98272023-03-15 14:33:08.634oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:08Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Association of Helicobacter pylori infection and giardiasis: results from a study of surrogate markers for fecal exposure among children.
title Association of Helicobacter pylori infection and giardiasis: results from a study of surrogate markers for fecal exposure among children.
spellingShingle Association of Helicobacter pylori infection and giardiasis: results from a study of surrogate markers for fecal exposure among children.
Moreira Júnior, Edson Duarte
H pylori
Hepatitis A virus
Epidemiology
Transmission
Enteroparasites
Brazil
Giardíase/complicações
Infecções por Helicobacter/complicações
Helicobacter pylori
Animais
Brasil
Criança
Pré-Escolar
Estudos Transversais
Países em Desenvolvimento
Fezes/parasitologia
Feminino
Giardia lamblia/isolamento & purificação
Infecções por Helicobacter/transmissão
Humanos
Lactente
Masculino
População Urbana
title_short Association of Helicobacter pylori infection and giardiasis: results from a study of surrogate markers for fecal exposure among children.
title_full Association of Helicobacter pylori infection and giardiasis: results from a study of surrogate markers for fecal exposure among children.
title_fullStr Association of Helicobacter pylori infection and giardiasis: results from a study of surrogate markers for fecal exposure among children.
title_full_unstemmed Association of Helicobacter pylori infection and giardiasis: results from a study of surrogate markers for fecal exposure among children.
title_sort Association of Helicobacter pylori infection and giardiasis: results from a study of surrogate markers for fecal exposure among children.
author Moreira Júnior, Edson Duarte
author_facet Moreira Júnior, Edson Duarte
Nassri, Victor Bastos
Santos, Rafaela Sousa
Matos, Junísia Ferraz
Carvalho, Wilson Andrade de
Silvani, Célia Stolve
Sant’Ana, Círia Santana e
author_role author
author2 Nassri, Victor Bastos
Santos, Rafaela Sousa
Matos, Junísia Ferraz
Carvalho, Wilson Andrade de
Silvani, Célia Stolve
Sant’Ana, Círia Santana e
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Moreira Júnior, Edson Duarte
Nassri, Victor Bastos
Santos, Rafaela Sousa
Matos, Junísia Ferraz
Carvalho, Wilson Andrade de
Silvani, Célia Stolve
Sant’Ana, Círia Santana e
dc.subject.en.pt_BR.fl_str_mv H pylori
Hepatitis A virus
Epidemiology
Transmission
Enteroparasites
Brazil
topic H pylori
Hepatitis A virus
Epidemiology
Transmission
Enteroparasites
Brazil
Giardíase/complicações
Infecções por Helicobacter/complicações
Helicobacter pylori
Animais
Brasil
Criança
Pré-Escolar
Estudos Transversais
Países em Desenvolvimento
Fezes/parasitologia
Feminino
Giardia lamblia/isolamento & purificação
Infecções por Helicobacter/transmissão
Humanos
Lactente
Masculino
População Urbana
dc.subject.decs.pt_BR.fl_str_mv Giardíase/complicações
Infecções por Helicobacter/complicações
Helicobacter pylori
Animais
Brasil
Criança
Pré-Escolar
Estudos Transversais
Países em Desenvolvimento
Fezes/parasitologia
Feminino
Giardia lamblia/isolamento & purificação
Infecções por Helicobacter/transmissão
Humanos
Lactente
Masculino
População Urbana
description Fundação Irmã Dulce. Núcleo de Apoio à Pesquisa. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Hospital São Rafael, Salvador, BA, Brasil
publishDate 2005
dc.date.issued.fl_str_mv 2005
dc.date.accessioned.fl_str_mv 2015-03-25T16:19:42Z
dc.date.available.fl_str_mv 2015-03-25T16:19:42Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv MOREIRA JÚNIOR, E. D. et al. Association of Helicobacter pylori infection and giardiasis: results from a study of surrogate markers for fecal exposure among children. World Journal of Gastroenterology, v. 11, n. 18, p. 2759-2763 , 2005.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/9827
dc.identifier.issn.none.fl_str_mv 1007-9327
identifier_str_mv MOREIRA JÚNIOR, E. D. et al. Association of Helicobacter pylori infection and giardiasis: results from a study of surrogate markers for fecal exposure among children. World Journal of Gastroenterology, v. 11, n. 18, p. 2759-2763 , 2005.
1007-9327
url https://www.arca.fiocruz.br/handle/icict/9827
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv The WJG Press and Elsevier Inc.
publisher.none.fl_str_mv The WJG Press and Elsevier Inc.
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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https://www.arca.fiocruz.br/bitstream/icict/9827/2/Moreira%20Jr%20ED%20Association.pdf
https://www.arca.fiocruz.br/bitstream/icict/9827/3/Moreira%20Jr%20ED%20Association.pdf.txt
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
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