The correlation between obesity-related diseases and non-alcoholic fatty liver disease in women in the pre-operative evaluation for bariatric surgery assessed by transient hepatic elastography

Detalhes bibliográficos
Autor(a) principal: Barros, Fernando de
Data de Publicação: 2016
Outros Autores: Setúbal, Sérgio, Martinho, José Manoel, Leite, Nathalie Carvalho, Guaraná, Thais, Monteiro, Ana Beatriz Soares, Villela-Nogueira, Cristiane A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/32593
Resumo: 2020-04-15
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spelling Barros, Fernando deSetúbal, SérgioMartinho, José ManoelLeite, Nathalie CarvalhoGuaraná, ThaisMonteiro, Ana Beatriz SoaresVillela-Nogueira, Cristiane A.2019-04-18T14:11:32Z2019-04-18T14:11:32Z2016BARROS, Fernando de et al. The correlation between obesity-related diseases and non-alcoholic fatty liver disease in women in the pre-operative evaluation for bariatric surgery assessed by transient hepatic elastography. Obesity Surgery, v. 26, p. 2089-2097, 2016.0960-8923https://www.arca.fiocruz.br/handle/icict/3259310.1007/s11695-016-2054-y1708-0428engSpringer VerlagThe correlation between obesity-related diseases and non-alcoholic fatty liver disease in women in the pre-operative evaluation for bariatric surgery assessed by transient hepatic elastographyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2020-04-15Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Andaraí Federal Hospital. Rio de Janeiro, RJ, Brazil / Fluminense Federal University. Postgraduate Program. Niterói, RJ, Brazil.Fluminense Federal University. Postgraduate Program in Medical Sciences. Niterói, RJ, Brazil.Fluminense Federal University. Department of General Surgery. Niterói, RJ, Brazil.Rio de Janeiro Federal University. Internal Medicine Division. Rio de Janeiro, RJ, Brazil.Fluminense Federal University. Department of Gastroenterology. Niterói, RJ, Brazil.Fluminense Federal University. Department of Statistics. Niterói, RJ, Brazil.Rio de Janeiro Federal University. School of Medicine. Rio de Janeiro, RJ, Brazil.Background: Non-alcoholic fatty liver disease (NAFLD) is a common, severe disease in obese patients. However, NAFLD is usually underestimated by ultrasonography. Liver biopsy is not routinely done in bariatric surgery or during the follow-up. This study therefore examined the correlation between metabolic syndrome and NAFLD in morbidly obese patients based on an assessment using transient hepatic elastography (THE). Material and Methods: This study involved 50 female patients in the pre-operative phase for bariatric surgery. Before surgery, we collected clinical, laboratory, and anthropometric variables. THE measurements were obtained using a FibroScan® device (Echosens, Paris, France), and steatosis was quantified using Controlled Attenuation Parameter software (CAP). Statistical analyses were done using linear correlation and the Kruskal-Wallis test. Results: The mean of THE and CAP values were 7.56± 4.78 kPa and 279.94 ± 45.69 dB/m, respectively, and there was a significant linear correlation between the two measurements (r = 0.651; p< 0.001). The numbers of metabolic syndrome parameters did not influence the THE (p = 0.436) or CAP (p = 0.422) values. HbA1c and HOMA-IR showed a strong linear correlation with CAP (r= 0.643, p = 0.013 and r= 0.668, p = 0.009, respectively) and a tendency to some linear correlation with THE (r = 0.500, p = 0.05 and r = 0.500, p = 0.002, respectively). Conclusion: Morbidly obese women submitted to FibroScan® presented a high prevalence of severe steatosis and advanced fibrosis in our sample. Insulin resistance parameters were correlated with steatosis, but less with fibrosis.Bariatric surgeryFatty liverMetabolic syndrome XMorbid obesityNon-invasive testTransient elastographyinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83104https://www.arca.fiocruz.br/bitstream/icict/32593/1/license.txt79178e5f2a0eb066867a274556814938MD51ORIGINALve_Barros_Fernando_etal_INI_2016.pdfve_Barros_Fernando_etal_INI_2016.pdfapplication/pdf633092https://www.arca.fiocruz.br/bitstream/icict/32593/2/ve_Barros_Fernando_etal_INI_2016.pdf5965be94feb82e5be3c2ea305b5cbcf4MD52TEXTve_Barros_Fernando_etal_INI_2016.pdf.txtve_Barros_Fernando_etal_INI_2016.pdf.txtExtracted texttext/plain36643https://www.arca.fiocruz.br/bitstream/icict/32593/3/ve_Barros_Fernando_etal_INI_2016.pdf.txta69f0139b9b59ada095b256553a365bdMD53icict/325932021-03-24 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dc.title.pt_BR.fl_str_mv The correlation between obesity-related diseases and non-alcoholic fatty liver disease in women in the pre-operative evaluation for bariatric surgery assessed by transient hepatic elastography
title The correlation between obesity-related diseases and non-alcoholic fatty liver disease in women in the pre-operative evaluation for bariatric surgery assessed by transient hepatic elastography
spellingShingle The correlation between obesity-related diseases and non-alcoholic fatty liver disease in women in the pre-operative evaluation for bariatric surgery assessed by transient hepatic elastography
Barros, Fernando de
Bariatric surgery
Fatty liver
Metabolic syndrome X
Morbid obesity
Non-invasive test
Transient elastography
title_short The correlation between obesity-related diseases and non-alcoholic fatty liver disease in women in the pre-operative evaluation for bariatric surgery assessed by transient hepatic elastography
title_full The correlation between obesity-related diseases and non-alcoholic fatty liver disease in women in the pre-operative evaluation for bariatric surgery assessed by transient hepatic elastography
title_fullStr The correlation between obesity-related diseases and non-alcoholic fatty liver disease in women in the pre-operative evaluation for bariatric surgery assessed by transient hepatic elastography
title_full_unstemmed The correlation between obesity-related diseases and non-alcoholic fatty liver disease in women in the pre-operative evaluation for bariatric surgery assessed by transient hepatic elastography
title_sort The correlation between obesity-related diseases and non-alcoholic fatty liver disease in women in the pre-operative evaluation for bariatric surgery assessed by transient hepatic elastography
author Barros, Fernando de
author_facet Barros, Fernando de
Setúbal, Sérgio
Martinho, José Manoel
Leite, Nathalie Carvalho
Guaraná, Thais
Monteiro, Ana Beatriz Soares
Villela-Nogueira, Cristiane A.
author_role author
author2 Setúbal, Sérgio
Martinho, José Manoel
Leite, Nathalie Carvalho
Guaraná, Thais
Monteiro, Ana Beatriz Soares
Villela-Nogueira, Cristiane A.
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Barros, Fernando de
Setúbal, Sérgio
Martinho, José Manoel
Leite, Nathalie Carvalho
Guaraná, Thais
Monteiro, Ana Beatriz Soares
Villela-Nogueira, Cristiane A.
dc.subject.en.pt_BR.fl_str_mv Bariatric surgery
Fatty liver
Metabolic syndrome X
Morbid obesity
Non-invasive test
Transient elastography
topic Bariatric surgery
Fatty liver
Metabolic syndrome X
Morbid obesity
Non-invasive test
Transient elastography
description 2020-04-15
publishDate 2016
dc.date.issued.fl_str_mv 2016
dc.date.accessioned.fl_str_mv 2019-04-18T14:11:32Z
dc.date.available.fl_str_mv 2019-04-18T14:11:32Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv BARROS, Fernando de et al. The correlation between obesity-related diseases and non-alcoholic fatty liver disease in women in the pre-operative evaluation for bariatric surgery assessed by transient hepatic elastography. Obesity Surgery, v. 26, p. 2089-2097, 2016.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/32593
dc.identifier.issn.pt_BR.fl_str_mv 0960-8923
dc.identifier.doi.none.fl_str_mv 10.1007/s11695-016-2054-y
dc.identifier.eissn.none.fl_str_mv 1708-0428
identifier_str_mv BARROS, Fernando de et al. The correlation between obesity-related diseases and non-alcoholic fatty liver disease in women in the pre-operative evaluation for bariatric surgery assessed by transient hepatic elastography. Obesity Surgery, v. 26, p. 2089-2097, 2016.
0960-8923
10.1007/s11695-016-2054-y
1708-0428
url https://www.arca.fiocruz.br/handle/icict/32593
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Springer Verlag
publisher.none.fl_str_mv Springer Verlag
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/32593/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/32593/2/ve_Barros_Fernando_etal_INI_2016.pdf
https://www.arca.fiocruz.br/bitstream/icict/32593/3/ve_Barros_Fernando_etal_INI_2016.pdf.txt
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