Inhibitory effect of cyclophosphamide on the biosynthesis of a perchloro-soluble protein fraction of ehrlich ascites carcinoma cells

Detalhes bibliográficos
Autor(a) principal: Abreu, R. Raposo
Data de Publicação: 1973
Outros Autores: Abreu, Luiz A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/41865
Resumo: Foi determinada a fração mucoproteica percloro-solúvel nas células do carcinoma ascítico de Ehrlich, no 10º e 12º dias após a inoculação do tumor. Nos camundongos injetados com uma única dose subcutânea de ciclofosfamida (200 mg/kg) os níveis desta fração foram encontrados consideravelmente mais baixos. A análise estatística demonstrou que as diferenças observadas entre os animais controles e os tratados com ciclofosfamida foram altamente significativas.
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spelling Abreu, R. RaposoAbreu, Luiz A.2020-06-24T20:05:33Z2020-06-24T20:05:33Z1973ABREU, R. Raposo; ABREU,Luiz A. Inhibitory effect of cyclophosphamide on the biosynthesis of a perchloro-soluble protein fraction of ehrlich ascites carcinoma cells. Memórias do Instituto Oswaldo Cruz, v. 71, n. 4, p. 439-442, 1973.0074-0276https://www.arca.fiocruz.br/handle/icict/4186510.1590/S0074-027619730003000071678-8060Foi determinada a fração mucoproteica percloro-solúvel nas células do carcinoma ascítico de Ehrlich, no 10º e 12º dias após a inoculação do tumor. Nos camundongos injetados com uma única dose subcutânea de ciclofosfamida (200 mg/kg) os níveis desta fração foram encontrados consideravelmente mais baixos. A análise estatística demonstrou que as diferenças observadas entre os animais controles e os tratados com ciclofosfamida foram altamente significativas.The perchloro-soluble mucroptotein fraction was determined in the cells of Ehrlich ascites carcinoma on the 10th and 12th days post-inoculation of the tumor. After 3 days of a single subcutaneous dose of cyclophosphamide (200 mg/kg) the mucoprotein levels were found considerable lower. This difference was highly significant statistically.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, GB, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, GB, Brasil.engFundação Oswaldo Cruz. Instituto Oswaldo Cruz.Carcinoma ascítico de EhrliFração mucoproteica percloro-solúvelCiclofosfamidaCyclophosphamideCyclophosphamideEhrlich ascites carcinomaPerchloro-soluble mucroptotein fractionInhibitory effect of cyclophosphamide on the biosynthesis of a perchloro-soluble protein fraction of ehrlich ascites carcinoma cellsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/41865/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALRRaposoAbreu_etal_IOC_1973.pdfRRaposoAbreu_etal_IOC_1973.pdfapplication/pdf257633https://www.arca.fiocruz.br/bitstream/icict/41865/2/RRaposoAbreu_etal_IOC_1973.pdfda7ac9093e059caf72df1bd0b023f638MD52TEXTRRaposoAbreu_etal_IOC_1973.pdf.txtRRaposoAbreu_etal_IOC_1973.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Inhibitory effect of cyclophosphamide on the biosynthesis of a perchloro-soluble protein fraction of ehrlich ascites carcinoma cells
title Inhibitory effect of cyclophosphamide on the biosynthesis of a perchloro-soluble protein fraction of ehrlich ascites carcinoma cells
spellingShingle Inhibitory effect of cyclophosphamide on the biosynthesis of a perchloro-soluble protein fraction of ehrlich ascites carcinoma cells
Abreu, R. Raposo
Carcinoma ascítico de Ehrli
Fração mucoproteica percloro-solúvel
Ciclofosfamida
Cyclophosphamide
Cyclophosphamide
Ehrlich ascites carcinoma
Perchloro-soluble mucroptotein fraction
title_short Inhibitory effect of cyclophosphamide on the biosynthesis of a perchloro-soluble protein fraction of ehrlich ascites carcinoma cells
title_full Inhibitory effect of cyclophosphamide on the biosynthesis of a perchloro-soluble protein fraction of ehrlich ascites carcinoma cells
title_fullStr Inhibitory effect of cyclophosphamide on the biosynthesis of a perchloro-soluble protein fraction of ehrlich ascites carcinoma cells
title_full_unstemmed Inhibitory effect of cyclophosphamide on the biosynthesis of a perchloro-soluble protein fraction of ehrlich ascites carcinoma cells
title_sort Inhibitory effect of cyclophosphamide on the biosynthesis of a perchloro-soluble protein fraction of ehrlich ascites carcinoma cells
author Abreu, R. Raposo
author_facet Abreu, R. Raposo
Abreu, Luiz A.
author_role author
author2 Abreu, Luiz A.
author2_role author
dc.contributor.author.fl_str_mv Abreu, R. Raposo
Abreu, Luiz A.
dc.subject.other.pt_BR.fl_str_mv Carcinoma ascítico de Ehrli
Fração mucoproteica percloro-solúvel
Ciclofosfamida
topic Carcinoma ascítico de Ehrli
Fração mucoproteica percloro-solúvel
Ciclofosfamida
Cyclophosphamide
Cyclophosphamide
Ehrlich ascites carcinoma
Perchloro-soluble mucroptotein fraction
dc.subject.en.pt_BR.fl_str_mv Cyclophosphamide
Cyclophosphamide
Ehrlich ascites carcinoma
Perchloro-soluble mucroptotein fraction
description Foi determinada a fração mucoproteica percloro-solúvel nas células do carcinoma ascítico de Ehrlich, no 10º e 12º dias após a inoculação do tumor. Nos camundongos injetados com uma única dose subcutânea de ciclofosfamida (200 mg/kg) os níveis desta fração foram encontrados consideravelmente mais baixos. A análise estatística demonstrou que as diferenças observadas entre os animais controles e os tratados com ciclofosfamida foram altamente significativas.
publishDate 1973
dc.date.issued.fl_str_mv 1973
dc.date.accessioned.fl_str_mv 2020-06-24T20:05:33Z
dc.date.available.fl_str_mv 2020-06-24T20:05:33Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv ABREU, R. Raposo; ABREU,Luiz A. Inhibitory effect of cyclophosphamide on the biosynthesis of a perchloro-soluble protein fraction of ehrlich ascites carcinoma cells. Memórias do Instituto Oswaldo Cruz, v. 71, n. 4, p. 439-442, 1973.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/41865
dc.identifier.issn.pt_BR.fl_str_mv 0074-0276
dc.identifier.doi.none.fl_str_mv 10.1590/S0074-02761973000300007
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv ABREU, R. Raposo; ABREU,Luiz A. Inhibitory effect of cyclophosphamide on the biosynthesis of a perchloro-soluble protein fraction of ehrlich ascites carcinoma cells. Memórias do Instituto Oswaldo Cruz, v. 71, n. 4, p. 439-442, 1973.
0074-0276
10.1590/S0074-02761973000300007
1678-8060
url https://www.arca.fiocruz.br/handle/icict/41865
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
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