Current and Future Trends in the Clinical Diagnosis of Rickettsioses Sensu Lato

Detalhes bibliográficos
Autor(a) principal: Missailidis, S
Data de Publicação: 2014
Outros Autores: Godoy, D. T, Mares-Guia, M. A. M. M, Favacho, A. R. M, Lemos, E. R. S
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/10474
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil. Laboratório de Hantaviroses e Rickettsioses. Rio de Janeiro, RJ, Brasil.
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spelling Missailidis, SGodoy, D. TMares-Guia, M. A. M. MFavacho, A. R. MLemos, E. R. S2015-05-22T18:42:44Z2015-05-22T18:42:44Z2014MISSAILIDIS, S. et al. Current and Future Trends in the Clinical Diagnosis of Rickettsioses Sensu Lato. International Journal of Tropical Diseases & Health, v.4, n.2, p.147-181, 2014.2278 – 1005https://www.arca.fiocruz.br/handle/icict/10474engScienceDomain InternationalCurrent and Future Trends in the Clinical Diagnosis of Rickettsioses Sensu Latoinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil. Laboratório de Hantaviroses e Rickettsioses. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil. Laboratório de Hantaviroses e Rickettsioses. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil. Laboratório de Hantaviroses e Rickettsioses. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil. Laboratório de Hantaviroses e Rickettsioses. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil. Laboratório de Hantaviroses e Rickettsioses. Rio de Janeiro, RJ, Brasil.Aims: The aim of this review is to present Rickettsioses sensu lato, with emphasis on their current and future clinical diagnosis. The review presents the conditions, the agents that cause them, and the current gold standards on their diagnosis in national and international reference centres. Additionally, this review covers the various emerging technologies available in the diagnosis of Rickettsioses and discusses their potential for future use as gold standards in the diagnosis of these diseases. Introduction: The introduction presents Rickettsioses sensu lato and gives a broad overview of the conditions they cause, the issues associated with their current diagnosis and the need for their improved, earlier and more accurate diagnosis, in order to prevent current issues with false negatives, misdiagnosis or delay in the diagnosis associated with these conditions, which often renders them grave or lethal. Main Body: The main body of the review presents in independent sections Rickettsias, Ehrlichia, Anaplasma, Bartonella and Coxiella and the conditions associated with each of these bacteria. Spotted fever, endemic typhus, human granulocytic anaplasmosis, human monocytic ehrlichioses, bartonellosis and Q-fever are some of the conditions associated with this group of proteobacteria. The emphasis is on the clinical diagnosis of these conditions and an overview of the current practice, gold standards in reference laboratories and improvements in these methodologies is presented. The last part of the review focuses on novel technologies in bacterial detection and their application specifically on Rickettsioses sensu lato, demonstrating how these technologies are being applied in this field and how they could improve current standards and resolve issues associated with the clinical diagnosis of rickettsioses. Conclusion: Rickettsioses sensu lato are conditions associated with proteobacteria historically included in the Rickettsiaceae family, able to cause a number of conditions, often grave or lethal. One of the major issues associated with poor clinical outcome is the lack of early and accurate differential diagnostic methodologies. Current methods, including serological and molecular biology techniques have various advantages and disadvantages, which new technologies available or currently in development may be in a position to resolve and the issues associated with the institution of such technologies. - See more at: http://www.sciencedomain.org/abstract.php?iid=321&id=19&aid=2572#sthash.iG6Phb0Q.dpufRickettsiaEhrlichiaAnaplasmaBartonellaCoxiellaClinical diagnosisRickettsiaAnaplasmaBartonellaDiagnóstico Clínicoinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1914https://www.arca.fiocruz.br/bitstream/icict/10474/1/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD51ORIGINALdt_godoyetal_IOC_2014.pdfapplication/pdf314678https://www.arca.fiocruz.br/bitstream/icict/10474/2/dt_godoyetal_IOC_2014.pdf6b154cdce25b36e9882c1f65a411dc6aMD52TEXTdt_godoyetal_IOC_2014.pdf.txtdt_godoyetal_IOC_2014.pdf.txtExtracted texttext/plain131254https://www.arca.fiocruz.br/bitstream/icict/10474/3/dt_godoyetal_IOC_2014.pdf.txt21337e9cc98dbe3ec9d0ccde5dc47bb5MD53icict/104742023-09-05 10:22:57.099oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-09-05T13:22:57Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Current and Future Trends in the Clinical Diagnosis of Rickettsioses Sensu Lato
title Current and Future Trends in the Clinical Diagnosis of Rickettsioses Sensu Lato
spellingShingle Current and Future Trends in the Clinical Diagnosis of Rickettsioses Sensu Lato
Missailidis, S
Rickettsia
Ehrlichia
Anaplasma
Bartonella
Coxiella
Clinical diagnosis
Rickettsia
Anaplasma
Bartonella
Diagnóstico Clínico
title_short Current and Future Trends in the Clinical Diagnosis of Rickettsioses Sensu Lato
title_full Current and Future Trends in the Clinical Diagnosis of Rickettsioses Sensu Lato
title_fullStr Current and Future Trends in the Clinical Diagnosis of Rickettsioses Sensu Lato
title_full_unstemmed Current and Future Trends in the Clinical Diagnosis of Rickettsioses Sensu Lato
title_sort Current and Future Trends in the Clinical Diagnosis of Rickettsioses Sensu Lato
author Missailidis, S
author_facet Missailidis, S
Godoy, D. T
Mares-Guia, M. A. M. M
Favacho, A. R. M
Lemos, E. R. S
author_role author
author2 Godoy, D. T
Mares-Guia, M. A. M. M
Favacho, A. R. M
Lemos, E. R. S
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Missailidis, S
Godoy, D. T
Mares-Guia, M. A. M. M
Favacho, A. R. M
Lemos, E. R. S
dc.subject.en.pt_BR.fl_str_mv Rickettsia
Ehrlichia
Anaplasma
Bartonella
Coxiella
Clinical diagnosis
topic Rickettsia
Ehrlichia
Anaplasma
Bartonella
Coxiella
Clinical diagnosis
Rickettsia
Anaplasma
Bartonella
Diagnóstico Clínico
dc.subject.decs.pt_BR.fl_str_mv Rickettsia
Anaplasma
Bartonella
Diagnóstico Clínico
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil. Laboratório de Hantaviroses e Rickettsioses. Rio de Janeiro, RJ, Brasil.
publishDate 2014
dc.date.issued.fl_str_mv 2014
dc.date.accessioned.fl_str_mv 2015-05-22T18:42:44Z
dc.date.available.fl_str_mv 2015-05-22T18:42:44Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv MISSAILIDIS, S. et al. Current and Future Trends in the Clinical Diagnosis of Rickettsioses Sensu Lato. International Journal of Tropical Diseases & Health, v.4, n.2, p.147-181, 2014.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/10474
dc.identifier.issn.pt_BR.fl_str_mv 2278 – 1005
identifier_str_mv MISSAILIDIS, S. et al. Current and Future Trends in the Clinical Diagnosis of Rickettsioses Sensu Lato. International Journal of Tropical Diseases & Health, v.4, n.2, p.147-181, 2014.
2278 – 1005
url https://www.arca.fiocruz.br/handle/icict/10474
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv ScienceDomain International
publisher.none.fl_str_mv ScienceDomain International
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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