Determination of hepatitis B, C and D prevalence among urban and Amerindian populations from the Eastern Brazilian Amazon: a cross sectional study
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2018 |
| Outros Autores: | , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/29157 |
Resumo: | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil. |
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Villar, Livia MeloMilagres, Flavio Augusto PáduaLampe, ElisabethCruz, Helena MedinaScalioni, Leticia de PaulaMagalhães, Mônica de Avelar Figueiredo MafraRomão, Anselmo RochaCarrijo, Renata de Saldanha da Gama GraciePaula, Vanessa Salete de2018-09-30T15:31:58Z2018-09-30T15:31:58Z2018VILLAR, Livia Melo et al. Determination of hepatitis B, C and D prevalence among urban and Amerindian populations from the Eastern Brazilian Amazon: a cross sectional study. BMC Infectious Diseases, v. 18, n. 411, p. 1-9, 2018.1471-2334https://www.arca.fiocruz.br/handle/icict/2915710.1186/s12879-018-3279-2engBMCHepatite BHepatite CHepatite DprevalênciaAmeríndiosNorte de BrasilAmazônia OrientalHepatitis BHepatitis CHepatitis DprevalenceAmerindiansEastern AmazonNorth BrazilDetermination of hepatitis B, C and D prevalence among urban and Amerindian populations from the Eastern Brazilian Amazon: a cross sectional studyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil.Universidade Federal do Tocantins. PO, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Comunicação e Informação Científica e Tecnológica em Saùde. Laboratório de Informação em Saúde. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Comunicação e Informação Científica e Tecnológica em Saùde. Laboratório de Informação em Saúde. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Comunicação e Informação Científica e Tecnológica em Saùde. Laboratório de Informação em Saúde. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Molecular. Rio de Janeiro, RJ, Brasil.Background: This study was conducted to determine the prevalence of HBV, HCV, and HDV in urban populations and Amerindians living in the state of Tocantins (Eastern Amazon). Methods: A total of 948 individuals were recruited in Tocantinopolis city (Tocantins state) of whom 603 were Amerindians (from 6 tribes) and 345 were non-Amerindians (6 urban areas of Tocantinópolis city). Anti-HCV, HBsAg, antiHBc, anti-HBs, anti-HBc IgM, anti-HBe, HBeAg, and anti-delta antibodies were determined using enzyme immunoassay. Results: HBV cleared infection (both anti-HBc/anti-HBs+), chronic inactive/immune controlled HBV infection (anti-HBc + only), previous HBV vaccination (anti-HBs + only), active HBV infection (HBsAg+), individuals susceptible to HBV, and anti-HCV reactivity were found in 12.9, 1.8, 27.2, 0.5, 57.7, 1.2% in Amerindians and 12.1, 2.0, 37.1, 0.3, 55.4, 0.3% in nonAmerindians respectively. Out of 139 anti-HBc reactive individuals, 70 were anti-HBe reactive and none presented HBeAg or anti-HBc IgM. Anti-HBc prevalence was associated to older age (p < 0.0001). Overall anti-Delta prevalence was 0.3% and regarding anti-HBc reactive individuals, anti-delta prevalence was 3.4 and 0% in Amerindians and nonAmerindians respectively. Conclusions: Overall low prevalence of HBV and HCV infection was found in the populations studied, but high HBV and HCV prevalence was observed in Amerindians compared to non-Amerindians suggesting that these individuals have a higher likelihood of acquiring to these infections. Anti-delta antibodies were found among Amerindians from Eastern Amazon suggesting a risk for this population. Of note is that nearly half of Amerindians had no anti-HBs, indicating a need for HBV vaccination campaigns in this population.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/29157/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALhelenamedina_cruz_etal_IOC_2018.pdfhelenamedina_cruz_etal_IOC_2018.pdfapplication/pdf1362822https://www.arca.fiocruz.br/bitstream/icict/29157/2/helenamedina_cruz_etal_IOC_2018.pdf66ea7a0bf448c9666834193a32e43dd8MD52TEXThelenamedina_cruz_etal_IOC_2018.pdf.txthelenamedina_cruz_etal_IOC_2018.pdf.txtExtracted texttext/plain33466https://www.arca.fiocruz.br/bitstream/icict/29157/3/helenamedina_cruz_etal_IOC_2018.pdf.txt9bb7aeea0c1d68ff77e489432f301d12MD53icict/291572020-06-04 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| dc.title.pt_BR.fl_str_mv |
Determination of hepatitis B, C and D prevalence among urban and Amerindian populations from the Eastern Brazilian Amazon: a cross sectional study |
| title |
Determination of hepatitis B, C and D prevalence among urban and Amerindian populations from the Eastern Brazilian Amazon: a cross sectional study |
| spellingShingle |
Determination of hepatitis B, C and D prevalence among urban and Amerindian populations from the Eastern Brazilian Amazon: a cross sectional study Villar, Livia Melo Hepatite B Hepatite C Hepatite D prevalência Ameríndios Norte de Brasil Amazônia Oriental Hepatitis B Hepatitis C Hepatitis D prevalence Amerindians Eastern Amazon North Brazil |
| title_short |
Determination of hepatitis B, C and D prevalence among urban and Amerindian populations from the Eastern Brazilian Amazon: a cross sectional study |
| title_full |
Determination of hepatitis B, C and D prevalence among urban and Amerindian populations from the Eastern Brazilian Amazon: a cross sectional study |
| title_fullStr |
Determination of hepatitis B, C and D prevalence among urban and Amerindian populations from the Eastern Brazilian Amazon: a cross sectional study |
| title_full_unstemmed |
Determination of hepatitis B, C and D prevalence among urban and Amerindian populations from the Eastern Brazilian Amazon: a cross sectional study |
| title_sort |
Determination of hepatitis B, C and D prevalence among urban and Amerindian populations from the Eastern Brazilian Amazon: a cross sectional study |
| author |
Villar, Livia Melo |
| author_facet |
Villar, Livia Melo Milagres, Flavio Augusto Pádua Lampe, Elisabeth Cruz, Helena Medina Scalioni, Leticia de Paula Magalhães, Mônica de Avelar Figueiredo Mafra Romão, Anselmo Rocha Carrijo, Renata de Saldanha da Gama Gracie Paula, Vanessa Salete de |
| author_role |
author |
| author2 |
Milagres, Flavio Augusto Pádua Lampe, Elisabeth Cruz, Helena Medina Scalioni, Leticia de Paula Magalhães, Mônica de Avelar Figueiredo Mafra Romão, Anselmo Rocha Carrijo, Renata de Saldanha da Gama Gracie Paula, Vanessa Salete de |
| author2_role |
author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Villar, Livia Melo Milagres, Flavio Augusto Pádua Lampe, Elisabeth Cruz, Helena Medina Scalioni, Leticia de Paula Magalhães, Mônica de Avelar Figueiredo Mafra Romão, Anselmo Rocha Carrijo, Renata de Saldanha da Gama Gracie Paula, Vanessa Salete de |
| dc.subject.other.pt_BR.fl_str_mv |
Hepatite B Hepatite C Hepatite D prevalência Ameríndios Norte de Brasil Amazônia Oriental |
| topic |
Hepatite B Hepatite C Hepatite D prevalência Ameríndios Norte de Brasil Amazônia Oriental Hepatitis B Hepatitis C Hepatitis D prevalence Amerindians Eastern Amazon North Brazil |
| dc.subject.en.pt_BR.fl_str_mv |
Hepatitis B Hepatitis C Hepatitis D prevalence Amerindians Eastern Amazon North Brazil |
| description |
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil. |
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2018 |
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2018-09-30T15:31:58Z |
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2018-09-30T15:31:58Z |
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2018 |
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info:eu-repo/semantics/article |
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publishedVersion |
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VILLAR, Livia Melo et al. Determination of hepatitis B, C and D prevalence among urban and Amerindian populations from the Eastern Brazilian Amazon: a cross sectional study. BMC Infectious Diseases, v. 18, n. 411, p. 1-9, 2018. |
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https://www.arca.fiocruz.br/handle/icict/29157 |
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1471-2334 |
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10.1186/s12879-018-3279-2 |
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VILLAR, Livia Melo et al. Determination of hepatitis B, C and D prevalence among urban and Amerindian populations from the Eastern Brazilian Amazon: a cross sectional study. BMC Infectious Diseases, v. 18, n. 411, p. 1-9, 2018. 1471-2334 10.1186/s12879-018-3279-2 |
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