SARS-CoV-2 Infection in Pregnant Women: Neuroimmune-Endocrine Changes at the Maternal-Fetal Interface

Detalhes bibliográficos
Autor(a) principal: Granja, Marcelo Gomes
Data de Publicação: 2021
Outros Autores: Oliveira, Amanda Candida da Rocha, Figueiredo, Camila Saggioro de, Gomes, Alex Portes, Ferreira, Erica Camila, Araujo, Elizabeth Giestal de, Faria Neto, Hugo Caire de Castro
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/47365
Resumo: Universidade Federal do Estado do Rio de Janeiro - UNIRIO. Programa de Biologia Celular e Molecular. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ, Brasil.
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spelling Granja, Marcelo GomesOliveira, Amanda Candida da RochaFigueiredo, Camila Saggioro deGomes, Alex PortesFerreira, Erica CamilaAraujo, Elizabeth Giestal deFaria Neto, Hugo Caire de Castro2021-05-25T18:49:03Z2021-05-25T18:49:03Z2021GRANJA, Marcelo Gomes et al. SARS-CoV-2 Infection in Pregnant Women: Neuroimmune-Endocrine Changes at the Maternal-Fetal Interface. Neuroimmunomodulation, v. 28, 32p, Apr. 20211021-7401https://www.arca.fiocruz.br/handle/icict/4736510.1159/000515556engKarger PublishersDoença do coronavírus 2019Coronavírus 2 relacionado à síndrome respiratória aguda graveGravidezNeurodevelopmentInterface materno-fetalInterações neuroimunesCoronavirus disease 2019Severe acute respiratory syndrome-related coronavirus 2PregnancyNeurodevelopmentMaternal-fetal interfaceNeuroimmune interactionsSARS-CoV-2 Infection in Pregnant Women: Neuroimmune-Endocrine Changes at the Maternal-Fetal Interfaceinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal do Estado do Rio de Janeiro - UNIRIO. Programa de Biologia Celular e Molecular. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ, Brasil.Universidade Federal Fluminense. Programa de Neurociência. Niterói, RJ, Brasil.Universidade Federal Fluminense. Programa de Neurociência. Niterói, RJ, Brasil.Universidade Federal Fluminense. Programa de Ciências Médicas, Neurologia e Neurociências. Niterói, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ, Brasil.Universidade Federal Fluminense. Programa de Neurociência. Niterói, RJ, Brasil / Instituto Nacional de Tecnologia-Neuroimunomodulação-INCT-NIM. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ, Brasil / Instituto Nacional de Tecnologia-Neuroimunomodulação-INCT-NIM. Rio de Janeiro, RJ, Brasil.Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome-related coronavirus 2 (SARS CoV-2) has devastating effects on the population worldwide. Given this scenario, the extent of the impact of the disease on more vulnerable individuals, such as pregnant women, is of great concern. Although pregnancy may be a risk factor in respiratory virus infections, there are no considerable differ ences regarding COVID-19 severity observed between preg nant and nonpregnant women. In these circumstances, an emergent concern is the possibility of neurodevelopmental and neuropsychiatric harm for the offspring of infected mothers. Currently, there is no stronger evidence indicating vertical transmission of SARS-CoV-2; however, the exacer bated inflammatory response observed in the disease could lead to several impairments in the offspring’s brain. Further more, in the face of historical knowledge on possible long term consequences for the progeny’s brain after infection by viruses, we must consider that this might be another delete rious facet of COVID-19. In light of neuroimmune interac tions at the maternal-fetal interface, we review here the pos sible harmful outcomes to the offspring brains of mothers infected by SARS-CoV-2.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/47365/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALHugoCC_FariaNeto_etal_IOC_2021.pdfHugoCC_FariaNeto_etal_IOC_2021.pdfapplication/pdf1538697https://www.arca.fiocruz.br/bitstream/icict/47365/2/HugoCC_FariaNeto_etal_IOC_2021.pdfe7baf59c56b2bd82be076a86a4a7f978MD52TEXTHugoCC_FariaNeto_etal_IOC_2021.pdf.txtHugoCC_FariaNeto_etal_IOC_2021.pdf.txtExtracted texttext/plain122626https://www.arca.fiocruz.br/bitstream/icict/47365/3/HugoCC_FariaNeto_etal_IOC_2021.pdf.txt2ecc60a03c27e03778fb88c5330d4a36MD53icict/473652021-05-26 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dc.title.pt_BR.fl_str_mv SARS-CoV-2 Infection in Pregnant Women: Neuroimmune-Endocrine Changes at the Maternal-Fetal Interface
title SARS-CoV-2 Infection in Pregnant Women: Neuroimmune-Endocrine Changes at the Maternal-Fetal Interface
spellingShingle SARS-CoV-2 Infection in Pregnant Women: Neuroimmune-Endocrine Changes at the Maternal-Fetal Interface
Granja, Marcelo Gomes
Doença do coronavírus 2019
Coronavírus 2 relacionado à síndrome respiratória aguda grave
Gravidez
Neurodevelopment
Interface materno-fetal
Interações neuroimunes
Coronavirus disease 2019
Severe acute respiratory syndrome-related coronavirus 2
Pregnancy
Neurodevelopment
Maternal-fetal interface
Neuroimmune interactions
title_short SARS-CoV-2 Infection in Pregnant Women: Neuroimmune-Endocrine Changes at the Maternal-Fetal Interface
title_full SARS-CoV-2 Infection in Pregnant Women: Neuroimmune-Endocrine Changes at the Maternal-Fetal Interface
title_fullStr SARS-CoV-2 Infection in Pregnant Women: Neuroimmune-Endocrine Changes at the Maternal-Fetal Interface
title_full_unstemmed SARS-CoV-2 Infection in Pregnant Women: Neuroimmune-Endocrine Changes at the Maternal-Fetal Interface
title_sort SARS-CoV-2 Infection in Pregnant Women: Neuroimmune-Endocrine Changes at the Maternal-Fetal Interface
author Granja, Marcelo Gomes
author_facet Granja, Marcelo Gomes
Oliveira, Amanda Candida da Rocha
Figueiredo, Camila Saggioro de
Gomes, Alex Portes
Ferreira, Erica Camila
Araujo, Elizabeth Giestal de
Faria Neto, Hugo Caire de Castro
author_role author
author2 Oliveira, Amanda Candida da Rocha
Figueiredo, Camila Saggioro de
Gomes, Alex Portes
Ferreira, Erica Camila
Araujo, Elizabeth Giestal de
Faria Neto, Hugo Caire de Castro
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Granja, Marcelo Gomes
Oliveira, Amanda Candida da Rocha
Figueiredo, Camila Saggioro de
Gomes, Alex Portes
Ferreira, Erica Camila
Araujo, Elizabeth Giestal de
Faria Neto, Hugo Caire de Castro
dc.subject.other.pt_BR.fl_str_mv Doença do coronavírus 2019
Coronavírus 2 relacionado à síndrome respiratória aguda grave
Gravidez
Neurodevelopment
Interface materno-fetal
Interações neuroimunes
topic Doença do coronavírus 2019
Coronavírus 2 relacionado à síndrome respiratória aguda grave
Gravidez
Neurodevelopment
Interface materno-fetal
Interações neuroimunes
Coronavirus disease 2019
Severe acute respiratory syndrome-related coronavirus 2
Pregnancy
Neurodevelopment
Maternal-fetal interface
Neuroimmune interactions
dc.subject.en.pt_BR.fl_str_mv Coronavirus disease 2019
Severe acute respiratory syndrome-related coronavirus 2
Pregnancy
Neurodevelopment
Maternal-fetal interface
Neuroimmune interactions
description Universidade Federal do Estado do Rio de Janeiro - UNIRIO. Programa de Biologia Celular e Molecular. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ, Brasil.
publishDate 2021
dc.date.accessioned.fl_str_mv 2021-05-25T18:49:03Z
dc.date.available.fl_str_mv 2021-05-25T18:49:03Z
dc.date.issued.fl_str_mv 2021
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv GRANJA, Marcelo Gomes et al. SARS-CoV-2 Infection in Pregnant Women: Neuroimmune-Endocrine Changes at the Maternal-Fetal Interface. Neuroimmunomodulation, v. 28, 32p, Apr. 2021
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/47365
dc.identifier.issn.pt_BR.fl_str_mv 1021-7401
dc.identifier.doi.none.fl_str_mv 10.1159/000515556
identifier_str_mv GRANJA, Marcelo Gomes et al. SARS-CoV-2 Infection in Pregnant Women: Neuroimmune-Endocrine Changes at the Maternal-Fetal Interface. Neuroimmunomodulation, v. 28, 32p, Apr. 2021
1021-7401
10.1159/000515556
url https://www.arca.fiocruz.br/handle/icict/47365
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Karger Publishers
publisher.none.fl_str_mv Karger Publishers
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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https://www.arca.fiocruz.br/bitstream/icict/47365/2/HugoCC_FariaNeto_etal_IOC_2021.pdf
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