Activity of Naturally Derived Antimicrobial Peptides against Filamentous Fungi Relevant for Agriculture

Detalhes bibliográficos
Autor(a) principal: Larrañaga, Patricia
Data de Publicação: 2012
Outros Autores: Diaz-Dellavalle, Paola, Cabrera, Andrea, Alem, Diego, Leoni, Carolina, Souza, Andre Luiz Almeida, De Simone, Salvatore Giovanni, Della-Rizza
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/15403
Resumo: Instituto Nacional de Investigación Agropecuaria (INIA Las Brujas). Estación Experimental Wilson Ferreira Aldunate. Laboratorio de Proteínas. Unidad de Biotecnología. Uruguay.
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spelling Larrañaga, PatriciaDiaz-Dellavalle, PaolaCabrera, AndreaAlem, DiegoLeoni, CarolinaSouza, Andre Luiz AlmeidaDe Simone, Salvatore GiovanniDella-Rizza2016-08-25T16:11:07Z2016-08-25T16:11:07Z2012LARRAÑAGA, Patria; et al. Activity of Naturally Derived Antimicrobial Peptides against Filamentous Fungi Relevant for Agriculture . Sustainable Agriculture Research; v. 1, n. 2; p.211-221, 2012.1927-050Xhttps://www.arca.fiocruz.br/handle/icict/1540310.5539/sar.v1n2p2111927-0518engCanadian Center of Science and EducationAtividade antifúngicaPeptídeos antimicrobianosAgriculturaAntimicrobial peptidesemporizinaPlc-2Pses3Antifungal activityActivity of Naturally Derived Antimicrobial Peptides against Filamentous Fungi Relevant for Agricultureinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleInstituto Nacional de Investigación Agropecuaria (INIA Las Brujas). Estación Experimental Wilson Ferreira Aldunate. Laboratorio de Proteínas. Unidad de Biotecnología. Uruguay.Instituto Nacional de Investigación Agropecuaria (INIA Las Brujas). Estación Experimental Wilson Ferreira Aldunate. Laboratorio de Proteínas. Unidad de Biotecnología. Uruguay.Instituto Nacional de Investigación Agropecuaria (INIA Las Brujas). Estación Experimental Wilson Ferreira Aldunate. Laboratorio de Proteínas. Unidad de Biotecnología. Uruguay.Instituto Nacional de Investigación Agropecuaria (INIA Las Brujas). Estación Experimental Wilson Ferreira Aldunate. Laboratorio de Proteínas. Unidad de Biotecnología. Uruguay.Instituto Nacional de Investigación Agropecuaria (INIA Las Brujas). Estación Experimental Wilson Ferreira Aldunate. Programa Nacional de Investigación de Producción y Sustentabilidad Ambiental. Departamento de Protección Vegetal. Uruguay.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Bioquímica de Proteínas e Peptídeos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Centro de Desenvolvimento Tecnológico em Saúde (CDTS). Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Nacional de Ciência e Tecnologia de Inovação em Doenças Negligenciadas. Rio de Janeiro, RJ, Brasil.Instituto Nacional de Investigación Agropecuaria (INIA Las Brujas). Estación Experimental Wilson Ferreira Aldunate. Laboratorio de Proteínas. Unidad de Biotecnología. Uruguay.The search for environmentally biocompatible and cost-effective methods to control filamentous fungi in agriculture is becoming increasingly urgent. In vitro antimicrobial activity of three synthetic peptides was investigated against some filamentous fungi with agricultural relevance. The peptides were an analog of Temporin called Temporizina, a fragment from Pleurocidin termed Plc-2, and a peptide identified from sesame seeds named Pses3. Antimicrobial activity of these peptides towards filamentous fungi has not been previously reported. Seven plant pathogenic or mycotoxigenic fungal species, isolated from plant tissues were assayed: Alternaria solani, Colletotrichum gloesporioides, Fulvia fulvum, Fusarium oxisporum, Aspergillus niger, A. ochraceus and Penicillium digitatum. Values of Minimum Inhibitory Concentration (MIC) and Minimum Fungicidal Concentration (MFC) were determined and compared with the commercially available fungicide Captan as a positive control. The peptides showing greatest inhibition were Pses3 and Plc-2 and C. gloesporioides was the most sensitive of the evaluated fungi. The MIC values for Plc-2 and Pses3 peptides ranged from 0.64 µM to 10.25 µM. These values were much lower than those observed for Captan, suggesting the potential of these peptides as fungicides. In particular, Pses3 is a novel peptide derived from sesame seeds not reported in databases.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/15403/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALandre_souza_etal_IOC_2012.pdfandre_souza_etal_IOC_2012.pdfapplication/pdf984613https://www.arca.fiocruz.br/bitstream/icict/15403/2/andre_souza_etal_IOC_2012.pdf061892278a6ac0ab9954f0adb399bc43MD52TEXTandre_souza_etal_IOC_2012.pdf.txtandre_souza_etal_IOC_2012.pdf.txtExtracted texttext/plain40102https://www.arca.fiocruz.br/bitstream/icict/15403/3/andre_souza_etal_IOC_2012.pdf.txtc7d6ee756b04372ab746641a449ed3cfMD53icict/154032018-12-29 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dc.title.pt_BR.fl_str_mv Activity of Naturally Derived Antimicrobial Peptides against Filamentous Fungi Relevant for Agriculture
title Activity of Naturally Derived Antimicrobial Peptides against Filamentous Fungi Relevant for Agriculture
spellingShingle Activity of Naturally Derived Antimicrobial Peptides against Filamentous Fungi Relevant for Agriculture
Larrañaga, Patricia
Atividade antifúngica
Peptídeos antimicrobianos
Agricultura
Antimicrobial peptides
emporizina
Plc-2
Pses3
Antifungal activity
title_short Activity of Naturally Derived Antimicrobial Peptides against Filamentous Fungi Relevant for Agriculture
title_full Activity of Naturally Derived Antimicrobial Peptides against Filamentous Fungi Relevant for Agriculture
title_fullStr Activity of Naturally Derived Antimicrobial Peptides against Filamentous Fungi Relevant for Agriculture
title_full_unstemmed Activity of Naturally Derived Antimicrobial Peptides against Filamentous Fungi Relevant for Agriculture
title_sort Activity of Naturally Derived Antimicrobial Peptides against Filamentous Fungi Relevant for Agriculture
author Larrañaga, Patricia
author_facet Larrañaga, Patricia
Diaz-Dellavalle, Paola
Cabrera, Andrea
Alem, Diego
Leoni, Carolina
Souza, Andre Luiz Almeida
De Simone, Salvatore Giovanni
Della-Rizza
author_role author
author2 Diaz-Dellavalle, Paola
Cabrera, Andrea
Alem, Diego
Leoni, Carolina
Souza, Andre Luiz Almeida
De Simone, Salvatore Giovanni
Della-Rizza
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Larrañaga, Patricia
Diaz-Dellavalle, Paola
Cabrera, Andrea
Alem, Diego
Leoni, Carolina
Souza, Andre Luiz Almeida
De Simone, Salvatore Giovanni
Della-Rizza
dc.subject.other.pt_BR.fl_str_mv Atividade antifúngica
Peptídeos antimicrobianos
Agricultura
topic Atividade antifúngica
Peptídeos antimicrobianos
Agricultura
Antimicrobial peptides
emporizina
Plc-2
Pses3
Antifungal activity
dc.subject.en.pt_BR.fl_str_mv Antimicrobial peptides
emporizina
Plc-2
Pses3
Antifungal activity
description Instituto Nacional de Investigación Agropecuaria (INIA Las Brujas). Estación Experimental Wilson Ferreira Aldunate. Laboratorio de Proteínas. Unidad de Biotecnología. Uruguay.
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2016-08-25T16:11:07Z
dc.date.available.fl_str_mv 2016-08-25T16:11:07Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv LARRAÑAGA, Patria; et al. Activity of Naturally Derived Antimicrobial Peptides against Filamentous Fungi Relevant for Agriculture . Sustainable Agriculture Research; v. 1, n. 2; p.211-221, 2012.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/15403
dc.identifier.issn.pt_BR.fl_str_mv 1927-050X
dc.identifier.doi.none.fl_str_mv 10.5539/sar.v1n2p211
dc.identifier.eissn.none.fl_str_mv 1927-0518
identifier_str_mv LARRAÑAGA, Patria; et al. Activity of Naturally Derived Antimicrobial Peptides against Filamentous Fungi Relevant for Agriculture . Sustainable Agriculture Research; v. 1, n. 2; p.211-221, 2012.
1927-050X
10.5539/sar.v1n2p211
1927-0518
url https://www.arca.fiocruz.br/handle/icict/15403
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Canadian Center of Science and Education
publisher.none.fl_str_mv Canadian Center of Science and Education
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/15403/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/15403/2/andre_souza_etal_IOC_2012.pdf
https://www.arca.fiocruz.br/bitstream/icict/15403/3/andre_souza_etal_IOC_2012.pdf.txt
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
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