Blastocystis sp. in splenic cysts: causative agent or accidental association? A unique case report

Detalhes bibliográficos
Autor(a) principal: Santos, Helena Lúcia Carneiro
Data de Publicação: 2014
Outros Autores: Sodré, Fernando Campos, Macedo, Heloisa Werneck de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/9966
Resumo: This work was financed by PAPES-VI/FIOCRUZ. The funders had no participation in the study design, data collection and analysis, decision to publish, or preparation of the manuscript.
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spelling Santos, Helena Lúcia CarneiroSodré, Fernando CamposMacedo, Heloisa Werneck de2015-04-14T12:38:09Z2015-04-14T12:38:09Z2014SANTOS, Helena Lúcia Carneiro et al. Parasites & Vectors, v.7, n. 207, 2014https://www.arca.fiocruz.br/handle/icict/996610.1186/1756-3305-7-207This work was financed by PAPES-VI/FIOCRUZ. The funders had no participation in the study design, data collection and analysis, decision to publish, or preparation of the manuscript.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Avaliação e Promoção da Saúde Ambiental. Rio de Janeiro, RJ, Brasil.Universidade Federal Fluminense. Departamento de Patologia. Niterói, RJ, Brasil.Universidade Federal Fluminense. Departamento de Patologia. Niterói, RJ, Brasil.Background: Blastocystis sp. is one of the most prevalent parasites found in human stool and has been recently considered an opportunistic emerging pathogen in immunocompromised individuals. However, cases of invasive intestinal infections and skin rashes have been attributed to infection by Blastocystis sp in immunocompetent individuals, suggesting that it is an emerging parasite with pathogenic potential. Findings: We present a case of a 22 year old female patient who complained of pain in the left hypochondrium. Ultrasonography and abdominal computed tomography scans showed two splenic cysts. The cyst fluid analysis demonstrated numerous Blastocystis sp.; PCR and DNA sequencing analyses confirmed the presence of Blastocystis subtype 3. Conclusions: This is, to our knowledge, the first case report of the presence of Blastocystis subtype 3 in extra-intestinal organs and is strong evidence that Blastocystis sp. is potentially pathogenic and invasive. However, further studies are required to determine the pathogenicity of the parasite.engBioMed CentralBlastocystis sp. in splenic cysts: causative agent or accidental association? A unique case reportinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleBlastocystis sppImmunocompetent individualPathogenicitySplenic cystVirulenciaVirulênciainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1914https://www.arca.fiocruz.br/bitstream/icict/9966/1/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD51ORIGINALsattamini_anaetal_IOC_2014.pdfapplication/pdf9178458https://www.arca.fiocruz.br/bitstream/icict/9966/2/sattamini_anaetal_IOC_2014.pdf4ce1e679c31a9ef76f14b3610de46b7bMD52TEXTsattamini_anaetal_IOC_2014.pdf.txtsattamini_anaetal_IOC_2014.pdf.txtExtracted texttext/plain11https://www.arca.fiocruz.br/bitstream/icict/9966/3/sattamini_anaetal_IOC_2014.pdf.txtb308b7fe5c1c2bbdc0cb686d451b84aaMD53icict/99662022-06-24 13:10:51.143oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-06-24T16:10:51Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Blastocystis sp. in splenic cysts: causative agent or accidental association? A unique case report
title Blastocystis sp. in splenic cysts: causative agent or accidental association? A unique case report
spellingShingle Blastocystis sp. in splenic cysts: causative agent or accidental association? A unique case report
Santos, Helena Lúcia Carneiro
Blastocystis spp
Immunocompetent individual
Pathogenicity
Splenic cyst
Virulencia
Virulência
title_short Blastocystis sp. in splenic cysts: causative agent or accidental association? A unique case report
title_full Blastocystis sp. in splenic cysts: causative agent or accidental association? A unique case report
title_fullStr Blastocystis sp. in splenic cysts: causative agent or accidental association? A unique case report
title_full_unstemmed Blastocystis sp. in splenic cysts: causative agent or accidental association? A unique case report
title_sort Blastocystis sp. in splenic cysts: causative agent or accidental association? A unique case report
author Santos, Helena Lúcia Carneiro
author_facet Santos, Helena Lúcia Carneiro
Sodré, Fernando Campos
Macedo, Heloisa Werneck de
author_role author
author2 Sodré, Fernando Campos
Macedo, Heloisa Werneck de
author2_role author
author
dc.contributor.author.fl_str_mv Santos, Helena Lúcia Carneiro
Sodré, Fernando Campos
Macedo, Heloisa Werneck de
dc.subject.en.pt_BR.fl_str_mv Blastocystis spp
Immunocompetent individual
Pathogenicity
Splenic cyst
topic Blastocystis spp
Immunocompetent individual
Pathogenicity
Splenic cyst
Virulencia
Virulência
dc.subject.es.pt_BR.fl_str_mv Virulencia
dc.subject.decs.pt_BR.fl_str_mv Virulência
description This work was financed by PAPES-VI/FIOCRUZ. The funders had no participation in the study design, data collection and analysis, decision to publish, or preparation of the manuscript.
publishDate 2014
dc.date.issued.fl_str_mv 2014
dc.date.accessioned.fl_str_mv 2015-04-14T12:38:09Z
dc.date.available.fl_str_mv 2015-04-14T12:38:09Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SANTOS, Helena Lúcia Carneiro et al. Parasites & Vectors, v.7, n. 207, 2014
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/9966
dc.identifier.doi.pt_BR.fl_str_mv 10.1186/1756-3305-7-207
identifier_str_mv SANTOS, Helena Lúcia Carneiro et al. Parasites & Vectors, v.7, n. 207, 2014
10.1186/1756-3305-7-207
url https://www.arca.fiocruz.br/handle/icict/9966
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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