Dried blood spot testing for the antenatal screening of HTLV, HIV, syphilis, toxoplasmosis and hepatitis B and C: prevalence, accuracy and operational aspects

Detalhes bibliográficos
Autor(a) principal: Boa-Sorte, Ney Cristian Amaral
Data de Publicação: 2014
Outros Autores: Purificação, Antônio, Amorim, Tatiana, Assunção, Lorena, Reis, Alan, Castro Filho, Bernardo Galvão
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/8153
Resumo: Associação de Pais e Amigos dos Excepcionais de Salvador – APAE. Salvador, BA, Brasil / Escola Bahiana de Medicina e Saúde Pública. Salvador, BA, Brasil
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spelling Boa-Sorte, Ney Cristian AmaralPurificação, AntônioAmorim, TatianaAssunção, LorenaReis, AlanCastro Filho, Bernardo Galvão2014-08-08T16:17:19Z2014-08-08T16:17:19Z2014BOA-SORTE, N. C. A. et al. Dried blood spot testing for the antenatal screening of HTLV, HIV, syphilis, toxoplasmosis and hepatitis B and C: prevalence, accuracy and operational aspects. Brazilian Journal of Infectious Diseases, 2014.1413-8670https://www.arca.fiocruz.br/handle/icict/815310.1016/j.bjid.2014.05.009engElsevier Editora LtdaDried blood spot testing for the antenatal screening of HTLV, HIV, syphilis, toxoplasmosis and hepatitis B and C: prevalence, accuracy and operational aspectsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleAssociação de Pais e Amigos dos Excepcionais de Salvador – APAE. Salvador, BA, Brasil / Escola Bahiana de Medicina e Saúde Pública. Salvador, BA, BrasilAssociação de Pais e Amigos dos Excepcionais de Salvador – APAE. Salvador, BA, Brasil / Secretaria Estadual de Saúde do Estado da Bahia – SESAB. Salvador, BA, BrasilUniversidade do Estado da Bahia - UNEB. Salvador, BA, BrasilAssociação de Pais e Amigos dos Excepcionais de Salvador – APAE. Salvador, BA, BrasilSecretaria Estadual de Saúde do Estado da Bahia – SESAB. Salvador, BA, Brasil / Secretaria Municipal de Saúde. Lauro de Freitas, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Laboratório Avançado de Saúde Pública. Salvador, BA, Brasil / Universidade Federal da Bahia. Faculdade de Farmácia. Salvador, BA, BrasiltIntroduction: Screening for vertically transmitted infection is mandatory and must be con-ducted at the first prenatal consultation. The most vulnerable women’s groups are those atthe lowest socio-economic level. Dried blood spot testing on filter paper could represent asecure way to screen pregnant women in the prenatal period.Methods: A cross-sectional study was conducted between November 2009 and March 2010,in the Metropolitan Region of Salvador, Bahia, Brazil, to compare the accuracy of the driedblood spot in filter paper and venipuncture serological as screening methods for HIV, HTLV,VHB, VHC, Treponema pallidum, and Toxoplasma gondii during prenatal period. Results of thevenous blood sample collected in tubes were considered the gold standard.Results: Serum samples and dried blood spot were obtained from 692 pregnant women agedbetween 14 and 42 years, with a median age of 26. Thirteen women were seropositive forT. gondii (1.88%; 95% CI: 0.60–2.71%), five for T. pallidum (0.72%; 95% CI: 0.15–1.61%), two forHBV (0.29%; 95% CI: 0.050.95%) and one for HTLV-1 (0.14%; 95% CI: 0.01–0.71%). No one waspositive for HCV and HIV. The dried blood spot accuracy for syphilis and HTLV were 100%(95% CI: 99.25–100) and 100% (95% CI: 99.45–100%), respectively. The average time betweenblood collection and recording of the sample in the reference laboratory was 4.93 (3.82) daysand between dried blood spot processing and active search for pregnant women was 3.44(4.27) days.Prenatal careInfectious diseasesSeroprevalenceDried blood spot testingainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALBoa-Sorte N Dried blood....pdfBoa-Sorte N Dried blood....pdfapplication/pdf838084https://www.arca.fiocruz.br/bitstream/icict/8153/1/Boa-Sorte%20N%20Dried%20blood....pdf10fea4f809cf23a655e5301afac044ecMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://www.arca.fiocruz.br/bitstream/icict/8153/2/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD52TEXTBoa-Sorte N Dried blood....pdf.txtBoa-Sorte N Dried blood....pdf.txtExtracted texttext/plain40918https://www.arca.fiocruz.br/bitstream/icict/8153/3/Boa-Sorte%20N%20Dried%20blood....pdf.txt20be24f22ff9ecc7504f9da341db8520MD53icict/81532023-03-15 14:33:24.147oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:24Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Dried blood spot testing for the antenatal screening of HTLV, HIV, syphilis, toxoplasmosis and hepatitis B and C: prevalence, accuracy and operational aspects
title Dried blood spot testing for the antenatal screening of HTLV, HIV, syphilis, toxoplasmosis and hepatitis B and C: prevalence, accuracy and operational aspects
spellingShingle Dried blood spot testing for the antenatal screening of HTLV, HIV, syphilis, toxoplasmosis and hepatitis B and C: prevalence, accuracy and operational aspects
Boa-Sorte, Ney Cristian Amaral
Prenatal care
Infectious diseases
Seroprevalence
Dried blood spot testinga
title_short Dried blood spot testing for the antenatal screening of HTLV, HIV, syphilis, toxoplasmosis and hepatitis B and C: prevalence, accuracy and operational aspects
title_full Dried blood spot testing for the antenatal screening of HTLV, HIV, syphilis, toxoplasmosis and hepatitis B and C: prevalence, accuracy and operational aspects
title_fullStr Dried blood spot testing for the antenatal screening of HTLV, HIV, syphilis, toxoplasmosis and hepatitis B and C: prevalence, accuracy and operational aspects
title_full_unstemmed Dried blood spot testing for the antenatal screening of HTLV, HIV, syphilis, toxoplasmosis and hepatitis B and C: prevalence, accuracy and operational aspects
title_sort Dried blood spot testing for the antenatal screening of HTLV, HIV, syphilis, toxoplasmosis and hepatitis B and C: prevalence, accuracy and operational aspects
author Boa-Sorte, Ney Cristian Amaral
author_facet Boa-Sorte, Ney Cristian Amaral
Purificação, Antônio
Amorim, Tatiana
Assunção, Lorena
Reis, Alan
Castro Filho, Bernardo Galvão
author_role author
author2 Purificação, Antônio
Amorim, Tatiana
Assunção, Lorena
Reis, Alan
Castro Filho, Bernardo Galvão
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Boa-Sorte, Ney Cristian Amaral
Purificação, Antônio
Amorim, Tatiana
Assunção, Lorena
Reis, Alan
Castro Filho, Bernardo Galvão
dc.subject.en.pt_BR.fl_str_mv Prenatal care
Infectious diseases
Seroprevalence
Dried blood spot testinga
topic Prenatal care
Infectious diseases
Seroprevalence
Dried blood spot testinga
description Associação de Pais e Amigos dos Excepcionais de Salvador – APAE. Salvador, BA, Brasil / Escola Bahiana de Medicina e Saúde Pública. Salvador, BA, Brasil
publishDate 2014
dc.date.accessioned.fl_str_mv 2014-08-08T16:17:19Z
dc.date.available.fl_str_mv 2014-08-08T16:17:19Z
dc.date.issued.fl_str_mv 2014
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv BOA-SORTE, N. C. A. et al. Dried blood spot testing for the antenatal screening of HTLV, HIV, syphilis, toxoplasmosis and hepatitis B and C: prevalence, accuracy and operational aspects. Brazilian Journal of Infectious Diseases, 2014.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/8153
dc.identifier.issn.none.fl_str_mv 1413-8670
dc.identifier.doi.none.fl_str_mv 10.1016/j.bjid.2014.05.009
identifier_str_mv BOA-SORTE, N. C. A. et al. Dried blood spot testing for the antenatal screening of HTLV, HIV, syphilis, toxoplasmosis and hepatitis B and C: prevalence, accuracy and operational aspects. Brazilian Journal of Infectious Diseases, 2014.
1413-8670
10.1016/j.bjid.2014.05.009
url https://www.arca.fiocruz.br/handle/icict/8153
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier Editora Ltda
publisher.none.fl_str_mv Elsevier Editora Ltda
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
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reponame_str Repositório Institucional da FIOCRUZ (ARCA)
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