Inclusion Complexes of Non-Steroidal Anti-Inflammatory Drugs with Cyclodextrins: A Systematic Review
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2021 |
| Outros Autores: | , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| DOI: | 10.3390/biom11030361 |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/46535 |
Resumo: | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Laboratório de Investigação em Genética e Hematologia Translacional, Salvador, BA, Brasil. |
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Miranda, Gustavo MarinhoSantos, Vitória Ohana Ramos eBessa, Jonatas ReisTeles, Yanna C. F.Yahouédéhou, Setondji Cocou Modeste AlexandreGoncalves, Marilda de SouzaRibeiro Filho, Jaime2021-04-07T12:26:24Z2021-04-07T12:26:24Z2021MIRANDA, Gustavo Marinho et al. Inclusion Complexes of Non-Steroidal Anti-Inflammatory Drugs with Cyclodextrins: A Systematic Review. Biomolecules, v. 11, 2021.2218-273Xhttps://www.arca.fiocruz.br/handle/icict/4653510.3390/biom11030361engMDPICiclodextrinasAnti-Inflamatórios não EsteroidesRevisão sistemáticaPreparações FarmacêuticasCyclodextrinsNon-steroidal anti-inflammatory drugsInclusion complexesInclusion Complexes of Non-Steroidal Anti-Inflammatory Drugs with Cyclodextrins: A Systematic Reviewinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Gonçalo Moniz. Laboratório de Investigação em Genética e Hematologia Translacional, Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Laboratório de Investigação em Genética e Hematologia Translacional, Salvador, BA, Brasil.Federal University of Bahia. Institute of Psychology. Salvador, BA, Brazil.Federal University of Paraiba. Agrarian Sciences Center. Department of Chemistry and Physics. Areia, PB, Brazil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Laboratório de Investigação em Genética e Hematologia Translacional, Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Laboratório de Investigação em Genética e Hematologia Translacional, Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Laboratório de Investigação em Genética e Hematologia Translacional, Salvador, BA, Brasil.Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most widely used classes of medicines in the treatment of inflammation, fever, and pain. However, evidence has demonstrated that these drugs can induce significant toxicity. In the search for innovative strategies to overcome NSAID-related problems, the incorporation of drugs into cyclodextrins (CDs) has demonstrated promising results. This study aims to review the impact of cyclodextrin incorporation on the biopharmaceutical and pharmacological properties of non-steroidal anti-inflammatory drugs. A systematic search for papers published between 2010 and 2020 was carried out using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol and the following search terms: “Complexation”; AND “Cyclodextrin”; AND “non-steroidal anti-inflammatory drug”. A total of 24 different NSAIDs, 12 types of CDs, and 60 distinct inclusion complexes were identified, with meloxicam and -CD appearing in most studies. The results of the present review suggest that CDs are drug delivery systems capable of improving the pharmacological and biopharmaceutical properties of non-steroidal anti-inflammatory drugs.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83097https://www.arca.fiocruz.br/bitstream/icict/46535/1/license.txt36b51ef91c52b5338d9d29ba0cc807bcMD51ORIGINALMiranda, Gustavo Marinho Inclusion....pdfMiranda, Gustavo Marinho Inclusion....pdfapplication/pdf1550691https://www.arca.fiocruz.br/bitstream/icict/46535/2/Miranda%2c%20Gustavo%20Marinho%20Inclusion....pdf765113f6f56243f3ffade39e13d29836MD52TEXTMiranda, Gustavo Marinho Inclusion....pdf.txtMiranda, Gustavo Marinho Inclusion....pdf.txtExtracted 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| dc.title.pt_BR.fl_str_mv |
Inclusion Complexes of Non-Steroidal Anti-Inflammatory Drugs with Cyclodextrins: A Systematic Review |
| title |
Inclusion Complexes of Non-Steroidal Anti-Inflammatory Drugs with Cyclodextrins: A Systematic Review |
| spellingShingle |
Inclusion Complexes of Non-Steroidal Anti-Inflammatory Drugs with Cyclodextrins: A Systematic Review Miranda, Gustavo Marinho Ciclodextrinas Anti-Inflamatórios não Esteroides Revisão sistemática Preparações Farmacêuticas Cyclodextrins Non-steroidal anti-inflammatory drugs Inclusion complexes |
| title_short |
Inclusion Complexes of Non-Steroidal Anti-Inflammatory Drugs with Cyclodextrins: A Systematic Review |
| title_full |
Inclusion Complexes of Non-Steroidal Anti-Inflammatory Drugs with Cyclodextrins: A Systematic Review |
| title_fullStr |
Inclusion Complexes of Non-Steroidal Anti-Inflammatory Drugs with Cyclodextrins: A Systematic Review |
| title_full_unstemmed |
Inclusion Complexes of Non-Steroidal Anti-Inflammatory Drugs with Cyclodextrins: A Systematic Review |
| title_sort |
Inclusion Complexes of Non-Steroidal Anti-Inflammatory Drugs with Cyclodextrins: A Systematic Review |
| author |
Miranda, Gustavo Marinho |
| author_facet |
Miranda, Gustavo Marinho Santos, Vitória Ohana Ramos e Bessa, Jonatas Reis Teles, Yanna C. F. Yahouédéhou, Setondji Cocou Modeste Alexandre Goncalves, Marilda de Souza Ribeiro Filho, Jaime |
| author_role |
author |
| author2 |
Santos, Vitória Ohana Ramos e Bessa, Jonatas Reis Teles, Yanna C. F. Yahouédéhou, Setondji Cocou Modeste Alexandre Goncalves, Marilda de Souza Ribeiro Filho, Jaime |
| author2_role |
author author author author author author |
| dc.contributor.author.fl_str_mv |
Miranda, Gustavo Marinho Santos, Vitória Ohana Ramos e Bessa, Jonatas Reis Teles, Yanna C. F. Yahouédéhou, Setondji Cocou Modeste Alexandre Goncalves, Marilda de Souza Ribeiro Filho, Jaime |
| dc.subject.other.pt_BR.fl_str_mv |
Ciclodextrinas Anti-Inflamatórios não Esteroides Revisão sistemática Preparações Farmacêuticas |
| topic |
Ciclodextrinas Anti-Inflamatórios não Esteroides Revisão sistemática Preparações Farmacêuticas Cyclodextrins Non-steroidal anti-inflammatory drugs Inclusion complexes |
| dc.subject.en.pt_BR.fl_str_mv |
Cyclodextrins Non-steroidal anti-inflammatory drugs Inclusion complexes |
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Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Laboratório de Investigação em Genética e Hematologia Translacional, Salvador, BA, Brasil. |
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2021 |
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2021-04-07T12:26:24Z |
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2021-04-07T12:26:24Z |
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2021 |
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MIRANDA, Gustavo Marinho et al. Inclusion Complexes of Non-Steroidal Anti-Inflammatory Drugs with Cyclodextrins: A Systematic Review. Biomolecules, v. 11, 2021. |
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https://www.arca.fiocruz.br/handle/icict/46535 |
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2218-273X |
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10.3390/biom11030361 |
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MIRANDA, Gustavo Marinho et al. Inclusion Complexes of Non-Steroidal Anti-Inflammatory Drugs with Cyclodextrins: A Systematic Review. Biomolecules, v. 11, 2021. 2218-273X 10.3390/biom11030361 |
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