Different patterns of disease in two inbred mouse strains infected with a clone of Leishmania mexicana amazonensis

Detalhes bibliográficos
Autor(a) principal: Barral Netto, Manoel
Data de Publicação: 1987
Outros Autores: Cardoso, Silvia Andrade, Barral, Aldina Maria Prado
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/26346
Resumo: Grant AI-16282 (National Institutes of Health - USA) and from the Conselho Nacional de Desenvolvimento Cientifico e Tecnològico (CNPq-Brasil).
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spelling Barral Netto, ManoelCardoso, Silvia AndradeBarral, Aldina Maria Prado2018-05-09T18:11:44Z2018-05-09T18:11:44Z1987BARRAL NETTO, M.; CARDOSO, A. A.; BARRAL, A. M. P. Different patterns of disease in two inbred mouse strains infected with a clone of Leishmania mexicana amazonensis. Acta Tropica, v. 44, p. 5-11, 1987.0001-706Xhttps://www.arca.fiocruz.br/handle/icict/26346Grant AI-16282 (National Institutes of Health - USA) and from the Conselho Nacional de Desenvolvimento Cientifico e Tecnològico (CNPq-Brasil).Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Salvador, BA, BrasilUniversidade Federal da Bahia. Hospital Prof. Edgard Santos. Laboratorio de Imunologia. Salvador, BA, BrasilWe have infected BALB/c and C57BL/6 mice with a cloned Leishmania mexicana amazonensis population, obtained from the "Maria" strain. Progres¬ sion of infection and histopathological examination confirmed the extreme susceptibility of BALB/c mice and the resistant pattern ofthe C57 BL/6. Anti- Leishmania antibody titers were higher in BALB/c than in C57BL/6 mice through the period of infection. Tests of delayed type hypersensitivity reaction with Leishmania antigens were positive in both strains in the beginning ofthe infection, but were negative later on in BALB/c mice. Our results are similar to those obtained with mixed parasite populations, and rule out the possibility of selection among different parasite subpopulations as responsible for the diver¬ gent course of the disease exhibited by these two strains of mice.engElsevierLeishmaniose cutâneaLeishmaniose murinaLeishmaniaParasite clonesL. mexicanaCutaneous leishmaniasisMurine leishmaniasisLeishmaniaClones de parasitasL. mexicanaDifferent patterns of disease in two inbred mouse strains infected with a clone of Leishmania mexicana amazonensisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/26346/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALBarral MN Different patterns of disease in two inbred....pdfBarral MN Different patterns 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dc.title.pt_BR.fl_str_mv Different patterns of disease in two inbred mouse strains infected with a clone of Leishmania mexicana amazonensis
title Different patterns of disease in two inbred mouse strains infected with a clone of Leishmania mexicana amazonensis
spellingShingle Different patterns of disease in two inbred mouse strains infected with a clone of Leishmania mexicana amazonensis
Barral Netto, Manoel
Leishmaniose cutânea
Leishmaniose murina
Leishmania
Parasite clones
L. mexicana
Cutaneous leishmaniasis
Murine leishmaniasis
Leishmania
Clones de parasitas
L. mexicana
title_short Different patterns of disease in two inbred mouse strains infected with a clone of Leishmania mexicana amazonensis
title_full Different patterns of disease in two inbred mouse strains infected with a clone of Leishmania mexicana amazonensis
title_fullStr Different patterns of disease in two inbred mouse strains infected with a clone of Leishmania mexicana amazonensis
title_full_unstemmed Different patterns of disease in two inbred mouse strains infected with a clone of Leishmania mexicana amazonensis
title_sort Different patterns of disease in two inbred mouse strains infected with a clone of Leishmania mexicana amazonensis
author Barral Netto, Manoel
author_facet Barral Netto, Manoel
Cardoso, Silvia Andrade
Barral, Aldina Maria Prado
author_role author
author2 Cardoso, Silvia Andrade
Barral, Aldina Maria Prado
author2_role author
author
dc.contributor.author.fl_str_mv Barral Netto, Manoel
Cardoso, Silvia Andrade
Barral, Aldina Maria Prado
dc.subject.other.pt_BR.fl_str_mv Leishmaniose cutânea
Leishmaniose murina
Leishmania
Parasite clones
L. mexicana
topic Leishmaniose cutânea
Leishmaniose murina
Leishmania
Parasite clones
L. mexicana
Cutaneous leishmaniasis
Murine leishmaniasis
Leishmania
Clones de parasitas
L. mexicana
dc.subject.en.pt_BR.fl_str_mv Cutaneous leishmaniasis
Murine leishmaniasis
Leishmania
Clones de parasitas
L. mexicana
description Grant AI-16282 (National Institutes of Health - USA) and from the Conselho Nacional de Desenvolvimento Cientifico e Tecnològico (CNPq-Brasil).
publishDate 1987
dc.date.issued.fl_str_mv 1987
dc.date.accessioned.fl_str_mv 2018-05-09T18:11:44Z
dc.date.available.fl_str_mv 2018-05-09T18:11:44Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.citation.fl_str_mv BARRAL NETTO, M.; CARDOSO, A. A.; BARRAL, A. M. P. Different patterns of disease in two inbred mouse strains infected with a clone of Leishmania mexicana amazonensis. Acta Tropica, v. 44, p. 5-11, 1987.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/26346
dc.identifier.issn.pt_BR.fl_str_mv 0001-706X
identifier_str_mv BARRAL NETTO, M.; CARDOSO, A. A.; BARRAL, A. M. P. Different patterns of disease in two inbred mouse strains infected with a clone of Leishmania mexicana amazonensis. Acta Tropica, v. 44, p. 5-11, 1987.
0001-706X
url https://www.arca.fiocruz.br/handle/icict/26346
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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