BCG Moreau Rio de Janeiro - An oral vaccine against tuberculosis – Review

Detalhes bibliográficos
Autor(a) principal: Andrade, Thereza Christina Benévolo de
Data de Publicação: 2005
Outros Autores: Maia, Renata Monteiro, Cosgrove, Catherine, Castello Branco, Luiz Roberto R.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/44556
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Laboratório de Imunologia Clínica. Rio de Janeiro, RJ, Brasil.
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spelling Andrade, Thereza Christina Benévolo deMaia, Renata MonteiroCosgrove, CatherineCastello Branco, Luiz Roberto R.2020-11-20T14:37:21Z2020-11-20T14:37:21Z2005ANDRADE, Thereza Christina Benévolo de et al. BCG Moreau Rio de Janeiro - An oral vaccine against tuberculosis — review. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 100, n. 5, p. 459-465, Aug. 2005.0074-0276https://www.arca.fiocruz.br/handle/icict/4455610.1590/S0074-027620050005000021678-8060engFundação Oswaldo Cruz. Instituto Oswaldo Cruz.BCG Moreau Rio de JaneiroVacina oralRevisãoBCG Moreau Rio de JaneiroOral vaccineReviewBCG Moreau Rio de Janeiro - An oral vaccine against tuberculosis – Reviewinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Laboratório de Imunologia Clínica. Rio de Janeiro, RJ, Brasil.Fundação Ataulpho de Paiva. Centro de Pesquisas Arlindo de Assis. Rio de Janeiro, RJ, Brasil.St. George's Hospital Medical School. Division of Infectious Diseases. London, UK.Fundação Ataulpho de Paiva. Centro de Pesquisas Arlindo de Assis. Rio de Janeiro, RJ, Brasil.The vaccine Bacillus of Calmette Guérin (BCG) was originally developed in France as an oral vaccine against tuberculosis. The oral use of this vaccine was replaced by the parenteral route in almost all countries after the Lubeck disaster. In contrast, Brazil retained the oral delivery of the vaccine until the mid-seventies when it was replaced by the intradermal route. This change in route of delivery was mainly secondary to pressure by medical practitioners based on the poor responses of oral immunized subjects to purified protein derivative (PPD) skin tests. Even after the change of route of delivery, Ataulpho de Paiva Foundation continued making the oral vaccine. Currently, BCG Moreau has been described as one of the most immunogenic and with fewer side effects than other BCGs. The genomics, proteomics and vaccine trials for oral BCG Moreau Rio de Janeiro are currently under investigation. In this review, we intend to describe the history of BCG Moreau Rio de Janeiro in Brazil.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/44556/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALTherezaC_Andrade_etal_IOC_2005.pdfTherezaC_Andrade_etal_IOC_2005.pdfapplication/pdf6101214https://www.arca.fiocruz.br/bitstream/icict/44556/2/TherezaC_Andrade_etal_IOC_2005.pdf09bde0b37399ebdbaf1c9692c6eb94ceMD52TEXTTherezaC_Andrade_etal_IOC_2005.pdf.txtTherezaC_Andrade_etal_IOC_2005.pdf.txtExtracted texttext/plain29914https://www.arca.fiocruz.br/bitstream/icict/44556/3/TherezaC_Andrade_etal_IOC_2005.pdf.txtd08e9fa549de4145bf6e291c6ac9f3feMD53icict/445562020-11-21 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dc.title.pt_BR.fl_str_mv BCG Moreau Rio de Janeiro - An oral vaccine against tuberculosis – Review
title BCG Moreau Rio de Janeiro - An oral vaccine against tuberculosis – Review
spellingShingle BCG Moreau Rio de Janeiro - An oral vaccine against tuberculosis – Review
Andrade, Thereza Christina Benévolo de
BCG Moreau Rio de Janeiro
Vacina oral
Revisão
BCG Moreau Rio de Janeiro
Oral vaccine
Review
title_short BCG Moreau Rio de Janeiro - An oral vaccine against tuberculosis – Review
title_full BCG Moreau Rio de Janeiro - An oral vaccine against tuberculosis – Review
title_fullStr BCG Moreau Rio de Janeiro - An oral vaccine against tuberculosis – Review
title_full_unstemmed BCG Moreau Rio de Janeiro - An oral vaccine against tuberculosis – Review
title_sort BCG Moreau Rio de Janeiro - An oral vaccine against tuberculosis – Review
author Andrade, Thereza Christina Benévolo de
author_facet Andrade, Thereza Christina Benévolo de
Maia, Renata Monteiro
Cosgrove, Catherine
Castello Branco, Luiz Roberto R.
author_role author
author2 Maia, Renata Monteiro
Cosgrove, Catherine
Castello Branco, Luiz Roberto R.
author2_role author
author
author
dc.contributor.author.fl_str_mv Andrade, Thereza Christina Benévolo de
Maia, Renata Monteiro
Cosgrove, Catherine
Castello Branco, Luiz Roberto R.
dc.subject.other.pt_BR.fl_str_mv BCG Moreau Rio de Janeiro
Vacina oral
Revisão
topic BCG Moreau Rio de Janeiro
Vacina oral
Revisão
BCG Moreau Rio de Janeiro
Oral vaccine
Review
dc.subject.en.pt_BR.fl_str_mv BCG Moreau Rio de Janeiro
Oral vaccine
Review
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Laboratório de Imunologia Clínica. Rio de Janeiro, RJ, Brasil.
publishDate 2005
dc.date.issued.fl_str_mv 2005
dc.date.accessioned.fl_str_mv 2020-11-20T14:37:21Z
dc.date.available.fl_str_mv 2020-11-20T14:37:21Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv ANDRADE, Thereza Christina Benévolo de et al. BCG Moreau Rio de Janeiro - An oral vaccine against tuberculosis — review. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 100, n. 5, p. 459-465, Aug. 2005.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/44556
dc.identifier.issn.pt_BR.fl_str_mv 0074-0276
dc.identifier.doi.none.fl_str_mv 10.1590/S0074-02762005000500002
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv ANDRADE, Thereza Christina Benévolo de et al. BCG Moreau Rio de Janeiro - An oral vaccine against tuberculosis — review. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 100, n. 5, p. 459-465, Aug. 2005.
0074-0276
10.1590/S0074-02762005000500002
1678-8060
url https://www.arca.fiocruz.br/handle/icict/44556
dc.language.iso.fl_str_mv eng
language eng
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dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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