Trypanosoma cruzi: experimental Chagas`Disease in Rhesus monkeys, II. Ultrastructural and cytochemical studies of Peroxidase and Acid Phosphatase activities

Detalhes bibliográficos
Autor(a) principal: Meirelles, Maria de Nazareth Leal de
Data de Publicação: 1990
Outros Autores: Almeida, Maria da Glória Bonecini, Pessoa, Maria Heleosina Ribeiro, Castro, Bernardo Galvão
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/43378
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Ultraestrutura e Biologia Celular. Rio de Janeiro, RJ, Brasil.
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spelling Meirelles, Maria de Nazareth Leal deAlmeida, Maria da Glória BoneciniPessoa, Maria Heleosina RibeiroCastro, Bernardo Galvão2020-09-15T15:00:38Z2020-09-15T15:00:38Z1990MEIRELLES, Maria de Nazareth Leal de et al. Trypanosoma cruzi: experimental Chagas' disease in Rhesus monkeys. II. Ultraestructural and cytochemical studies of peroxidase and acid phosphatase activities. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 85, n. 2, p. 173-181, Apr./Aug. 1990.0074-0206https://www.arca.fiocruz.br/handle/icict/4337810.1590/S0074-027619900002000051678-8060engFundação Oswaldo Cruz. Instituto Oswaldo CruzDoença de ChagasPeroxidase atividadeCitoquímica ultraestruturalFosfatase ácidaMacacos rhesusUltrastructural cytochemistryPeroxidase activityChagas DiseaseAcid phosphataseRhesus monkeysTrypanosoma cruzi: experimental Chagas`Disease in Rhesus monkeys, II. Ultrastructural and cytochemical studies of Peroxidase and Acid Phosphatase activitiesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Ultraestrutura e Biologia Celular. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. WHO Colaborating Center for Research and Training in Parasitic Disease. Rio de Janeiro, RJ, Brasil.Universidade do Estado do Rio de Janeiro. Serviço de Microbiologia e Imunologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. WHO Colaborating Center for Research and Training in Parasitic Disease. Rio de Janeiro, RJ, Brasil.Ultrastructural and cytochemical studies of peroxidase and acid phosphatase were performed in skin, lymph node and heart muscle tissue of thesus monkeys with experimental Chagas's disease. At the site of inoculation ther was a proliferative reaction with the presence of immature macrophages revealed by peroxidase technique. At the lymph node a difuse inflammatory exudate with mononuclear cells, fibroblasts and immature activated macrophages reproduces the human patrtern of acute Chagas' disease inflamatory lesions. The hearth muscle cells present different degrees of degenerative alterations and a striking increase in the number of lysosomal profiles that exhibit acid hydrolase reaction product. A strong inflammatory reaction was present due to lymphocytic infiltrate or due to eosinophil granulocytes associated to ruptured cells. The present study provides some experimental evidences that the monkey model could be used as a reliable model to characterize histopathological alterations of the human disease.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/43378/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALBernadoGCastro_MNLMeirelles_etal_IOC_1990.pdfBernadoGCastro_MNLMeirelles_etal_IOC_1990.pdfapplication/pdf3622590https://www.arca.fiocruz.br/bitstream/icict/43378/2/BernadoGCastro_MNLMeirelles_etal_IOC_1990.pdf033a52fd4f82874d5663603f85fd6392MD52TEXTBernadoGCastro_MNLMeirelles_etal_IOC_1990.pdf.txtBernadoGCastro_MNLMeirelles_etal_IOC_1990.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Trypanosoma cruzi: experimental Chagas`Disease in Rhesus monkeys, II. Ultrastructural and cytochemical studies of Peroxidase and Acid Phosphatase activities
title Trypanosoma cruzi: experimental Chagas`Disease in Rhesus monkeys, II. Ultrastructural and cytochemical studies of Peroxidase and Acid Phosphatase activities
spellingShingle Trypanosoma cruzi: experimental Chagas`Disease in Rhesus monkeys, II. Ultrastructural and cytochemical studies of Peroxidase and Acid Phosphatase activities
Meirelles, Maria de Nazareth Leal de
Doença de Chagas
Peroxidase atividade
Citoquímica ultraestrutural
Fosfatase ácida
Macacos rhesus
Ultrastructural cytochemistry
Peroxidase activity
Chagas Disease
Acid phosphatase
Rhesus monkeys
title_short Trypanosoma cruzi: experimental Chagas`Disease in Rhesus monkeys, II. Ultrastructural and cytochemical studies of Peroxidase and Acid Phosphatase activities
title_full Trypanosoma cruzi: experimental Chagas`Disease in Rhesus monkeys, II. Ultrastructural and cytochemical studies of Peroxidase and Acid Phosphatase activities
title_fullStr Trypanosoma cruzi: experimental Chagas`Disease in Rhesus monkeys, II. Ultrastructural and cytochemical studies of Peroxidase and Acid Phosphatase activities
title_full_unstemmed Trypanosoma cruzi: experimental Chagas`Disease in Rhesus monkeys, II. Ultrastructural and cytochemical studies of Peroxidase and Acid Phosphatase activities
title_sort Trypanosoma cruzi: experimental Chagas`Disease in Rhesus monkeys, II. Ultrastructural and cytochemical studies of Peroxidase and Acid Phosphatase activities
author Meirelles, Maria de Nazareth Leal de
author_facet Meirelles, Maria de Nazareth Leal de
Almeida, Maria da Glória Bonecini
Pessoa, Maria Heleosina Ribeiro
Castro, Bernardo Galvão
author_role author
author2 Almeida, Maria da Glória Bonecini
Pessoa, Maria Heleosina Ribeiro
Castro, Bernardo Galvão
author2_role author
author
author
dc.contributor.author.fl_str_mv Meirelles, Maria de Nazareth Leal de
Almeida, Maria da Glória Bonecini
Pessoa, Maria Heleosina Ribeiro
Castro, Bernardo Galvão
dc.subject.other.pt_BR.fl_str_mv Doença de Chagas
Peroxidase atividade
Citoquímica ultraestrutural
Fosfatase ácida
Macacos rhesus
topic Doença de Chagas
Peroxidase atividade
Citoquímica ultraestrutural
Fosfatase ácida
Macacos rhesus
Ultrastructural cytochemistry
Peroxidase activity
Chagas Disease
Acid phosphatase
Rhesus monkeys
dc.subject.en.pt_BR.fl_str_mv Ultrastructural cytochemistry
Peroxidase activity
Chagas Disease
Acid phosphatase
Rhesus monkeys
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Ultraestrutura e Biologia Celular. Rio de Janeiro, RJ, Brasil.
publishDate 1990
dc.date.issued.fl_str_mv 1990
dc.date.accessioned.fl_str_mv 2020-09-15T15:00:38Z
dc.date.available.fl_str_mv 2020-09-15T15:00:38Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv MEIRELLES, Maria de Nazareth Leal de et al. Trypanosoma cruzi: experimental Chagas' disease in Rhesus monkeys. II. Ultraestructural and cytochemical studies of peroxidase and acid phosphatase activities. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 85, n. 2, p. 173-181, Apr./Aug. 1990.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/43378
dc.identifier.issn.pt_BR.fl_str_mv 0074-0206
dc.identifier.doi.none.fl_str_mv 10.1590/S0074-02761990000200005
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv MEIRELLES, Maria de Nazareth Leal de et al. Trypanosoma cruzi: experimental Chagas' disease in Rhesus monkeys. II. Ultraestructural and cytochemical studies of peroxidase and acid phosphatase activities. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 85, n. 2, p. 173-181, Apr./Aug. 1990.
0074-0206
10.1590/S0074-02761990000200005
1678-8060
url https://www.arca.fiocruz.br/handle/icict/43378
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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