Disease cutaneous leishmaniosis caused by Leishmania martiniquensis in a horse in Florida

Detalhes bibliográficos
Autor(a) principal: Menezes, R. C.
Data de Publicação: 2019
Outros Autores: Campos, M. P., Popielarczyk, M., Kiupel, M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/37668
Resumo: 2020-12-06
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spelling Menezes, R. C.Campos, M. P.Popielarczyk, M.Kiupel, M.2019-12-06T13:20:53Z2019-12-06T13:20:53Z2019MENEZES, R. C. et al. Cutaneous leishmaniosis caused by Leishmania martiniquensis in a horse in Florida. Journal of Comparative Pathology, v. 173, p. 13-18, 2019.0021-9975https://www.arca.fiocruz.br/handle/icict/3766810.1016/j.jcpa.2019.09.011engElsevierDisease cutaneous leishmaniosis caused by Leishmania martiniquensis in a horse in Floridainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2020-12-06Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil.Antech Diagnostics. Lake Success, NY, USA.Michigan State University. Veterinary Diagnostic Laboratory. East Lansing, MI, USA.We report a new case of cutaneous leishmaniosis caused by Leishmania (Mundinia) martiniquensis in a horse in Florida, USA. A 10-year-old neutered male Quarter horse was presented with multifocal to coalescing, raised, ulcerated and oozing, non-healing wounds on both pinnae of several weeks’ duration. After a few months, the lesions regressed spontaneously. Biopsies of the lesions were performed with microscopical findings of epidermal hyperplasia with multifocal ulceration and focally extensive, dermal pyogranulomatous inflammation with numerous intact and degenerate neutrophils being surrounded by epithelioid macrophages, lymphocytes and plasma cells, as well as rare eosinophils. Within the macrophages, and freely within the inflammatory infiltrate, were small (2e4 mm) round, basophilic protozoal organisms. Immunohistochemistry and colourimetric in-situ hybridization were positive for amastigote forms of Leishmania spp. The species L. martiniquensis was identified by polymerase chain reaction targeting the ITS-1 gene performed with extracts from formalin-fixed and paraffin wax-embedded samples of skin lesions. L. martiniquensis causes an ulcerative pyogranulomatous dermatitis in horses with spontaneous healing. This second autochthonous case in Florida, 5 years after the first case, suggests that this parasite may have become endemic in this state.HorseLeishmaniosisPathologySkin lesionsinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83104https://www.arca.fiocruz.br/bitstream/icict/37668/1/license.txt79178e5f2a0eb066867a274556814938MD51ORIGINALve_Menezes_R_etal_INI_2019.pdfve_Menezes_R_etal_INI_2019.pdfapplication/pdf1984899https://www.arca.fiocruz.br/bitstream/icict/37668/2/ve_Menezes_R_etal_INI_2019.pdfdb2521a9b52c19b1f8604331c010edd6MD52TEXTve_Menezes_R_etal_INI_2019.pdf.txtve_Menezes_R_etal_INI_2019.pdf.txtExtracted texttext/plain25260https://www.arca.fiocruz.br/bitstream/icict/37668/3/ve_Menezes_R_etal_INI_2019.pdf.txt8d21dad5ec0494989c902b3794363c56MD53icict/376682021-03-24 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dc.title.pt_BR.fl_str_mv Disease cutaneous leishmaniosis caused by Leishmania martiniquensis in a horse in Florida
title Disease cutaneous leishmaniosis caused by Leishmania martiniquensis in a horse in Florida
spellingShingle Disease cutaneous leishmaniosis caused by Leishmania martiniquensis in a horse in Florida
Menezes, R. C.
Horse
Leishmaniosis
Pathology
Skin lesions
title_short Disease cutaneous leishmaniosis caused by Leishmania martiniquensis in a horse in Florida
title_full Disease cutaneous leishmaniosis caused by Leishmania martiniquensis in a horse in Florida
title_fullStr Disease cutaneous leishmaniosis caused by Leishmania martiniquensis in a horse in Florida
title_full_unstemmed Disease cutaneous leishmaniosis caused by Leishmania martiniquensis in a horse in Florida
title_sort Disease cutaneous leishmaniosis caused by Leishmania martiniquensis in a horse in Florida
author Menezes, R. C.
author_facet Menezes, R. C.
Campos, M. P.
Popielarczyk, M.
Kiupel, M.
author_role author
author2 Campos, M. P.
Popielarczyk, M.
Kiupel, M.
author2_role author
author
author
dc.contributor.author.fl_str_mv Menezes, R. C.
Campos, M. P.
Popielarczyk, M.
Kiupel, M.
dc.subject.en.pt_BR.fl_str_mv Horse
Leishmaniosis
Pathology
Skin lesions
topic Horse
Leishmaniosis
Pathology
Skin lesions
description 2020-12-06
publishDate 2019
dc.date.accessioned.fl_str_mv 2019-12-06T13:20:53Z
dc.date.available.fl_str_mv 2019-12-06T13:20:53Z
dc.date.issued.fl_str_mv 2019
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv MENEZES, R. C. et al. Cutaneous leishmaniosis caused by Leishmania martiniquensis in a horse in Florida. Journal of Comparative Pathology, v. 173, p. 13-18, 2019.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/37668
dc.identifier.issn.pt_BR.fl_str_mv 0021-9975
dc.identifier.doi.none.fl_str_mv 10.1016/j.jcpa.2019.09.011
identifier_str_mv MENEZES, R. C. et al. Cutaneous leishmaniosis caused by Leishmania martiniquensis in a horse in Florida. Journal of Comparative Pathology, v. 173, p. 13-18, 2019.
0021-9975
10.1016/j.jcpa.2019.09.011
url https://www.arca.fiocruz.br/handle/icict/37668
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
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instacron_str FIOCRUZ
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bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/37668/1/license.txt
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