Caveolin-1 and Caveolin-2 Can Be Antagonistic Partners in Inflammation and Beyond

Detalhes bibliográficos
Autor(a) principal: Almeida, Cecília Jacques Gonçalves de
Data de Publicação: 2017
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/24786
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ. Brasil.
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spelling Almeida, Cecília Jacques Gonçalves de2018-02-08T16:37:41Z2018-02-08T16:37:41Z2017ALMEIDA, Cecília Jacques Gonçalves de. Caveolin-1 and Caveolin-2 Can Be Antagonistic Partners in inflammation and Beyond. Frontiers in Immunology, v.8, Article 1530, 15p, Nov. 2017.1664-3224https://www.arca.fiocruz.br/handle/icict/2478610.3389/fimmu.2017.01530engFrontiers MediaCaveolinasCavéolasInfecçãoInflamaçãoFibroseProliferaçãoendocitoseCaveolininflammationcaveolaeinfectionfibrosisproliferationendocytosissignalingCaveolin-1 and Caveolin-2 Can Be Antagonistic Partners in Inflammation and Beyondinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ. Brasil.Caveolins, encoded by the CAV gene family, are the main protein components of caveolae. In most tissues, caveolin-1 (Cav-1) and caveolin-2 (Cav-2) are co-expressed, and Cav-2 targeting to caveolae depends on the formation of heterooligomers with Cav-1. Notwithstanding, Cav-2 has unpredictable activities, opposing Cav-1 in the regulation of some cellular processes. While the major roles of Cav-1 as a modulator of cell signaling in inflammatory processes and in immune responses have been extensively discussed elsewhere, the aim of this review is to focus on data revealing the distinct activity of Cav-1 and Cav-2, which suggest that these proteins act antagonistically to fine-tune a variety of cellular processes relevant to inflammation.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/24786/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALcecilia_almeida_IOC_2017.pdfcecilia_almeida_IOC_2017.pdfapplication/pdf1525897https://www.arca.fiocruz.br/bitstream/icict/24786/2/cecilia_almeida_IOC_2017.pdf9dd840213ec34d96d8dafbba5e0d4a17MD52TEXTcecilia_almeida_IOC_2017.pdf.txtcecilia_almeida_IOC_2017.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Caveolin-1 and Caveolin-2 Can Be Antagonistic Partners in Inflammation and Beyond
title Caveolin-1 and Caveolin-2 Can Be Antagonistic Partners in Inflammation and Beyond
spellingShingle Caveolin-1 and Caveolin-2 Can Be Antagonistic Partners in Inflammation and Beyond
Almeida, Cecília Jacques Gonçalves de
Caveolinas
Cavéolas
Infecção
Inflamação
Fibrose
Proliferação
endocitose
Caveolin
inflammation
caveolae
infection
fibrosis
proliferation
endocytosis
signaling
title_short Caveolin-1 and Caveolin-2 Can Be Antagonistic Partners in Inflammation and Beyond
title_full Caveolin-1 and Caveolin-2 Can Be Antagonistic Partners in Inflammation and Beyond
title_fullStr Caveolin-1 and Caveolin-2 Can Be Antagonistic Partners in Inflammation and Beyond
title_full_unstemmed Caveolin-1 and Caveolin-2 Can Be Antagonistic Partners in Inflammation and Beyond
title_sort Caveolin-1 and Caveolin-2 Can Be Antagonistic Partners in Inflammation and Beyond
author Almeida, Cecília Jacques Gonçalves de
author_facet Almeida, Cecília Jacques Gonçalves de
author_role author
dc.contributor.author.fl_str_mv Almeida, Cecília Jacques Gonçalves de
dc.subject.other.pt_BR.fl_str_mv Caveolinas
Cavéolas
Infecção
Inflamação
Fibrose
Proliferação
endocitose
topic Caveolinas
Cavéolas
Infecção
Inflamação
Fibrose
Proliferação
endocitose
Caveolin
inflammation
caveolae
infection
fibrosis
proliferation
endocytosis
signaling
dc.subject.en.pt_BR.fl_str_mv Caveolin
inflammation
caveolae
infection
fibrosis
proliferation
endocytosis
signaling
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ. Brasil.
publishDate 2017
dc.date.issued.fl_str_mv 2017
dc.date.accessioned.fl_str_mv 2018-02-08T16:37:41Z
dc.date.available.fl_str_mv 2018-02-08T16:37:41Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv ALMEIDA, Cecília Jacques Gonçalves de. Caveolin-1 and Caveolin-2 Can Be Antagonistic Partners in inflammation and Beyond. Frontiers in Immunology, v.8, Article 1530, 15p, Nov. 2017.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/24786
dc.identifier.issn.pt_BR.fl_str_mv 1664-3224
dc.identifier.doi.none.fl_str_mv 10.3389/fimmu.2017.01530
identifier_str_mv ALMEIDA, Cecília Jacques Gonçalves de. Caveolin-1 and Caveolin-2 Can Be Antagonistic Partners in inflammation and Beyond. Frontiers in Immunology, v.8, Article 1530, 15p, Nov. 2017.
1664-3224
10.3389/fimmu.2017.01530
url https://www.arca.fiocruz.br/handle/icict/24786
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Frontiers Media
publisher.none.fl_str_mv Frontiers Media
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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