Coxiella burnetii, the agent of Q fever in Brazil: its hidden role in seronegative arthritis and the importance of molecular diagnosis based on the repetitive element IS1111 associated with the transposase gene

Detalhes bibliográficos
Autor(a) principal: Rozental, Tatiana
Data de Publicação: 2012
Outros Autores: Mascarenhas, Luis Filipe, Rozenbaum, Ronaldo, Gomes, Raphael, Mattos, Grasiely Souza, Magno, Cecília Carlos, Almeida, Daniele Nunes de, Rossi, Maria Inês Doria, Favacho, Alexsandra R. M., Lemos, Elba Regina Sampaio de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/16829
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickettsioses. Rio de Janeiro, RJ, Brasil.
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spelling Rozental, TatianaMascarenhas, Luis FilipeRozenbaum, RonaldoGomes, RaphaelMattos, Grasiely SouzaMagno, Cecília CarlosAlmeida, Daniele Nunes deRossi, Maria Inês DoriaFavacho, Alexsandra R. M.Lemos, Elba Regina Sampaio de2017-01-13T16:50:01Z2017-01-13T16:50:01Z2012ROZENTAL, Tatiana; et al. Coxiella burnetii, the agent of Q fever in Brazil: its hidden role in seronegative arthritis and the importance of molecular diagnosis based on the repetitive element IS1111 associated with the transposase gene. Mem Inst Oswaldo Cruz, v.107, n.5, p.695-697, Aug. 2012.0074-0276https://www.arca.fiocruz.br/handle/icict/168291678-8060engFundação Oswaldo Cruz. Instituto Oswaldo Cruz.Febre QLavagem BroncoalveolarAnálise molecularArtriteMetotrexatoQ feverbronchoalveolar lavagemolecular analysisseronegative polyarthritismethotrexateCoxiella burnetii, the agent of Q fever in Brazil: its hidden role in seronegative arthritis and the importance of molecular diagnosis based on the repetitive element IS1111 associated with the transposase geneinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickettsioses. Rio de Janeiro, RJ, Brasil.Hospital dos Servidores do Estado. Rio de Janeiro, RJ, Brasil.Hospital dos Servidores do Estado. Rio de Janeiro, RJ, Brasil / Hospital Samaritano. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickettsioses. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickettsioses. Rio de Janeiro, RJ, Brasil.Hospital Copa D`Or. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickettsioses. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickettsioses. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickettsioses. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickettsioses. Rio de Janeiro, RJ, Brasil.Coxiella burnetii is the agent of Q fever, an emergent worldwide zoonosis of wide clinical spectrum. Although C. burnetii infection is typically associated with acute infection, atypical pneumonia and flu-like symptoms, endocarditis, osteoarticular manifestations and severe disease are possible, especially when the patient has a suppressed immune system; however, these severe complications are typically neglected. This study reports the sequencing of the repetitive element IS1111 of the transposase gene of C. burnetii from blood and bronchoalveolar lavage (BAL) samples from a patient with severe pneumonia following methotrexate therapy, resulting in the molecular diagnosis of Q fever in a patient who had been diagnosed with active seronegative polyarthritis two years earlier. To the best of our knowledge, this represents the first documented case of the isolation of C. burnetii DNA from a BAL sample.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/16829/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALtatiana_rozenthal_etal_IOC_2012.pdftatiana_rozenthal_etal_IOC_2012.pdfapplication/pdf248091https://www.arca.fiocruz.br/bitstream/icict/16829/2/tatiana_rozenthal_etal_IOC_2012.pdf0d8179ea57f744ad8d506ddcfca5b3a4MD52TEXTtatiana_rozenthal_etal_IOC_2012.pdf.txttatiana_rozenthal_etal_IOC_2012.pdf.txtExtracted texttext/plain16627https://www.arca.fiocruz.br/bitstream/icict/16829/3/tatiana_rozenthal_etal_IOC_2012.pdf.txt0420b770d0969a9bc15d1867fd3ccfe3MD53icict/168292018-08-15 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dc.title.pt_BR.fl_str_mv Coxiella burnetii, the agent of Q fever in Brazil: its hidden role in seronegative arthritis and the importance of molecular diagnosis based on the repetitive element IS1111 associated with the transposase gene
title Coxiella burnetii, the agent of Q fever in Brazil: its hidden role in seronegative arthritis and the importance of molecular diagnosis based on the repetitive element IS1111 associated with the transposase gene
spellingShingle Coxiella burnetii, the agent of Q fever in Brazil: its hidden role in seronegative arthritis and the importance of molecular diagnosis based on the repetitive element IS1111 associated with the transposase gene
Rozental, Tatiana
Febre Q
Lavagem Broncoalveolar
Análise molecular
Artrite
Metotrexato
Q fever
bronchoalveolar lavage
molecular analysis
seronegative polyarthritis
methotrexate
title_short Coxiella burnetii, the agent of Q fever in Brazil: its hidden role in seronegative arthritis and the importance of molecular diagnosis based on the repetitive element IS1111 associated with the transposase gene
title_full Coxiella burnetii, the agent of Q fever in Brazil: its hidden role in seronegative arthritis and the importance of molecular diagnosis based on the repetitive element IS1111 associated with the transposase gene
title_fullStr Coxiella burnetii, the agent of Q fever in Brazil: its hidden role in seronegative arthritis and the importance of molecular diagnosis based on the repetitive element IS1111 associated with the transposase gene
title_full_unstemmed Coxiella burnetii, the agent of Q fever in Brazil: its hidden role in seronegative arthritis and the importance of molecular diagnosis based on the repetitive element IS1111 associated with the transposase gene
title_sort Coxiella burnetii, the agent of Q fever in Brazil: its hidden role in seronegative arthritis and the importance of molecular diagnosis based on the repetitive element IS1111 associated with the transposase gene
author Rozental, Tatiana
author_facet Rozental, Tatiana
Mascarenhas, Luis Filipe
Rozenbaum, Ronaldo
Gomes, Raphael
Mattos, Grasiely Souza
Magno, Cecília Carlos
Almeida, Daniele Nunes de
Rossi, Maria Inês Doria
Favacho, Alexsandra R. M.
Lemos, Elba Regina Sampaio de
author_role author
author2 Mascarenhas, Luis Filipe
Rozenbaum, Ronaldo
Gomes, Raphael
Mattos, Grasiely Souza
Magno, Cecília Carlos
Almeida, Daniele Nunes de
Rossi, Maria Inês Doria
Favacho, Alexsandra R. M.
Lemos, Elba Regina Sampaio de
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Rozental, Tatiana
Mascarenhas, Luis Filipe
Rozenbaum, Ronaldo
Gomes, Raphael
Mattos, Grasiely Souza
Magno, Cecília Carlos
Almeida, Daniele Nunes de
Rossi, Maria Inês Doria
Favacho, Alexsandra R. M.
Lemos, Elba Regina Sampaio de
dc.subject.other.pt_BR.fl_str_mv Febre Q
Lavagem Broncoalveolar
Análise molecular
Artrite
Metotrexato
topic Febre Q
Lavagem Broncoalveolar
Análise molecular
Artrite
Metotrexato
Q fever
bronchoalveolar lavage
molecular analysis
seronegative polyarthritis
methotrexate
dc.subject.en.pt_BR.fl_str_mv Q fever
bronchoalveolar lavage
molecular analysis
seronegative polyarthritis
methotrexate
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickettsioses. Rio de Janeiro, RJ, Brasil.
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2017-01-13T16:50:01Z
dc.date.available.fl_str_mv 2017-01-13T16:50:01Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv ROZENTAL, Tatiana; et al. Coxiella burnetii, the agent of Q fever in Brazil: its hidden role in seronegative arthritis and the importance of molecular diagnosis based on the repetitive element IS1111 associated with the transposase gene. Mem Inst Oswaldo Cruz, v.107, n.5, p.695-697, Aug. 2012.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/16829
dc.identifier.issn.pt_BR.fl_str_mv 0074-0276
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv ROZENTAL, Tatiana; et al. Coxiella burnetii, the agent of Q fever in Brazil: its hidden role in seronegative arthritis and the importance of molecular diagnosis based on the repetitive element IS1111 associated with the transposase gene. Mem Inst Oswaldo Cruz, v.107, n.5, p.695-697, Aug. 2012.
0074-0276
1678-8060
url https://www.arca.fiocruz.br/handle/icict/16829
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
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instacron_str FIOCRUZ
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