Killer immunoglobulin-like receptor (KIR) genes are associated with the risk of episodes of high-level and detectable viremia among HIV controllers [version 1; peer review: awaiting peer review]
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/48410 |
Resumo: | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil. |
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Sá, Nathalia Beatriz Ramos deSilva, Karina dos S.Alves, Marcelo RibeiroCaetano, Diogo GamaCôrtes, Fernanda HeloiseAzevedo, Suwellen S. D. deHoagland, BrendaGrinsztejn, BeatrizVeloso, Valdiléa G.Morgado, Mariza G.Teixeira, Sylvia Lopes Maia2021-07-29T19:21:58Z2021-07-29T19:21:58Z2021SÁ, Nathalia Beatriz Ramos de et al. Killer immunoglobulin-like receptor (KIR) genes are associated with the risk of episodes of high-level and detectable viremia among HIV controllers [version 1; peer review: awaiting peer review]. FI000Research, v. 10, n. 546, 18 p, July 2021.2046-1402https://www.arca.fiocruz.br/handle/icict/4841010.12688/f1000research.53683.1engControladores de HIVCarga viralAntígeno CD52InflamassomosHIV controllersViral loadHLAKIRCCR5 Δ32Inflammasome SNPsAntígeno CD52Canais de Potássio Corretores do Fluxo de InternalizaçãoKiller immunoglobulin-like receptor (KIR) genes are associated with the risk of episodes of high-level and detectable viremia among HIV controllers [version 1; peer review: awaiting peer review]info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Background: HIV controllers (HICs) constitute a heterogeneous group of HIV-1 individuals able to suppress plasma viremia to low or undetectable levels in the absence of antiretroviral therapy. Host genetic factors may be involved in the sustained control of viral replication observed. We investigated the distribution and the potential impact of human leukocyte antigens (HLA)-B and -C alleles, killer immunoglobulin-like receptor (KIR) genes, single nucleotide polymorphisms (SNPs) of the NLRP3, CARD8 and IL-1β inflammasome genes, and CCR5Δ32 mutation on the viral control among HICs.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/48410/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALNataliaB_Ramos_etal_IOC_2021.pdfNataliaB_Ramos_etal_IOC_2021.pdfapplication/pdf345857https://www.arca.fiocruz.br/bitstream/icict/48410/2/NataliaB_Ramos_etal_IOC_2021.pdf1ef22e25970546d27cdc07e7adb38156MD52TEXTNataliaB_Ramos_etal_IOC_2021.pdf.txtNataliaB_Ramos_etal_IOC_2021.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv |
Killer immunoglobulin-like receptor (KIR) genes are associated with the risk of episodes of high-level and detectable viremia among HIV controllers [version 1; peer review: awaiting peer review] |
title |
Killer immunoglobulin-like receptor (KIR) genes are associated with the risk of episodes of high-level and detectable viremia among HIV controllers [version 1; peer review: awaiting peer review] |
spellingShingle |
Killer immunoglobulin-like receptor (KIR) genes are associated with the risk of episodes of high-level and detectable viremia among HIV controllers [version 1; peer review: awaiting peer review] Sá, Nathalia Beatriz Ramos de Controladores de HIV Carga viral Antígeno CD52 Inflamassomos HIV controllers Viral load HLA KIR CCR5 Δ32 Inflammasome SNPs Antígeno CD52 Canais de Potássio Corretores do Fluxo de Internalização |
title_short |
Killer immunoglobulin-like receptor (KIR) genes are associated with the risk of episodes of high-level and detectable viremia among HIV controllers [version 1; peer review: awaiting peer review] |
title_full |
Killer immunoglobulin-like receptor (KIR) genes are associated with the risk of episodes of high-level and detectable viremia among HIV controllers [version 1; peer review: awaiting peer review] |
title_fullStr |
Killer immunoglobulin-like receptor (KIR) genes are associated with the risk of episodes of high-level and detectable viremia among HIV controllers [version 1; peer review: awaiting peer review] |
title_full_unstemmed |
Killer immunoglobulin-like receptor (KIR) genes are associated with the risk of episodes of high-level and detectable viremia among HIV controllers [version 1; peer review: awaiting peer review] |
title_sort |
Killer immunoglobulin-like receptor (KIR) genes are associated with the risk of episodes of high-level and detectable viremia among HIV controllers [version 1; peer review: awaiting peer review] |
author |
Sá, Nathalia Beatriz Ramos de |
author_facet |
Sá, Nathalia Beatriz Ramos de Silva, Karina dos S. Alves, Marcelo Ribeiro Caetano, Diogo Gama Côrtes, Fernanda Heloise Azevedo, Suwellen S. D. de Hoagland, Brenda Grinsztejn, Beatriz Veloso, Valdiléa G. Morgado, Mariza G. Teixeira, Sylvia Lopes Maia |
author_role |
author |
author2 |
Silva, Karina dos S. Alves, Marcelo Ribeiro Caetano, Diogo Gama Côrtes, Fernanda Heloise Azevedo, Suwellen S. D. de Hoagland, Brenda Grinsztejn, Beatriz Veloso, Valdiléa G. Morgado, Mariza G. Teixeira, Sylvia Lopes Maia |
author2_role |
author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Sá, Nathalia Beatriz Ramos de Silva, Karina dos S. Alves, Marcelo Ribeiro Caetano, Diogo Gama Côrtes, Fernanda Heloise Azevedo, Suwellen S. D. de Hoagland, Brenda Grinsztejn, Beatriz Veloso, Valdiléa G. Morgado, Mariza G. Teixeira, Sylvia Lopes Maia |
dc.subject.other.pt_BR.fl_str_mv |
Controladores de HIV Carga viral Antígeno CD52 Inflamassomos |
topic |
Controladores de HIV Carga viral Antígeno CD52 Inflamassomos HIV controllers Viral load HLA KIR CCR5 Δ32 Inflammasome SNPs Antígeno CD52 Canais de Potássio Corretores do Fluxo de Internalização |
dc.subject.en.pt_BR.fl_str_mv |
HIV controllers Viral load HLA KIR CCR5 Δ32 Inflammasome SNPs |
dc.subject.decs.pt_BR.fl_str_mv |
Antígeno CD52 Canais de Potássio Corretores do Fluxo de Internalização |
description |
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil. |
publishDate |
2021 |
dc.date.accessioned.fl_str_mv |
2021-07-29T19:21:58Z |
dc.date.available.fl_str_mv |
2021-07-29T19:21:58Z |
dc.date.issued.fl_str_mv |
2021 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
SÁ, Nathalia Beatriz Ramos de et al. Killer immunoglobulin-like receptor (KIR) genes are associated with the risk of episodes of high-level and detectable viremia among HIV controllers [version 1; peer review: awaiting peer review]. FI000Research, v. 10, n. 546, 18 p, July 2021. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/48410 |
dc.identifier.issn.pt_BR.fl_str_mv |
2046-1402 |
dc.identifier.doi.none.fl_str_mv |
10.12688/f1000research.53683.1 |
identifier_str_mv |
SÁ, Nathalia Beatriz Ramos de et al. Killer immunoglobulin-like receptor (KIR) genes are associated with the risk of episodes of high-level and detectable viremia among HIV controllers [version 1; peer review: awaiting peer review]. FI000Research, v. 10, n. 546, 18 p, July 2021. 2046-1402 10.12688/f1000research.53683.1 |
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https://www.arca.fiocruz.br/handle/icict/48410 |
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eng |
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