Case report: SARS-CoV-2 mother-to-child transmission and fetal death associated with severe placental thromboembolism

Detalhes bibliográficos
Autor(a) principal: Marinho, Penélope Saldanha
Data de Publicação: 2021
Outros Autores: Cunha, Antonio José Ledo Alves da, Chimelli, Leila, Avvad-Portari, Elyzabeth, Andreiuolo, Felipe da Matta, Oliveira-Szejnfeld, Patrícia Soares de, Mendes, Mayara Abud, Gomes, Ismael Carlos, Souza, Letícia Rocha Q., Guimarães, Marilia Zaluar, Goldman, Suzan Menasce, Oliveira, Mariana Barros Genuíno de, Rehen, Stevens, Amim Jr., Joffre, Tovar-Moll, Fernanda, Prata-Barbosa, Arnaldo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/49129
Resumo: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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spelling Marinho, Penélope SaldanhaCunha, Antonio José Ledo Alves daChimelli, LeilaAvvad-Portari, ElyzabethAndreiuolo, Felipe da MattaOliveira-Szejnfeld, Patrícia Soares deMendes, Mayara AbudGomes, Ismael CarlosSouza, Letícia Rocha Q.Guimarães, Marilia ZaluarGoldman, Suzan MenasceOliveira, Mariana Barros Genuíno deRehen, StevensAmim Jr., JoffreTovar-Moll, FernandaPrata-Barbosa, Arnaldo2021-09-22T11:53:38Z2021-09-22T11:53:38Z2021MARINHO, Penélope Saldanha et al. Case report: SARS-CoV-2 mother-to-child transmission and fetal death associated with severe placental thromboembolism. Frontiers in Medicine, v. 8, n. 677001, p. 1-9, 16 Aug. 2021.2296-858Xhttps://www.arca.fiocruz.br/handle/icict/4912910.3389/fmed.2021.6770012296-858XThe authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.Universidade Federal do Rio de Janeiro. Centro de Ciências da Saúde. Maternidade Escola. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Centro de Ciências da Saúde. Maternidade Escola. Rio de Janeiro, RJ, Brasil / Instituto D'Or de Pesquisa e Ensino. Departamento de Pediatria. Rio de Janeiro, RJ, Brasil.Instituto Estadual do Cérebro Paulo Niemeyer. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira. Departamento de Anatomia Patológica. Rio de Janeiro, RJ, Brasil / Universidade Estadual do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.Instituto Estadual do Cérebro Paulo Niemeyer. Rio de Janeiro, RJ, Brasil.Universidade Federal de São Paulo. Escola Paulista de Medicina. São Paulo, SP, Brasil / Instituto D'Or de Pesquisa e Ensino. Departamento de Pediatria. Rio de Janeiro, RJ, Brasil.Instituto D'Or de Pesquisa e Ensino. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Rio de Janeiro, RJ, Brasil / Hospital Jesus. Rio de Janeiro, RJ, Brasil.Instituto D'Or de Pesquisa e Ensino. Rio de Janeiro, RJ, Brasil.Instituto D'Or de Pesquisa e Ensino. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Centro de Ciências da Saúde. Maternidade Escola. Rio de Janeiro, RJ, Brasil.Universidade Federal de São Paulo. Escola Paulista de Medicina. São Paulo, SP, Brasil.Instituto D'Or de Pesquisa e Ensino. Departamento de Pediatria. Rio de Janeiro, RJ, Brasil.Instituto D'Or de Pesquisa e Ensino. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Centro de Ciências da Saúde. Maternidade Escola. Rio de Janeiro, RJ, Brasil.Universidade Federal de São Paulo. Escola Paulista de Medicina. São Paulo, SP, Brasil / Instituto D'Or de Pesquisa e Ensino. Departamento de Pediatria. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Centro de Ciências da Saúde. Maternidade Escola. Rio de Janeiro, RJ, Brasil / Instituto D'Or de Pesquisa e Ensino. Rio de Janeiro, RJ, Brasil.SARS-CoV-2 infection during pregnancy is not usually associated with significant adverse effects. However, in this study, we report a fetal death associated with mild COVID-19 in a 34-week-pregnant woman. The virus was detected in the placenta and in an unprecedented way in several fetal tissues. Placental abnormalities (MRI and anatomopathological study) were consistent with intense vascular malperfusion, probably the cause of fetal death. Lung histopathology also showed signs of inflammation, which could have been a contributory factor. Monitoring inflammatory response and coagulation in high-risk pregnant women with COVID-19 may prevent unfavorable outcomes, as shown in this case.engFrontiers MediaCase report: SARS-CoV-2 mother-to-child transmission and fetal death associated with severe placental thromboembolisminfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleSARS-CoV-2COVID-19PregnancyFetal deathPlacental thromboembolismMother-to-child transmissioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/49129/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALve_Elyzabeth_Avvad-Portari_etal_IFF_2021.pdfve_Elyzabeth_Avvad-Portari_etal_IFF_2021.pdfapplication/pdf2505966https://www.arca.fiocruz.br/bitstream/icict/49129/2/ve_Elyzabeth_Avvad-Portari_etal_IFF_2021.pdfee4b22c4d0e1e94e32d70dc790df300fMD52Table_1_Case Report_ SARS-CoV-2 Mother-to-Child Transmission and Fetal Death Associated With Severe Placental Thromboembolism.DOCXTable_1_Case Report_ SARS-CoV-2 Mother-to-Child Transmission and Fetal Death Associated With Severe Placental Thromboembolism.DOCXSupplementary Materialapplication/vnd.openxmlformats-officedocument.wordprocessingml.document5197748https://www.arca.fiocruz.br/bitstream/icict/49129/3/Table_1_Case%20Report_%20SARS-CoV-2%20Mother-to-Child%20Transmission%20and%20Fetal%20Death%20Associated%20With%20Severe%20Placental%20Thromboembolism.DOCXd8448bd33e9d14e2d28c9d8f7e88b6dcMD53icict/491292021-09-22 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dc.title.pt_BR.fl_str_mv Case report: SARS-CoV-2 mother-to-child transmission and fetal death associated with severe placental thromboembolism
title Case report: SARS-CoV-2 mother-to-child transmission and fetal death associated with severe placental thromboembolism
spellingShingle Case report: SARS-CoV-2 mother-to-child transmission and fetal death associated with severe placental thromboembolism
Marinho, Penélope Saldanha
SARS-CoV-2
COVID-19
Pregnancy
Fetal death
Placental thromboembolism
Mother-to-child transmission
title_short Case report: SARS-CoV-2 mother-to-child transmission and fetal death associated with severe placental thromboembolism
title_full Case report: SARS-CoV-2 mother-to-child transmission and fetal death associated with severe placental thromboembolism
title_fullStr Case report: SARS-CoV-2 mother-to-child transmission and fetal death associated with severe placental thromboembolism
title_full_unstemmed Case report: SARS-CoV-2 mother-to-child transmission and fetal death associated with severe placental thromboembolism
title_sort Case report: SARS-CoV-2 mother-to-child transmission and fetal death associated with severe placental thromboembolism
author Marinho, Penélope Saldanha
author_facet Marinho, Penélope Saldanha
Cunha, Antonio José Ledo Alves da
Chimelli, Leila
Avvad-Portari, Elyzabeth
Andreiuolo, Felipe da Matta
Oliveira-Szejnfeld, Patrícia Soares de
Mendes, Mayara Abud
Gomes, Ismael Carlos
Souza, Letícia Rocha Q.
Guimarães, Marilia Zaluar
Goldman, Suzan Menasce
Oliveira, Mariana Barros Genuíno de
Rehen, Stevens
Amim Jr., Joffre
Tovar-Moll, Fernanda
Prata-Barbosa, Arnaldo
author_role author
author2 Cunha, Antonio José Ledo Alves da
Chimelli, Leila
Avvad-Portari, Elyzabeth
Andreiuolo, Felipe da Matta
Oliveira-Szejnfeld, Patrícia Soares de
Mendes, Mayara Abud
Gomes, Ismael Carlos
Souza, Letícia Rocha Q.
Guimarães, Marilia Zaluar
Goldman, Suzan Menasce
Oliveira, Mariana Barros Genuíno de
Rehen, Stevens
Amim Jr., Joffre
Tovar-Moll, Fernanda
Prata-Barbosa, Arnaldo
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Marinho, Penélope Saldanha
Cunha, Antonio José Ledo Alves da
Chimelli, Leila
Avvad-Portari, Elyzabeth
Andreiuolo, Felipe da Matta
Oliveira-Szejnfeld, Patrícia Soares de
Mendes, Mayara Abud
Gomes, Ismael Carlos
Souza, Letícia Rocha Q.
Guimarães, Marilia Zaluar
Goldman, Suzan Menasce
Oliveira, Mariana Barros Genuíno de
Rehen, Stevens
Amim Jr., Joffre
Tovar-Moll, Fernanda
Prata-Barbosa, Arnaldo
dc.subject.en.en.fl_str_mv SARS-CoV-2
COVID-19
Pregnancy
Fetal death
Placental thromboembolism
Mother-to-child transmission
topic SARS-CoV-2
COVID-19
Pregnancy
Fetal death
Placental thromboembolism
Mother-to-child transmission
description The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
publishDate 2021
dc.date.accessioned.fl_str_mv 2021-09-22T11:53:38Z
dc.date.available.fl_str_mv 2021-09-22T11:53:38Z
dc.date.issued.fl_str_mv 2021
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv MARINHO, Penélope Saldanha et al. Case report: SARS-CoV-2 mother-to-child transmission and fetal death associated with severe placental thromboembolism. Frontiers in Medicine, v. 8, n. 677001, p. 1-9, 16 Aug. 2021.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/49129
dc.identifier.issn.pt_BR.fl_str_mv 2296-858X
dc.identifier.doi.pt_BR.fl_str_mv 10.3389/fmed.2021.677001
dc.identifier.eissn.pt_BR.fl_str_mv 2296-858X
identifier_str_mv MARINHO, Penélope Saldanha et al. Case report: SARS-CoV-2 mother-to-child transmission and fetal death associated with severe placental thromboembolism. Frontiers in Medicine, v. 8, n. 677001, p. 1-9, 16 Aug. 2021.
2296-858X
10.3389/fmed.2021.677001
url https://www.arca.fiocruz.br/handle/icict/49129
dc.language.iso.fl_str_mv eng
language eng
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dc.publisher.none.fl_str_mv Frontiers Media
publisher.none.fl_str_mv Frontiers Media
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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