Phylogeography and Genetic Variation of Triatoma dimidiata, the Main Chagas Disease Vector in Central America, and Its Position within the Genus Triatoma

Detalhes bibliográficos
Autor(a) principal: Bargues, María Dolores
Data de Publicação: 2008
Outros Autores: Klisiowicz, Debora R., Gonzalez-Candelas, Fernando, Ramsey, Janine M., Monroy, Carlota, Ponce, Carlos, Salazar-Schettino, Paz María, Panzera, Francisco, Abad-Franch, Fernando, Sousa, Octavio E., Schofield, Christopher J., Dujardin, Jean Pierre, Guhl, Felipe, Mas-Coma, Santiago
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/1928
Resumo: Facultad de Farmacia, Universidad de Valencia. Departamento de Parasitologia, Burjassot, Valencia, Spain
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spelling Bargues, María DoloresKlisiowicz, Debora R.Gonzalez-Candelas, FernandoRamsey, Janine M.Monroy, CarlotaPonce, CarlosSalazar-Schettino, Paz MaríaPanzera, FranciscoAbad-Franch, FernandoSousa, Octavio E.Schofield, Christopher J.Dujardin, Jean PierreGuhl, FelipeMas-Coma, Santiago2011-04-21T15:19:31Z2011-04-21T15:19:31Z2008BARQUES, María Dolores et al. Phylogeography and Genetic Variation of Triatoma dimidiata, the Main Chagas Disease Vector in Central America, and Its Position within the Genus Triatoma. PLoS Neglected Tropical Diseases, v. 2, n. 5, p. 233, p. 1-19, 2008.https://www.arca.fiocruz.br/handle/icict/192810.1371/journal.pntd.0000233engPhylogeography and Genetic Variation of Triatoma dimidiata, the Main Chagas Disease Vector in Central America, and Its Position within the Genus Triatomainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFacultad de Farmacia, Universidad de Valencia. Departamento de Parasitologia, Burjassot, Valencia, SpainUniversidad de Valencia. Facultad de Farmacia. Departamento de Parasitologia. Valencia, Spain.Universidad de Valencia. Departamento de Genética. Instituto Cavanilles de Biodiversidad y Biologia Evolutiva. Valencia, Spain.Instituto Nacional de Salud Pública. Centro Regional de Investigación en Salud Pública. Tapachula, Chiapas, México.Universidad San Carlos. Laboratorio de Entomologia Aplicada y Parasitologia. Guatemala.Secretaria de Salud. Laboratorio Central de Referencia para Enfermedad de Chagas y Leishmaniasis. Tegucigalpa, Honduras.Facultad de Medicina. Laboratorio Biología de Parásitos. Departamento de Microbiología y Parasitologıía. México D.F., México.Instituto Nacional de Salud Pública. Centro de Investigaciones sobre Enfermedades Infecciosas. Cuernavaca, Morelos, México.Fundação Oswaldo Cruz. Centro de Pesquisa Leônidas & Maria Deane. Biodiversity Laboratory–Medical Entomology. Manaus, AM, Brazil.University of Panama. Faculty of Medicine. Center for Research and Diagnosis of Parasitic Diseases. Panama City, Republic of PanamaLondon School of Hygiene and Tropical Medicine. Department of Infectious and Tropical Diseases London. United Kingdom.Institut de Recherche pour le Developpement., Representative Office, French Embassy, Bangkok, Thailand.Universidad de los Andes. Facultad de Ciencias. Centro de Investigaciones em Microbiología y Parasitología Tropical. Bogotá, Colombia.Facultad de Farmacia, Universidad de Valencia. Departamento de Parasitologia. Burjassot, Valencia, Spain.Background: Among Chagas disease triatomine vectors, the largest genus, Triatoma, includes species of high public health interest. Triatoma dimidiata, the main vector throughout Central America and up to Ecuador, presents extensive phenotypic, genotypic, and behavioral diversity in sylvatic, peridomestic and domestic habitats, and non-domiciliated populations acting as reinfestation sources. DNA sequence analyses, phylogenetic reconstruction methods, and genetic variation approaches are combined to investigate the haplotype profiling, genetic polymorphism, phylogeography, and evolutionary trends of T. dimidiata and its closest relatives within Triatoma. This is the largest interpopulational analysis performed on a triatomine species so far. Methodology and Findings: Triatomines from Mexico, Guatemala, Honduras, Nicaragua, Panama, Cuba, Colombia, Ecuador, and Brazil were used. Triatoma dimidiata populations follow different evolutionary divergences in which geographical isolation appears to have had an important influence. A southern Mexican–northern Guatemalan ancestral form gave rise to two main clades. One clade remained confined to the Yucatan peninsula and northern parts of Chiapas State, Guatemala, and Honduras, with extant descendants deserving specific status.Within the second clade, extant subspecies diversity was shaped by adaptive radiation derived from Guatemalan ancestral populations. Central American populations correspond to subspecies T. d. dimidiata. A southern spread into Panama and Colombia gave the T. d. capitata forms, and a northwestern spread rising from Guatemala into Mexico gave the T. d. maculipennis forms. Triatoma hegneri appears as a subspecific insular form. Conclusions: The comparison with very numerous Triatoma species allows us to reach highly supported conclusions not only about T. dimidiata, but also on different, important Triatoma species groupings and their evolution. The very large intraspecific genetic variability found in T. dimidiata sensu lato has never been detected in a triatomine species before. The distinction between the five different taxa furnishes a new frame for future analyses of the different vector transmission capacities and epidemiological characteristics of Chagas disease. Results indicate that T. dimidiata will offer problems for control, although dwelling insecticide spraying might be successful against introduced populations in Ecuador.Chagas DiseaseChagas Disease VectorGenus TriatomaTriatoma DimidiataPhylogeographyTriatominesThis work benefited from international collaboration through the ECLAT network. Financial support for DNA sequencing was obtained from the Projects ‘‘Chagas Disease Intervention Activities’’ (CDIA, Contract No. ICA4CT-2003-10049) and ‘‘European Commission Latin America Triatominae Network’’ (ECLAT, Contract No. IC18-CT98-0366) of the INCO-DEV and INCO-DC Programs of the European Commission (DG XII), Brussels, Belgium, Project No. 3042/2000 of the Direccio´n General de Cooperacio´n para el Desarrollo, Presidencia de Gobierno, Generalitat Valenciana, Valencia, Spain, and the Red de Investigacio´n de Centros de Enfermedades Tropicales - RICET (Projects No. C03/04, No. PI030545 and No. RD06/0021/0017 of the Program of Redes Tema´ticas de Investigacio´n Cooperativa), FIS, Spanish Ministry of Health, Madrid, Spain. F. Panzera benefited from funding by the Conselleria de Cultura i Educacio´ of the Valencian regional government, Spain and the University of Valencia for two working stays at the Parasitology Department of Valencia, as well as from Comisio´n Sectorial de Investigacio´n Cientı´fica (CSIC), Uruguay, for sample collections. F. Guhl benefited from funding by the University of Valencia for a 6-month research stay at the Parasitology Department of Valencia. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscriptinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALPhylogeography and Genetic.pdfPhylogeography and Genetic.pdfapplication/pdf575868https://www.arca.fiocruz.br/bitstream/icict/1928/1/Phylogeography%20and%20Genetic.pdf2c98cb4cae9ec6f7f370dd37f49b2032MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81648https://www.arca.fiocruz.br/bitstream/icict/1928/2/license.txte095249ac7cacefbfe39684dfe45e706MD52TEXTPhylogeography and Genetic.pdf.txtPhylogeography and Genetic.pdf.txtExtracted texttext/plain96380https://www.arca.fiocruz.br/bitstream/icict/1928/5/Phylogeography%20and%20Genetic.pdf.txt17637088cb1d64de7959143b88fea320MD55THUMBNAILPhylogeography and Genetic.pdf.jpgPhylogeography and Genetic.pdf.jpgGenerated Thumbnailimage/jpeg2170https://www.arca.fiocruz.br/bitstream/icict/1928/4/Phylogeography%20and%20Genetic.pdf.jpg608a793f021f110c779c42ed8e1127ceMD54icict/19282018-06-12 15:45:58.784oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352018-06-12T18:45:58Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Phylogeography and Genetic Variation of Triatoma dimidiata, the Main Chagas Disease Vector in Central America, and Its Position within the Genus Triatoma
title Phylogeography and Genetic Variation of Triatoma dimidiata, the Main Chagas Disease Vector in Central America, and Its Position within the Genus Triatoma
spellingShingle Phylogeography and Genetic Variation of Triatoma dimidiata, the Main Chagas Disease Vector in Central America, and Its Position within the Genus Triatoma
Bargues, María Dolores
Chagas Disease
Chagas Disease Vector
Genus Triatoma
Triatoma Dimidiata
Phylogeography
Triatomines
title_short Phylogeography and Genetic Variation of Triatoma dimidiata, the Main Chagas Disease Vector in Central America, and Its Position within the Genus Triatoma
title_full Phylogeography and Genetic Variation of Triatoma dimidiata, the Main Chagas Disease Vector in Central America, and Its Position within the Genus Triatoma
title_fullStr Phylogeography and Genetic Variation of Triatoma dimidiata, the Main Chagas Disease Vector in Central America, and Its Position within the Genus Triatoma
title_full_unstemmed Phylogeography and Genetic Variation of Triatoma dimidiata, the Main Chagas Disease Vector in Central America, and Its Position within the Genus Triatoma
title_sort Phylogeography and Genetic Variation of Triatoma dimidiata, the Main Chagas Disease Vector in Central America, and Its Position within the Genus Triatoma
author Bargues, María Dolores
author_facet Bargues, María Dolores
Klisiowicz, Debora R.
Gonzalez-Candelas, Fernando
Ramsey, Janine M.
Monroy, Carlota
Ponce, Carlos
Salazar-Schettino, Paz María
Panzera, Francisco
Abad-Franch, Fernando
Sousa, Octavio E.
Schofield, Christopher J.
Dujardin, Jean Pierre
Guhl, Felipe
Mas-Coma, Santiago
author_role author
author2 Klisiowicz, Debora R.
Gonzalez-Candelas, Fernando
Ramsey, Janine M.
Monroy, Carlota
Ponce, Carlos
Salazar-Schettino, Paz María
Panzera, Francisco
Abad-Franch, Fernando
Sousa, Octavio E.
Schofield, Christopher J.
Dujardin, Jean Pierre
Guhl, Felipe
Mas-Coma, Santiago
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Bargues, María Dolores
Klisiowicz, Debora R.
Gonzalez-Candelas, Fernando
Ramsey, Janine M.
Monroy, Carlota
Ponce, Carlos
Salazar-Schettino, Paz María
Panzera, Francisco
Abad-Franch, Fernando
Sousa, Octavio E.
Schofield, Christopher J.
Dujardin, Jean Pierre
Guhl, Felipe
Mas-Coma, Santiago
dc.subject.en.pt_BR.fl_str_mv Chagas Disease
Chagas Disease Vector
Genus Triatoma
Triatoma Dimidiata
Phylogeography
topic Chagas Disease
Chagas Disease Vector
Genus Triatoma
Triatoma Dimidiata
Phylogeography
Triatomines
dc.subject.es.pt_BR.fl_str_mv Triatomines
description Facultad de Farmacia, Universidad de Valencia. Departamento de Parasitologia, Burjassot, Valencia, Spain
publishDate 2008
dc.date.issued.fl_str_mv 2008
dc.date.accessioned.fl_str_mv 2011-04-21T15:19:31Z
dc.date.available.fl_str_mv 2011-04-21T15:19:31Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv BARQUES, María Dolores et al. Phylogeography and Genetic Variation of Triatoma dimidiata, the Main Chagas Disease Vector in Central America, and Its Position within the Genus Triatoma. PLoS Neglected Tropical Diseases, v. 2, n. 5, p. 233, p. 1-19, 2008.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/1928
dc.identifier.doi.none.fl_str_mv 10.1371/journal.pntd.0000233
identifier_str_mv BARQUES, María Dolores et al. Phylogeography and Genetic Variation of Triatoma dimidiata, the Main Chagas Disease Vector in Central America, and Its Position within the Genus Triatoma. PLoS Neglected Tropical Diseases, v. 2, n. 5, p. 233, p. 1-19, 2008.
10.1371/journal.pntd.0000233
url https://www.arca.fiocruz.br/handle/icict/1928
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
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instacron_str FIOCRUZ
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collection Repositório Institucional da FIOCRUZ (ARCA)
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