Teratogenic effects of the Zika virus and the role of the placenta

Detalhes bibliográficos
Autor(a) principal: Adibi, Jennifer J.
Data de Publicação: 2016
Outros Autores: Marques Júnior, Ernesto Torres de Azevedo, Cartus, Abigail, Beigi, Richard H.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/13657
Resumo: Artigo liberado em acesso aberto como parte do acordo para tornar público todos os dados produzidos sobre o vírus zika - Compartilhamento de dados em emergências de saúde pública - http://www.wellcome.ac.uk/News/Media-office/Press-releases/2016/WTP060169.htm
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spelling Adibi, Jennifer J.Marques Júnior, Ernesto Torres de AzevedoCartus, AbigailBeigi, Richard H.2016-04-08T12:50:07Z2016-04-08T12:50:07Z2016ADIBI, Jennifer J.; MARQUES JUNIOR, Ernesto Torres de Azevedo; CARTUS, Abigail; BEIGI, Richard H. Teratogenic effects of the Zika virus and the role of the placenta. The Lancet, New York, p. 2-4, 4 Mar. 2016. Disponível em: <http://thelancet.com/pdfs/journals/lancet/PIIS0140-6736(16)00650-4.pdf>. Acesso em: 04 abr. 2016.0140-6736https://www.arca.fiocruz.br/handle/icict/1365710.1016/S0140-6736(16)00650-4Artigo liberado em acesso aberto como parte do acordo para tornar público todos os dados produzidos sobre o vírus zika - Compartilhamento de dados em emergências de saúde pública - http://www.wellcome.ac.uk/News/Media-office/Press-releases/2016/WTP060169.htmDepartment of Epidemiology, Graduate School of Public Health. University of Pittsburgh. Pittsburgh, PA, USA / Department of Obstetrics and Gynecology and Reproductive Sciences. University of Pittsburgh. Pittsburgh, PA, USA.Center for Vaccine Research. University of Pittsburgh, Pittsburgh, PA, USA / Fundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Recife, PE, Brasil.Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Sciences Center. Houston, Texas, USA.Department of Obstetrics and Gynecology and Reproductive Sciences. University of Pittsburgh. Pittsburgh, PA, USA.The mechanism by which the Zika virus can cause fetal microcephaly is not known. Reports indicate that Zika is able to evade the normal immunoprotective responses of the placenta. Microcephaly has genetic causes, some associated with maternal exposures including radiation, tobacco smoke, alcohol, and viruses. Two hypotheses regarding the role of the placenta are possible: one is that the placenta directly conveys the Zika virus to the early embryo or fetus. Alternatively, the placenta itself might be mounting a response to the exposure; this response might be contributing to or causing the brain defect. This distinction is crucial to the diagnosis of fetuses at risk and the design of therapeutic strategies to prevent Zika-induced teratogenesis.engElsevierZika vírusMicrocefaliaEpidemiaZikaZika VirusMicrocephalyPerigos TeratogênicosZika virusEpidemicTeratogenic effects of the Zika virus and the role of the placentainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/13657/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALTeratogenic effects of the Zika virus and the role of the placenta.pdfTeratogenic effects of the Zika virus and the role of the 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dc.title.pt_BR.fl_str_mv Teratogenic effects of the Zika virus and the role of the placenta
title Teratogenic effects of the Zika virus and the role of the placenta
spellingShingle Teratogenic effects of the Zika virus and the role of the placenta
Adibi, Jennifer J.
Zika vírus
Microcefalia
Epidemia
Zika
Zika Virus
Microcephaly
Perigos Teratogênicos
Zika virus
Epidemic
title_short Teratogenic effects of the Zika virus and the role of the placenta
title_full Teratogenic effects of the Zika virus and the role of the placenta
title_fullStr Teratogenic effects of the Zika virus and the role of the placenta
title_full_unstemmed Teratogenic effects of the Zika virus and the role of the placenta
title_sort Teratogenic effects of the Zika virus and the role of the placenta
author Adibi, Jennifer J.
author_facet Adibi, Jennifer J.
Marques Júnior, Ernesto Torres de Azevedo
Cartus, Abigail
Beigi, Richard H.
author_role author
author2 Marques Júnior, Ernesto Torres de Azevedo
Cartus, Abigail
Beigi, Richard H.
author2_role author
author
author
dc.contributor.author.fl_str_mv Adibi, Jennifer J.
Marques Júnior, Ernesto Torres de Azevedo
Cartus, Abigail
Beigi, Richard H.
dc.subject.other.pt_BR.fl_str_mv Zika vírus
Microcefalia
Epidemia
Zika
topic Zika vírus
Microcefalia
Epidemia
Zika
Zika Virus
Microcephaly
Perigos Teratogênicos
Zika virus
Epidemic
dc.subject.en.pt_BR.fl_str_mv Zika Virus
Microcephaly
dc.subject.decs.pt_BR.fl_str_mv Perigos Teratogênicos
Zika virus
Epidemic
description Artigo liberado em acesso aberto como parte do acordo para tornar público todos os dados produzidos sobre o vírus zika - Compartilhamento de dados em emergências de saúde pública - http://www.wellcome.ac.uk/News/Media-office/Press-releases/2016/WTP060169.htm
publishDate 2016
dc.date.accessioned.fl_str_mv 2016-04-08T12:50:07Z
dc.date.available.fl_str_mv 2016-04-08T12:50:07Z
dc.date.issued.fl_str_mv 2016
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv ADIBI, Jennifer J.; MARQUES JUNIOR, Ernesto Torres de Azevedo; CARTUS, Abigail; BEIGI, Richard H. Teratogenic effects of the Zika virus and the role of the placenta. The Lancet, New York, p. 2-4, 4 Mar. 2016. Disponível em: <http://thelancet.com/pdfs/journals/lancet/PIIS0140-6736(16)00650-4.pdf>. Acesso em: 04 abr. 2016.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/13657
dc.identifier.issn.none.fl_str_mv 0140-6736
dc.identifier.doi.none.fl_str_mv 10.1016/S0140-6736(16)00650-4
identifier_str_mv ADIBI, Jennifer J.; MARQUES JUNIOR, Ernesto Torres de Azevedo; CARTUS, Abigail; BEIGI, Richard H. Teratogenic effects of the Zika virus and the role of the placenta. The Lancet, New York, p. 2-4, 4 Mar. 2016. Disponível em: <http://thelancet.com/pdfs/journals/lancet/PIIS0140-6736(16)00650-4.pdf>. Acesso em: 04 abr. 2016.
0140-6736
10.1016/S0140-6736(16)00650-4
url https://www.arca.fiocruz.br/handle/icict/13657
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
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