Quantification through TLC-Densitometric analysis, repellency and anticholinesterase activity of the homemade extract of Indian cloves

Detalhes bibliográficos
Autor(a) principal: Affonso, Raphael
Data de Publicação: 2017
Outros Autores: Lima, Josélia, Lessa, Bruno, Caetano, João, Obara, Marcos, Nóbrega, Andrea, Nepominova, Eugenie, Musilek, Kamil, Kuca, Kamil, Slana, Gláucia Barbosa Candido Alves, França, Tanos
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/22816
Resumo: Instituto Militar de Engenharia. Modelagem Aplicada à Defesa Química e Biológica. Rio de Janeiro, RJ, Brasil.
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spelling Affonso, RaphaelLima, JoséliaLessa, BrunoCaetano, JoãoObara, MarcosNóbrega, AndreaNepominova, EugenieMusilek, KamilKuca, KamilSlana, Gláucia Barbosa Candido AlvesFrança, Tanos2017-10-10T14:37:23Z2017-10-10T14:37:23Z2017AFFONSO, Raphael. Quantification through TLC-Densitometric analysis, repellency and anticholinesterase activity of the homemade extract of Indian cloves. Biomed Chromatogr, Sep 2017.https://www.arca.fiocruz.br/handle/icict/2281610.1002/bmc.4096porSyzygium Aromaticum L.Repelente de InsetosEugenolAnti-ColinesteraseAedes AegyptiSyzygium Aromaticum L.Insect RepellentEugenolAnticholinesteraseAedes AegyptiQuantification through TLC-Densitometric analysis, repellency and anticholinesterase activity of the homemade extract of Indian clovesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleInstituto Militar de Engenharia. Modelagem Aplicada à Defesa Química e Biológica. Rio de Janeiro, RJ, Brasil.Instituto Militar de Engenharia. Modelagem Aplicada à Defesa Química e Biológica. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Plataforma Agroecológica de Fitomedicina. Laboratório de Química da Biodiversidade. Rio de Janeiro, RJ, Brasil.Anhanguera College of Brasília. Brasília, Brasil.Universidade de Brasília. Núcleo de medicina tropical. Brasília, Brasil.Fundação Oswaldo Cruz. Plataforma Agroecológica de Fitomedicina. Laboratório de Química da Biodiversidade. Rio de Janeiro, RJ, Brasil.Hospital Universitário Hradec Kralove. Biomedical Research Center. Hradec Kralove, República Tcheca.Hospital Universitário Hradec Kralove. Biomedical Research Center. Hradec Kralove, República Tcheca.Hospital Universitário Hradec Kralove. Biomedical Research Center. Hradec Kralove, República Tcheca / Universidade da Defesa. Faculdade de Ciências da Saúde Militares. Departamento de Toxicologia e Farmácia Militar. Hradec Kralove, República TchecaFundação Oswaldo Cruz. Plataforma Agroecológica de Fitomedicina. Laboratório de Química da Biodiversidade. Rio de Janeiro, RJ, Brasil / Instituto Nacional de Propriedade Intelectual. Rio de Janeiro, RJ, Brasil.Instituto Militar de Engenharia. Modelagem Aplicada à Defesa Química e Biológica. Rio de Janeiro, RJ, Brasil / Universidade de Hradec Kralove. Faculdade de Informática e Gestão. Centro para Pesquisa Básica e Aplicada. Hradec Kralove, República Tcheca.The rise of mosquito’s transmitted diseases, like dengue, zika and chikungunya in Brazil in the last years has increased the concerns on protection against mosquito’s bites. However, the prohibitive prices of the commercially available repellents for the majority of the Brazilian population, has provoked a search for cheaper solutions, like the use of the homemade ethanolic extract of Indian clove (Syzygium aromaticum L.) as repellent, which has been reported as quite efficient by the local press. In order to verify this, we performed here, the quantification of the main components of this extract through high-performance thin-layer chromatography (HPTLC)-densitometry and evaluated its efficiency as repellent, as well as the acetylcholinesterase (AChE) inhibition capacity. Our results have proved HPTLC-densitometry as an efficient and appropriate method for this quantification and confirmed the repellency activity as well as its capacity of AChE inhibition.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/22816/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALFarmanguinhos (PREPRINT) - Quantification hrought TLC-Densitometric.....pdfFarmanguinhos (PREPRINT) - Quantification hrought TLC-Densitometric.....pdfapplication/pdf1374787https://www.arca.fiocruz.br/bitstream/icict/22816/2/Farmanguinhos%20%28PREPRINT%29%20-%20Quantification%20hrought%20TLC-Densitometric.....pdfd6c49b3797d254d184d0c0b4d15758acMD52TEXTFarmanguinhos (PREPRINT) - Quantification hrought TLC-Densitometric.....pdf.txtFarmanguinhos (PREPRINT) - Quantification hrought 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dc.title.pt_BR.fl_str_mv Quantification through TLC-Densitometric analysis, repellency and anticholinesterase activity of the homemade extract of Indian cloves
title Quantification through TLC-Densitometric analysis, repellency and anticholinesterase activity of the homemade extract of Indian cloves
spellingShingle Quantification through TLC-Densitometric analysis, repellency and anticholinesterase activity of the homemade extract of Indian cloves
Affonso, Raphael
Syzygium Aromaticum L.
Repelente de Insetos
Eugenol
Anti-Colinesterase
Aedes Aegypti
Syzygium Aromaticum L.
Insect Repellent
Eugenol
Anticholinesterase
Aedes Aegypti
title_short Quantification through TLC-Densitometric analysis, repellency and anticholinesterase activity of the homemade extract of Indian cloves
title_full Quantification through TLC-Densitometric analysis, repellency and anticholinesterase activity of the homemade extract of Indian cloves
title_fullStr Quantification through TLC-Densitometric analysis, repellency and anticholinesterase activity of the homemade extract of Indian cloves
title_full_unstemmed Quantification through TLC-Densitometric analysis, repellency and anticholinesterase activity of the homemade extract of Indian cloves
title_sort Quantification through TLC-Densitometric analysis, repellency and anticholinesterase activity of the homemade extract of Indian cloves
author Affonso, Raphael
author_facet Affonso, Raphael
Lima, Josélia
Lessa, Bruno
Caetano, João
Obara, Marcos
Nóbrega, Andrea
Nepominova, Eugenie
Musilek, Kamil
Kuca, Kamil
Slana, Gláucia Barbosa Candido Alves
França, Tanos
author_role author
author2 Lima, Josélia
Lessa, Bruno
Caetano, João
Obara, Marcos
Nóbrega, Andrea
Nepominova, Eugenie
Musilek, Kamil
Kuca, Kamil
Slana, Gláucia Barbosa Candido Alves
França, Tanos
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Affonso, Raphael
Lima, Josélia
Lessa, Bruno
Caetano, João
Obara, Marcos
Nóbrega, Andrea
Nepominova, Eugenie
Musilek, Kamil
Kuca, Kamil
Slana, Gláucia Barbosa Candido Alves
França, Tanos
dc.subject.other.pt_BR.fl_str_mv Syzygium Aromaticum L.
Repelente de Insetos
Eugenol
Anti-Colinesterase
Aedes Aegypti
topic Syzygium Aromaticum L.
Repelente de Insetos
Eugenol
Anti-Colinesterase
Aedes Aegypti
Syzygium Aromaticum L.
Insect Repellent
Eugenol
Anticholinesterase
Aedes Aegypti
dc.subject.en.pt_BR.fl_str_mv Syzygium Aromaticum L.
Insect Repellent
Eugenol
Anticholinesterase
Aedes Aegypti
description Instituto Militar de Engenharia. Modelagem Aplicada à Defesa Química e Biológica. Rio de Janeiro, RJ, Brasil.
publishDate 2017
dc.date.accessioned.fl_str_mv 2017-10-10T14:37:23Z
dc.date.available.fl_str_mv 2017-10-10T14:37:23Z
dc.date.issued.fl_str_mv 2017
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv AFFONSO, Raphael. Quantification through TLC-Densitometric analysis, repellency and anticholinesterase activity of the homemade extract of Indian cloves. Biomed Chromatogr, Sep 2017.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/22816
dc.identifier.doi.none.fl_str_mv 10.1002/bmc.4096
identifier_str_mv AFFONSO, Raphael. Quantification through TLC-Densitometric analysis, repellency and anticholinesterase activity of the homemade extract of Indian cloves. Biomed Chromatogr, Sep 2017.
10.1002/bmc.4096
url https://www.arca.fiocruz.br/handle/icict/22816
dc.language.iso.fl_str_mv por
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