Unveiling the Impact of the Omicron Variant: Insights from Genomic Surveillance in Mato Grosso do Sul, Midwest Brazil
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2023 |
| Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/60054 |
Resumo: | Estado do Mato Grosso do Sul. Secretaria de Saúde. Campo Grande, MS, Brazil/Universidade Federal de Mato Grosso do Sul. Campo Grande, MS, Brazil. |
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Maziero, Lívia de Mello AlmeidaGiovanetti, MartaFonseca, VagnerZardin, Marina Castilhos Souza UmakiLichs, Gislene Garcia de CastroRomera, Grazielli Rocha de RezendeTsuha, Daniel HenriqueFrias, Danila Fernanda RodriguesEscandolhero, Valdir CastanhoDemarchi, Luiz HenriqueCastilho, Larissa DominguesBarbosa, Karine FerreiraTebet, Danielle Galindo MartinsXavier, JoilsonFritsch, HeggerLima, MauricioOliveira, Carla deSantos, Elaine VieiraKashima, SimoneSaid, Rodrigo Fabiano do CarmoRosewell, AlexanderCroda, JulioAlcantara, Luiz Carlos JuniorGonçalves, Crhistinne Cavalheiro Maymone2023-08-11T19:40:21Z2023-08-11T19:40:21Z2023MAZIERO, Lívia de Mello Almeida et al. Unveiling the Impact of the Omicron Variant: Insights from Genomic Surveillance in Mato Grosso do Sul, Midwest Brazil. Viruses, v. 15, n. 7, 2023. doi.org/10.3390/v15071604.1999-4915https://www.arca.fiocruz.br/handle/icict/60054engMDPIUnveiling the Impact of the Omicron Variant: Insights from Genomic Surveillance in Mato Grosso do Sul, Midwest Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleEstado do Mato Grosso do Sul. Secretaria de Saúde. Campo Grande, MS, Brazil/Universidade Federal de Mato Grosso do Sul. Campo Grande, MS, Brazil.Fundação Oswaldo Cruz. Instituto Rene Rachou. Belo Horizonte, MG, Brazil/Sciences and Technologies for Sustainable Development and One Health. University of Campus Bio-Medico of Rome. Rome, Italy.Organização Pan-Americana da Saúde/Organização Mundial da Saúde. Coordenação de Vigilância, Preparação e Resposta à Emergências e Desastres. Brasília, DF, Brazil.Estado do Mato Grosso do Sul. Secretaria de Saúde. Laboratório Central de Saúde Pública. Campo Grande, MS, Brazil.Estado do Mato Grosso do Sul. Secretaria de Saúde. Laboratório Central de Saúde Pública. Campo Grande, MS, Brazil.Estado do Mato Grosso do Sul. Secretaria de Saúde. Campo Grande, MS, Brazil.Estado do Mato Grosso do Sul. Secretaria de Saúde. Campo Grande, MS, Brazil.Estado do Mato Grosso do Sul. Secretaria de Saúde. Campo Grande, MS, Brazil.Estado do Mato Grosso do Sul. Secretaria de Saúde. Campo Grande, MS, Brazil.Estado do Mato Grosso do Sul. Secretaria de Saúde. Laboratório Central de Saúde Pública. Campo Grande, MS, Brazil.Estado do Mato Grosso do Sul. Secretaria de Saúde. Campo Grande, MS, Brazil/Universidade Federal de Mato Grosso do Sul. Campo Grande, MS, Brazil.Estado do Mato Grosso do Sul. Secretaria de Saúde. Campo Grande, MS, Brazil/Universidade Federal de Mato Grosso do Sul. Campo Grande, MS, Brazil.Estado do Mato Grosso do Sul. Secretaria de Saúde. Campo Grande, MS, Brazil/Universidade Federal de Mato Grosso do Sul. Campo Grande, MS, Brazil.Fundação Oswaldo Cruz. Instituto Rene Rachou. Belo Horizonte, MG, Brazil.Fundação Oswaldo Cruz. Instituto Rene Rachou. Belo Horizonte, MG, Brazil.Fundação Oswaldo Cruz. Instituto Rene Rachou. Belo Horizonte, MG, Brazil.Fundação Oswaldo Cruz. lnstituto Oswaldo Cruz. Rio de Janeiro, RJ, Brazil.Fundação Hemocentro de Ribeirão Preto. Ribeirão Preto, SP, Brazil.Fundação Hemocentro de Ribeirão Preto. Ribeirão Preto, SP, Brazil.Organização Pan-Americana da Saúde/Organização Mundial da Saúde. Brasilia, DF, Brazil.Organização Pan-Americana da Saúde/Organização Mundial da Saúde. Brasilia, DF, Brazil.Universidade Federal de Mato Grosso do Sul. Campo Grande, MS, Brazil.Fundação Oswaldo Cruz. Instituto Rene Rachou. Belo Horizonte, MG, Brazil.Estado do Mato Grosso do Sul. Secretaria de Saúde. Campo Grande, MS, Brazil/Universidade Federal de Mato Grosso do Sul. Campo Grande, MS, Brazil.Genomic surveillance has emerged as a crucial tool in monitoring and understanding the dynamics of viral variants during the COVID-19 pandemic. In the Midwest region of Brazil, Mato Grosso do Sul has faced a significant burden from the SARS-CoV-2 epidemic, with a total of 613,000 confirmed cases as of June 2023. In collaboration with the Central Public Health Laboratory in the capital city of Campo Grande, we conducted a portable whole-genome sequencing and phylodynamic analysis to investigate the circulation of the Omicron variant in the region. The study aimed to uncover the genomic landscape and provide valuable insights into the prevalence and transmission patterns of this highly transmissible variant. Our findings revealed an increase in the number of cases within the region during 2022, followed by a gradual decline as a result of the successful impact of the vaccination program together with the capacity of this unpredictable and very transmissible variant to quickly affect the proportion of susceptible population. Genomic data indicated multiple introduction events, suggesting that human mobility played a differential role in the variant's dispersion dynamics throughout the state. These findings emphasize the significance of implementing public health interventions to mitigate further spread and highlight the powerful role of genomic monitoring in promptly tracking and uncovering the circulation of viral strains. Together those results underscore the importance of proactive surveillance, rapid genomic sequencing, and data sharing to facilitate timely public health responses.Mato Grosso do SulOmicron variantSARS-CoV-2genomic monitoringinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/60054/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALUnveiling the Impact of the Omicron Variant_ Insights from Genomic Surveillance in Mato Grosso do Sul, Midwest Brazil.pdfUnveiling the Impact of the Omicron Variant_ Insights from Genomic Surveillance in Mato Grosso do Sul, Midwest Brazil.pdfapplication/pdf1819743https://www.arca.fiocruz.br/bitstream/icict/60054/2/Unveiling%20the%20Impact%20of%20the%20Omicron%20Variant_%20Insights%20from%20Genomic%20Surveillance%20in%20Mato%20Grosso%20do%20Sul%2c%20Midwest%20Brazil.pdfaa0ecd0256f30b4a1165655fb9ef39bfMD52icict/600542023-08-11 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| dc.title.en_US.fl_str_mv |
Unveiling the Impact of the Omicron Variant: Insights from Genomic Surveillance in Mato Grosso do Sul, Midwest Brazil |
| title |
Unveiling the Impact of the Omicron Variant: Insights from Genomic Surveillance in Mato Grosso do Sul, Midwest Brazil |
| spellingShingle |
Unveiling the Impact of the Omicron Variant: Insights from Genomic Surveillance in Mato Grosso do Sul, Midwest Brazil Maziero, Lívia de Mello Almeida Mato Grosso do Sul Omicron variant SARS-CoV-2 genomic monitoring |
| title_short |
Unveiling the Impact of the Omicron Variant: Insights from Genomic Surveillance in Mato Grosso do Sul, Midwest Brazil |
| title_full |
Unveiling the Impact of the Omicron Variant: Insights from Genomic Surveillance in Mato Grosso do Sul, Midwest Brazil |
| title_fullStr |
Unveiling the Impact of the Omicron Variant: Insights from Genomic Surveillance in Mato Grosso do Sul, Midwest Brazil |
| title_full_unstemmed |
Unveiling the Impact of the Omicron Variant: Insights from Genomic Surveillance in Mato Grosso do Sul, Midwest Brazil |
| title_sort |
Unveiling the Impact of the Omicron Variant: Insights from Genomic Surveillance in Mato Grosso do Sul, Midwest Brazil |
| author |
Maziero, Lívia de Mello Almeida |
| author_facet |
Maziero, Lívia de Mello Almeida Giovanetti, Marta Fonseca, Vagner Zardin, Marina Castilhos Souza Umaki Lichs, Gislene Garcia de Castro Romera, Grazielli Rocha de Rezende Tsuha, Daniel Henrique Frias, Danila Fernanda Rodrigues Escandolhero, Valdir Castanho Demarchi, Luiz Henrique Castilho, Larissa Domingues Barbosa, Karine Ferreira Tebet, Danielle Galindo Martins Xavier, Joilson Fritsch, Hegger Lima, Mauricio Oliveira, Carla de Santos, Elaine Vieira Kashima, Simone Said, Rodrigo Fabiano do Carmo Rosewell, Alexander Croda, Julio Alcantara, Luiz Carlos Junior Gonçalves, Crhistinne Cavalheiro Maymone |
| author_role |
author |
| author2 |
Giovanetti, Marta Fonseca, Vagner Zardin, Marina Castilhos Souza Umaki Lichs, Gislene Garcia de Castro Romera, Grazielli Rocha de Rezende Tsuha, Daniel Henrique Frias, Danila Fernanda Rodrigues Escandolhero, Valdir Castanho Demarchi, Luiz Henrique Castilho, Larissa Domingues Barbosa, Karine Ferreira Tebet, Danielle Galindo Martins Xavier, Joilson Fritsch, Hegger Lima, Mauricio Oliveira, Carla de Santos, Elaine Vieira Kashima, Simone Said, Rodrigo Fabiano do Carmo Rosewell, Alexander Croda, Julio Alcantara, Luiz Carlos Junior Gonçalves, Crhistinne Cavalheiro Maymone |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Maziero, Lívia de Mello Almeida Giovanetti, Marta Fonseca, Vagner Zardin, Marina Castilhos Souza Umaki Lichs, Gislene Garcia de Castro Romera, Grazielli Rocha de Rezende Tsuha, Daniel Henrique Frias, Danila Fernanda Rodrigues Escandolhero, Valdir Castanho Demarchi, Luiz Henrique Castilho, Larissa Domingues Barbosa, Karine Ferreira Tebet, Danielle Galindo Martins Xavier, Joilson Fritsch, Hegger Lima, Mauricio Oliveira, Carla de Santos, Elaine Vieira Kashima, Simone Said, Rodrigo Fabiano do Carmo Rosewell, Alexander Croda, Julio Alcantara, Luiz Carlos Junior Gonçalves, Crhistinne Cavalheiro Maymone |
| dc.subject.en.en_US.fl_str_mv |
Mato Grosso do Sul Omicron variant SARS-CoV-2 genomic monitoring |
| topic |
Mato Grosso do Sul Omicron variant SARS-CoV-2 genomic monitoring |
| description |
Estado do Mato Grosso do Sul. Secretaria de Saúde. Campo Grande, MS, Brazil/Universidade Federal de Mato Grosso do Sul. Campo Grande, MS, Brazil. |
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2023 |
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2023-08-11T19:40:21Z |
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2023-08-11T19:40:21Z |
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2023 |
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MAZIERO, Lívia de Mello Almeida et al. Unveiling the Impact of the Omicron Variant: Insights from Genomic Surveillance in Mato Grosso do Sul, Midwest Brazil. Viruses, v. 15, n. 7, 2023. doi.org/10.3390/v15071604. |
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1999-4915 |
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MAZIERO, Lívia de Mello Almeida et al. Unveiling the Impact of the Omicron Variant: Insights from Genomic Surveillance in Mato Grosso do Sul, Midwest Brazil. Viruses, v. 15, n. 7, 2023. doi.org/10.3390/v15071604. 1999-4915 |
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