HAV infection in Brazilian men who have sex with men: The importance of surveillance to avoid outbreaks

Detalhes bibliográficos
Autor(a) principal: Castro, Lisie Souza
Data de Publicação: 2021
Outros Autores: Rezende, Grazielli Rocha de, Fernandes, Fernanda Rodas Pires, Bandeira, Larissa Melo, Cesar, Gabriela Alves, Lago, Barbara Vieira do, Gouvêa, Michele Soares Gomes, Motta-Castro, Ana R. C.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/51036
Resumo: Universidade Federal de Mato Grosso do Sul. Campo Grande, MS, Brasil / Universidade Federal de Mato Grosso. Rondonópolis, MT Brasil.
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spelling Castro, Lisie SouzaRezende, Grazielli Rocha deFernandes, Fernanda Rodas PiresBandeira, Larissa MeloCesar, Gabriela AlvesLago, Barbara Vieira doGouvêa, Michele Soares GomesMotta-Castro, Ana R. C.2022-02-05T20:37:00Z2022-02-05T20:37:00Z2021CASTRO, Lisie Souza et al. HAV infection in Brazilian men who have sex with men: The importance of surveillance to avoid outbreaks. Plos One, v. 16, n. 9, e0256818, p. 1 - 10, Sept. 2021.1932-6203https://www.arca.fiocruz.br/handle/icict/5103610.1371/journal.pone.0256818engPublic Library of ScienceInfecção HAVImportância para evitar surtosVigilânciaHomens que fazem sexo com homensAnticorpos Anti-Hepatite AHAV infectionMen who have sex with menSurveillanceImport to avoid outbreaksHepatitis A Virus AntibodiesHepatitis A Virus AntibodiesAnticorpos Anti-Hepatite AHAV infection in Brazilian men who have sex with men: The importance of surveillance to avoid outbreaksinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal de Mato Grosso do Sul. Campo Grande, MS, Brasil / Universidade Federal de Mato Grosso. Rondonópolis, MT Brasil.Universidade Federal de Mato Grosso do Sul. Campo Grande, MS, Brasil.Universidade Federal de Mato Grosso do Sul. Campo Grande, MS, Brasil / Ministério da Agricultura, Pecuária e Abastecimento. Laboratório Nacioanl Agropecuário. MInas Gerais, Brasil.Universidade Federal de Mato Grosso do Sul. Campo Grande, MS, Brasil.Universidade Federal de Mato Grosso do Sul. Campo Grande, MS, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil.Universidade Federal de São Paulo. Instituto de Medicina Tropical. São Paulo, SP, Brasil.Universidade Federal de Mato Grosso do Sul. Campo Grande, MS, Brasil / Fundação Oswaldo Cruz. Rio de Janeiro, Mato Grosso do Sul, Brasil.Background Hepatitis A is a fecal-oral infection caused by hepatitis A virus (HAV). Men who have sex with men (MSM) and transgender women (TW) have been reported as target groups for HAV infection. This study aimed to determine the seroprevalence, risk factors, and circulating strains associated with HAV infection among MSM and TW in Central Brazil. Methods A cross-sectional study was conducted from November 2011 to September 2013. Serum samples were collected from 425 individuals for anti-HAV antibody testing and HAV molecular characterization. Of them, 149 (35.1%) participants were self-identified as transgender women. Statistical analysis was performed to evaluate the risk factors of HAV seropositivity. Results The seroprevalence of HAV exposure was 69.7% (95% Confidence Interval: 65.3–74.0%). Serological evidence of HAV was significantly higher in participants who self-identified as transgender women (83.2%) than MSM (62.3%). Increasing age, non-white race, and lower monthly household income were independently associated with HAV exposure among MSM. Only lower monthly household income was independently associated with HAV exposure among TW. One anti-HAV IgM positive sample, from a transgender woman (0.2%), was detected and classified as subgenotype IA. Conclusions High HAV prevalence was observed, markedly among TW. Considering the risky sexual behaviors this population is exposed to, HAV vaccination and prevention programs targeting this population should be considered to prevent outbreaks and the burden of the disease.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/51036/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALBarbaraVieiradoLago_LisieCastro_etal_IOC_2021.pdfBarbaraVieiradoLago_LisieCastro_etal_IOC_2021.pdfapplication/pdf670148https://www.arca.fiocruz.br/bitstream/icict/51036/2/BarbaraVieiradoLago_LisieCastro_etal_IOC_2021.pdf7aaa7f987c51513b7b1c11c094bcb3c7MD52icict/510362022-06-24 12:59:55.42oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-06-24T15:59:55Repositório Institucional da FIOCRUZ (ARCA) - 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dc.title.pt_BR.fl_str_mv HAV infection in Brazilian men who have sex with men: The importance of surveillance to avoid outbreaks
title HAV infection in Brazilian men who have sex with men: The importance of surveillance to avoid outbreaks
spellingShingle HAV infection in Brazilian men who have sex with men: The importance of surveillance to avoid outbreaks
Castro, Lisie Souza
Infecção HAV
Importância para evitar surtos
Vigilância
Homens que fazem sexo com homens
Anticorpos Anti-Hepatite A
HAV infection
Men who have sex with men
Surveillance
Import to avoid outbreaks
Hepatitis A Virus Antibodies
Hepatitis A Virus Antibodies
Anticorpos Anti-Hepatite A
title_short HAV infection in Brazilian men who have sex with men: The importance of surveillance to avoid outbreaks
title_full HAV infection in Brazilian men who have sex with men: The importance of surveillance to avoid outbreaks
title_fullStr HAV infection in Brazilian men who have sex with men: The importance of surveillance to avoid outbreaks
title_full_unstemmed HAV infection in Brazilian men who have sex with men: The importance of surveillance to avoid outbreaks
title_sort HAV infection in Brazilian men who have sex with men: The importance of surveillance to avoid outbreaks
author Castro, Lisie Souza
author_facet Castro, Lisie Souza
Rezende, Grazielli Rocha de
Fernandes, Fernanda Rodas Pires
Bandeira, Larissa Melo
Cesar, Gabriela Alves
Lago, Barbara Vieira do
Gouvêa, Michele Soares Gomes
Motta-Castro, Ana R. C.
author_role author
author2 Rezende, Grazielli Rocha de
Fernandes, Fernanda Rodas Pires
Bandeira, Larissa Melo
Cesar, Gabriela Alves
Lago, Barbara Vieira do
Gouvêa, Michele Soares Gomes
Motta-Castro, Ana R. C.
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Castro, Lisie Souza
Rezende, Grazielli Rocha de
Fernandes, Fernanda Rodas Pires
Bandeira, Larissa Melo
Cesar, Gabriela Alves
Lago, Barbara Vieira do
Gouvêa, Michele Soares Gomes
Motta-Castro, Ana R. C.
dc.subject.other.pt_BR.fl_str_mv Infecção HAV
Importância para evitar surtos
Vigilância
Homens que fazem sexo com homens
Anticorpos Anti-Hepatite A
topic Infecção HAV
Importância para evitar surtos
Vigilância
Homens que fazem sexo com homens
Anticorpos Anti-Hepatite A
HAV infection
Men who have sex with men
Surveillance
Import to avoid outbreaks
Hepatitis A Virus Antibodies
Hepatitis A Virus Antibodies
Anticorpos Anti-Hepatite A
dc.subject.en.pt_BR.fl_str_mv HAV infection
Men who have sex with men
Surveillance
Import to avoid outbreaks
Hepatitis A Virus Antibodies
dc.subject.decs.pt_BR.fl_str_mv Hepatitis A Virus Antibodies
Anticorpos Anti-Hepatite A
description Universidade Federal de Mato Grosso do Sul. Campo Grande, MS, Brasil / Universidade Federal de Mato Grosso. Rondonópolis, MT Brasil.
publishDate 2021
dc.date.issued.fl_str_mv 2021
dc.date.accessioned.fl_str_mv 2022-02-05T20:37:00Z
dc.date.available.fl_str_mv 2022-02-05T20:37:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv CASTRO, Lisie Souza et al. HAV infection in Brazilian men who have sex with men: The importance of surveillance to avoid outbreaks. Plos One, v. 16, n. 9, e0256818, p. 1 - 10, Sept. 2021.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/51036
dc.identifier.issn.pt_BR.fl_str_mv 1932-6203
dc.identifier.doi.none.fl_str_mv 10.1371/journal.pone.0256818
identifier_str_mv CASTRO, Lisie Souza et al. HAV infection in Brazilian men who have sex with men: The importance of surveillance to avoid outbreaks. Plos One, v. 16, n. 9, e0256818, p. 1 - 10, Sept. 2021.
1932-6203
10.1371/journal.pone.0256818
url https://www.arca.fiocruz.br/handle/icict/51036
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Public Library of Science
publisher.none.fl_str_mv Public Library of Science
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
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instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/51036/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/51036/2/BarbaraVieiradoLago_LisieCastro_etal_IOC_2021.pdf
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