Association of the presence of residual anti-Toxoplasma gondii IgM in pregnant women and their respective family groups in Miracema, Northwest Rio de Janeiro, Brazil

Detalhes bibliográficos
Autor(a) principal: Ribeiro, Ana Claudia
Data de Publicação: 2008
Outros Autores: Mutis, Martha Suarez, Fernandes, Octavio
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
DOI: 10.1590/S0074-02762008000600013
Texto Completo: https://www.arca.fiocruz.br/handle/icict/29677
Resumo: Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Parasitologia. Rio de Janeiro, RJ. Brasil.
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spelling Ribeiro, Ana ClaudiaMutis, Martha SuarezFernandes, Octavio2018-10-23T11:39:51Z2018-10-23T11:39:51Z2008RIBEIRO, Ana Claudia; MUTIS, Martha Suarez; FERNANDES, Octavio. Association of the presence of residual anti-Toxoplasma gondii IgM in pregnant women and their respective family groups in Miracema, Northwest Rio de Janeiro, Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 103, n. 6, p. 591-594, Sept. 2008.0074-0276https://www.arca.fiocruz.br/handle/icict/2967710.1590/S0074-027620080006000131678-8060engFiocruz/IOCToxoplasmoseGrávidasAnticorpo avidezToxoplasmosisAvidity antibodyPregnant womenAssociation of the presence of residual anti-Toxoplasma gondii IgM in pregnant women and their respective family groups in Miracema, Northwest Rio de Janeiro, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Parasitologia. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Doenças Parasitárias. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Epidemiologia Molecular de Doenças Infecciosas. Rio de Janeiro, RJ. Brasil.The seroprevalence of toxoplasmosis in 832 pregnant women in Miracema, Rio de Janeiro, was determined and 75.1% (625) and 2.0% (17) were anti-Toxoplasma gondii IgG and IgM positive, respectively. Out of the 17 IgM positive pregnant women, only one had low avidity IgG corresponding to the acute phase of the infection. All the other women presented with high avidity IgG and also presented with residual IgM anti-T. gondii. Of this sample, 106 received home visits (this includes 11 family nuclei of pregnant women with residual IgM anti-T. gondii, 68 nuclei of only IgG positive pregnant women and 27 nuclei of pregnant women with no antibodies to anti-T. gondii), resulting in 267 individuals visited. Out of these 267 individuals, 21 were positive for IgG and IgM anti-T. gondii and were candidates for the IgG avidity test. All of them presented with high avidity IgG and residual IgM. Five of these IgM+ individuals were (5/238; 2.1%) relatives of IgM negative pregnant women. The other 16 (16/29; 55.2%) were relatives of IgM+ pregnant women who were positive for residual IgM anti-T. gondii. This association was statistically significant (p = 0.0000). The analysis presented herein raises questions regarding the presence of residual IgM anti-T. gondii such as genetic determinants or even constant antigenic stimuli for the same family cluster.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/29677/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALoctavio_fernandes_etal_IOC_2008.pdfoctavio_fernandes_etal_IOC_2008.pdfapplication/pdf270153https://www.arca.fiocruz.br/bitstream/icict/29677/2/octavio_fernandes_etal_IOC_2008.pdf1f9f91f3dd7ab1498b8a4fa38d598c13MD52TEXToctavio_fernandes_etal_IOC_2008.pdf.txtoctavio_fernandes_etal_IOC_2008.pdf.txtExtracted texttext/plain19063https://www.arca.fiocruz.br/bitstream/icict/29677/3/octavio_fernandes_etal_IOC_2008.pdf.txt2d10389cb6054f1f6e4e49fc6d102d8eMD53icict/296772023-10-25 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dc.title.pt_BR.fl_str_mv Association of the presence of residual anti-Toxoplasma gondii IgM in pregnant women and their respective family groups in Miracema, Northwest Rio de Janeiro, Brazil
title Association of the presence of residual anti-Toxoplasma gondii IgM in pregnant women and their respective family groups in Miracema, Northwest Rio de Janeiro, Brazil
spellingShingle Association of the presence of residual anti-Toxoplasma gondii IgM in pregnant women and their respective family groups in Miracema, Northwest Rio de Janeiro, Brazil
Ribeiro, Ana Claudia
Toxoplasmose
Grávidas
Anticorpo avidez
Toxoplasmosis
Avidity antibody
Pregnant women
title_short Association of the presence of residual anti-Toxoplasma gondii IgM in pregnant women and their respective family groups in Miracema, Northwest Rio de Janeiro, Brazil
title_full Association of the presence of residual anti-Toxoplasma gondii IgM in pregnant women and their respective family groups in Miracema, Northwest Rio de Janeiro, Brazil
title_fullStr Association of the presence of residual anti-Toxoplasma gondii IgM in pregnant women and their respective family groups in Miracema, Northwest Rio de Janeiro, Brazil
title_full_unstemmed Association of the presence of residual anti-Toxoplasma gondii IgM in pregnant women and their respective family groups in Miracema, Northwest Rio de Janeiro, Brazil
title_sort Association of the presence of residual anti-Toxoplasma gondii IgM in pregnant women and their respective family groups in Miracema, Northwest Rio de Janeiro, Brazil
author Ribeiro, Ana Claudia
author_facet Ribeiro, Ana Claudia
Mutis, Martha Suarez
Fernandes, Octavio
author_role author
author2 Mutis, Martha Suarez
Fernandes, Octavio
author2_role author
author
dc.contributor.author.fl_str_mv Ribeiro, Ana Claudia
Mutis, Martha Suarez
Fernandes, Octavio
dc.subject.other.pt_BR.fl_str_mv Toxoplasmose
Grávidas
Anticorpo avidez
topic Toxoplasmose
Grávidas
Anticorpo avidez
Toxoplasmosis
Avidity antibody
Pregnant women
dc.subject.en.pt_BR.fl_str_mv Toxoplasmosis
Avidity antibody
Pregnant women
description Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Parasitologia. Rio de Janeiro, RJ. Brasil.
publishDate 2008
dc.date.issued.fl_str_mv 2008
dc.date.accessioned.fl_str_mv 2018-10-23T11:39:51Z
dc.date.available.fl_str_mv 2018-10-23T11:39:51Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv RIBEIRO, Ana Claudia; MUTIS, Martha Suarez; FERNANDES, Octavio. Association of the presence of residual anti-Toxoplasma gondii IgM in pregnant women and their respective family groups in Miracema, Northwest Rio de Janeiro, Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 103, n. 6, p. 591-594, Sept. 2008.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/29677
dc.identifier.issn.pt_BR.fl_str_mv 0074-0276
dc.identifier.doi.none.fl_str_mv 10.1590/S0074-02762008000600013
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv RIBEIRO, Ana Claudia; MUTIS, Martha Suarez; FERNANDES, Octavio. Association of the presence of residual anti-Toxoplasma gondii IgM in pregnant women and their respective family groups in Miracema, Northwest Rio de Janeiro, Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 103, n. 6, p. 591-594, Sept. 2008.
0074-0276
10.1590/S0074-02762008000600013
1678-8060
url https://www.arca.fiocruz.br/handle/icict/29677
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fiocruz/IOC
publisher.none.fl_str_mv Fiocruz/IOC
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
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