Cross-Sectional Study of Hepatitis A Virus Infection in the Pantanal Population before Vaccine Implementation in Brazil: Usage of Non-Invasive Specimen Collection

Detalhes bibliográficos
Autor(a) principal: Tourinho, Renata Santos
Data de Publicação: 2015
Outros Autores: Almeida, Adilson José de, Villar, Livia Melo, Murat, Paula Guerra, Capelin, Gina Jonasson Mousquer, Castro, Ana Rita Coimbra Motta, Paula, Vanessa Salete de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/13117
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Desenvolvimento Tecnológico em Virologia. Rio de Janeiro, RJ, Brasil.
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spelling Tourinho, Renata SantosAlmeida, Adilson José deVillar, Livia MeloMurat, Paula GuerraCapelin, Gina Jonasson MousquerCastro, Ana Rita Coimbra MottaPaula, Vanessa Salete de2016-03-10T17:10:36Z2016-03-10T17:10:36Z2015TOURINHO, Renata Santos; et al. Cross-Sectional Study of Hepatitis A Virus Infection in the Pantanal Population before Vaccine Implementation in Brazil: Usage of Non-Invasive Specimen Collection. Int. J. Environ. Res. Public Health, v.12, n.7, p.7357-7369, June 2015.1660-4601https://www.arca.fiocruz.br/handle/icict/1311710.3390/ijerph120707357engMDPIVacinaHepatite AEpidemiologiaPantanal MatogrossenseEpidemiologyHepatitis AOral fluidVaccineCross-Sectional Study of Hepatitis A Virus Infection in the Pantanal Population before Vaccine Implementation in Brazil: Usage of Non-Invasive Specimen Collectioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Desenvolvimento Tecnológico em Virologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil.Universidade Federal de Mato Grosso do Sul. Departamento de Farmácia Bioquímica. Campo Grande, MS, Brasil.Universidade Federal de Mato Grosso do Sul. Departamento de Farmácia Bioquímica. Campo Grande, MS, Brasil.Universidade Federal de Mato Grosso do Sul. Departamento de Farmácia Bioquímica. Campo Grande, MS, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Desenvolvimento Tecnológico em Virologia. Rio de Janeiro, RJ, Brasil.Population-based prevalence studies are essential tools for screening of hepatitis A and provide important data on susceptible groups. However, surveillance in isolated communities is difficult because of the limited access to these areas and the need for blood sample collection. This study aimed to determine the anti-HAV prevalence using oral fluid samples to provide an alternative tool for epidemiological studies that might be useful for vaccination-related decisions. The study population was composed of 224 volunteers from South Pantanal, aged 3 to 86 years old. This study was performed using oral fluids, previously standardized for anti-HAV antibody detection, which were collected using a ChemBio device. Eluates were tested using modified commercial EIA to detect anti-HAV antibodies. The overall prevalence was 79.1%, corresponding to 178 reactive EIA tests out of 224 samples. The age stratified data revealed a prevalence of 47.8% between 0-10 years, 84% in 11-20 years and 91.9% in subjects older than 21 years. Results indicate that hepatitis A prevalence was higher in adolescents and adults, corroborating the literature reports. Thus, oral fluid samples could replace serum in HAV epidemiological studies in isolated communities as they are efficient at detecting anti-HAV antibodies.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/13117/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALrenata_tourinho_etal_IOC_2015.pdfrenata_tourinho_etal_IOC_2015.pdfapplication/pdf875801https://www.arca.fiocruz.br/bitstream/icict/13117/2/renata_tourinho_etal_IOC_2015.pdf300f632afb422351996500d188b06069MD52TEXTrenata_tourinho_etal_IOC_2015.pdf.txtrenata_tourinho_etal_IOC_2015.pdf.txtExtracted texttext/plain34694https://www.arca.fiocruz.br/bitstream/icict/13117/3/renata_tourinho_etal_IOC_2015.pdf.txtba2af3d2e97a480797d9903fcc4bc284MD53icict/131172018-04-02 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dc.title.pt_BR.fl_str_mv Cross-Sectional Study of Hepatitis A Virus Infection in the Pantanal Population before Vaccine Implementation in Brazil: Usage of Non-Invasive Specimen Collection
title Cross-Sectional Study of Hepatitis A Virus Infection in the Pantanal Population before Vaccine Implementation in Brazil: Usage of Non-Invasive Specimen Collection
spellingShingle Cross-Sectional Study of Hepatitis A Virus Infection in the Pantanal Population before Vaccine Implementation in Brazil: Usage of Non-Invasive Specimen Collection
Tourinho, Renata Santos
Vacina
Hepatite A
Epidemiologia
Pantanal Matogrossense
Epidemiology
Hepatitis A
Oral fluid
Vaccine
title_short Cross-Sectional Study of Hepatitis A Virus Infection in the Pantanal Population before Vaccine Implementation in Brazil: Usage of Non-Invasive Specimen Collection
title_full Cross-Sectional Study of Hepatitis A Virus Infection in the Pantanal Population before Vaccine Implementation in Brazil: Usage of Non-Invasive Specimen Collection
title_fullStr Cross-Sectional Study of Hepatitis A Virus Infection in the Pantanal Population before Vaccine Implementation in Brazil: Usage of Non-Invasive Specimen Collection
title_full_unstemmed Cross-Sectional Study of Hepatitis A Virus Infection in the Pantanal Population before Vaccine Implementation in Brazil: Usage of Non-Invasive Specimen Collection
title_sort Cross-Sectional Study of Hepatitis A Virus Infection in the Pantanal Population before Vaccine Implementation in Brazil: Usage of Non-Invasive Specimen Collection
author Tourinho, Renata Santos
author_facet Tourinho, Renata Santos
Almeida, Adilson José de
Villar, Livia Melo
Murat, Paula Guerra
Capelin, Gina Jonasson Mousquer
Castro, Ana Rita Coimbra Motta
Paula, Vanessa Salete de
author_role author
author2 Almeida, Adilson José de
Villar, Livia Melo
Murat, Paula Guerra
Capelin, Gina Jonasson Mousquer
Castro, Ana Rita Coimbra Motta
Paula, Vanessa Salete de
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Tourinho, Renata Santos
Almeida, Adilson José de
Villar, Livia Melo
Murat, Paula Guerra
Capelin, Gina Jonasson Mousquer
Castro, Ana Rita Coimbra Motta
Paula, Vanessa Salete de
dc.subject.other.pt_BR.fl_str_mv Vacina
Hepatite A
Epidemiologia
Pantanal Matogrossense
topic Vacina
Hepatite A
Epidemiologia
Pantanal Matogrossense
Epidemiology
Hepatitis A
Oral fluid
Vaccine
dc.subject.en.pt_BR.fl_str_mv Epidemiology
Hepatitis A
Oral fluid
Vaccine
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Desenvolvimento Tecnológico em Virologia. Rio de Janeiro, RJ, Brasil.
publishDate 2015
dc.date.issued.fl_str_mv 2015
dc.date.accessioned.fl_str_mv 2016-03-10T17:10:36Z
dc.date.available.fl_str_mv 2016-03-10T17:10:36Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv TOURINHO, Renata Santos; et al. Cross-Sectional Study of Hepatitis A Virus Infection in the Pantanal Population before Vaccine Implementation in Brazil: Usage of Non-Invasive Specimen Collection. Int. J. Environ. Res. Public Health, v.12, n.7, p.7357-7369, June 2015.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/13117
dc.identifier.issn.none.fl_str_mv 1660-4601
dc.identifier.doi.none.fl_str_mv 10.3390/ijerph120707357
identifier_str_mv TOURINHO, Renata Santos; et al. Cross-Sectional Study of Hepatitis A Virus Infection in the Pantanal Population before Vaccine Implementation in Brazil: Usage of Non-Invasive Specimen Collection. Int. J. Environ. Res. Public Health, v.12, n.7, p.7357-7369, June 2015.
1660-4601
10.3390/ijerph120707357
url https://www.arca.fiocruz.br/handle/icict/13117
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/13117/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/13117/2/renata_tourinho_etal_IOC_2015.pdf
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