Revisiting Trypanosoma rangeli Transmission Involving Susceptible and Non-Susceptible Hosts

Detalhes bibliográficos
Autor(a) principal: Ferreira, Luciana de Lima
Data de Publicação: 2015
Outros Autores: Pereira, Marcos Horácio, Guarneri, Alessandra Aparecida
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/13120
Resumo: Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Comportamento de Vetores e Interação com Patógenos. Belo Horizonte, MG, Brasil
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spelling Ferreira, Luciana de LimaPereira, Marcos HorácioGuarneri, Alessandra Aparecida2016-03-11T17:16:51Z2016-03-11T17:16:51Z2015FERREIRA, Luciana de Lima; PEREIRA, Marcos Horácio; GUARNERI, Alessandra Aparecida. Revisiting Trypanosoma rangeli Transmission Involving Susceptible and Non-Susceptible Hosts. PLoS ONE, vol. 10, n. 10. Art. e0140575, 2015.1932-6203https://www.arca.fiocruz.br/handle/icict/1312010.1371/journal.pone.0140575engPublic Library of ScienceRevisiting Trypanosoma rangeli Transmission Involving Susceptible and Non-Susceptible Hostsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Comportamento de Vetores e Interação com Patógenos. Belo Horizonte, MG, BrasilUniversidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Parasitologia. Belo Horizonte, MG, BrasilFundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Comportamento de Vetores e Interação com Patógenos. Belo Horizonte, MG, BrasilTrypanosoma rangeli infects several triatomine and mammal species in South America. Its transmission is known to occur when a healthy insect feeds on an infected mammal or when an infected insect bites a healthy mammal. In the present study we evaluated the classic way of T. rangeli transmission started by the bite of a single infected triatomine, as well as alternative ways of circulation of this parasite among invertebrate hosts. The number of metacyclic trypomastigotes eliminated from salivary glands during a blood meal was quantified for unfed and recently fed nymphs. The quantification showed that ~50,000 parasites can be liberated during a single blood meal. The transmission of T. rangeli from mice to R. prolixus was evaluated using infections started through the bite of a single infected nymph. The mice that served as the blood source for single infected nymphs showed a high percentage of infection and efficiently transmitted the infection to new insects. Parasites were recovered by xenodiagnosis in insects fed on mice with infections that lasted approximately four months. Hemolymphagy and co-feeding were tested to evaluate insect-insect T. rangeli transmission. T. rangeli was not transmitted during hemolymphagy. However, insects that had co-fed on mice with infected conspecifics exhibited infection rates of approximately 80%. Surprisingly, 16% of the recipient nymphs became infected when pigeons were used as hosts. Our results show that T. rangeli is efficiently transmitted between the evaluated hosts. Not only are the insect-mouse-insect transmission rates high, but parasites can also be transmitted between insects while co-feeding on a living host. We show for the first time that birds can be part of the T. rangeli transmission cycle as we proved that insect-insect transmission is feasible during a co-feeding on these hosts.NymphsInsectsParasitic diseasesHost-pathogen interactionsParasitic intestinal diseasesBloodSalivary glandsPigeonsinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/13120/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALRevisiting Trypanosoma rangeli Transmission Involving Susceptible and Non-Susceptible Hosts.pdfRevisiting Trypanosoma rangeli Transmission Involving Susceptible and Non-Susceptible Hosts.pdfapplication/pdf438567https://www.arca.fiocruz.br/bitstream/icict/13120/2/Revisiting%20Trypanosoma%20rangeli%20Transmission%20Involving%20Susceptible%20and%20Non-Susceptible%20Hosts.pdfad700ae3da5ea0d4deba26067403c799MD52TEXTRevisiting Trypanosoma rangeli Transmission Involving Susceptible and Non-Susceptible Hosts.pdf.txtRevisiting Trypanosoma rangeli Transmission Involving Susceptible and Non-Susceptible Hosts.pdf.txtExtracted texttext/plain49772https://www.arca.fiocruz.br/bitstream/icict/13120/3/Revisiting%20Trypanosoma%20rangeli%20Transmission%20Involving%20Susceptible%20and%20Non-Susceptible%20Hosts.pdf.txt971b91675f297e0aad63434980f8dbe4MD53icict/131202019-06-19 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dc.title.pt_BR.fl_str_mv Revisiting Trypanosoma rangeli Transmission Involving Susceptible and Non-Susceptible Hosts
title Revisiting Trypanosoma rangeli Transmission Involving Susceptible and Non-Susceptible Hosts
spellingShingle Revisiting Trypanosoma rangeli Transmission Involving Susceptible and Non-Susceptible Hosts
Ferreira, Luciana de Lima
Nymphs
Insects
Parasitic diseases
Host-pathogen interactions
Parasitic intestinal diseases
Blood
Salivary glands
Pigeons
title_short Revisiting Trypanosoma rangeli Transmission Involving Susceptible and Non-Susceptible Hosts
title_full Revisiting Trypanosoma rangeli Transmission Involving Susceptible and Non-Susceptible Hosts
title_fullStr Revisiting Trypanosoma rangeli Transmission Involving Susceptible and Non-Susceptible Hosts
title_full_unstemmed Revisiting Trypanosoma rangeli Transmission Involving Susceptible and Non-Susceptible Hosts
title_sort Revisiting Trypanosoma rangeli Transmission Involving Susceptible and Non-Susceptible Hosts
author Ferreira, Luciana de Lima
author_facet Ferreira, Luciana de Lima
Pereira, Marcos Horácio
Guarneri, Alessandra Aparecida
author_role author
author2 Pereira, Marcos Horácio
Guarneri, Alessandra Aparecida
author2_role author
author
dc.contributor.author.fl_str_mv Ferreira, Luciana de Lima
Pereira, Marcos Horácio
Guarneri, Alessandra Aparecida
dc.subject.en.pt_BR.fl_str_mv Nymphs
Insects
Parasitic diseases
Host-pathogen interactions
Parasitic intestinal diseases
Blood
Salivary glands
Pigeons
topic Nymphs
Insects
Parasitic diseases
Host-pathogen interactions
Parasitic intestinal diseases
Blood
Salivary glands
Pigeons
description Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Comportamento de Vetores e Interação com Patógenos. Belo Horizonte, MG, Brasil
publishDate 2015
dc.date.issued.fl_str_mv 2015
dc.date.accessioned.fl_str_mv 2016-03-11T17:16:51Z
dc.date.available.fl_str_mv 2016-03-11T17:16:51Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv FERREIRA, Luciana de Lima; PEREIRA, Marcos Horácio; GUARNERI, Alessandra Aparecida. Revisiting Trypanosoma rangeli Transmission Involving Susceptible and Non-Susceptible Hosts. PLoS ONE, vol. 10, n. 10. Art. e0140575, 2015.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/13120
dc.identifier.issn.none.fl_str_mv 1932-6203
dc.identifier.doi.none.fl_str_mv 10.1371/journal.pone.0140575
identifier_str_mv FERREIRA, Luciana de Lima; PEREIRA, Marcos Horácio; GUARNERI, Alessandra Aparecida. Revisiting Trypanosoma rangeli Transmission Involving Susceptible and Non-Susceptible Hosts. PLoS ONE, vol. 10, n. 10. Art. e0140575, 2015.
1932-6203
10.1371/journal.pone.0140575
url https://www.arca.fiocruz.br/handle/icict/13120
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Public Library of Science
publisher.none.fl_str_mv Public Library of Science
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/13120/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/13120/2/Revisiting%20Trypanosoma%20rangeli%20Transmission%20Involving%20Susceptible%20and%20Non-Susceptible%20Hosts.pdf
https://www.arca.fiocruz.br/bitstream/icict/13120/3/Revisiting%20Trypanosoma%20rangeli%20Transmission%20Involving%20Susceptible%20and%20Non-Susceptible%20Hosts.pdf.txt
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