Essential oils from two Lantana species with antimycobacterial activity

Detalhes bibliográficos
Autor(a) principal: Julião, Lisieux de Santana
Data de Publicação: 2009
Outros Autores: Bizzo, Humberto R., Souza, Andressa M., Lourenço, Maria Cristina S., Silva, Pedro Eduardo A., Tavares, Eliana S., Rastrelli, Luca, Leitão, Suzana Guimarães
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/39086
Resumo: Universidade Federal do Rio de Janeiro. Centro de Ciências da Saúde. Programa de Biotecnologia Vegetal. Rio de Janeiro, RJ, Brasil.
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spelling Julião, Lisieux de SantanaBizzo, Humberto R.Souza, Andressa M.Lourenço, Maria Cristina S.Silva, Pedro Eduardo A.Tavares, Eliana S.Rastrelli, LucaLeitão, Suzana Guimarães2020-01-09T14:06:23Z2020-01-09T14:06:23Z2009JULIÃO, Lisieux de Santana et al. Essential oils from two Lantana species with antimycobacterial activity. Natural Product Communications, v. 4, n. 12, p. 1733-1736, 2009.1934-578Xhttps://www.arca.fiocruz.br/handle/icict/3908610.1177/1934578X09004012241555-9475porSAGE PublicationsEssential oils from two Lantana species with antimycobacterial activityinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal do Rio de Janeiro. Centro de Ciências da Saúde. Programa de Biotecnologia Vegetal. Rio de Janeiro, RJ, Brasil.Embrapa Agroindústria de Alimentos. Rio de Janeiro, RJ, Brasil.Embrapa Agroindústria de Alimentos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Bacteriologia e Bioensaios em Micobactérias. Plataforma de Bioensaios II. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio Grande. Laboratório de Micobactérias. Rio Grande, RS, Brasil.Universidade Federal do Rio de Janeiro. Centro de Ciências da Saúde. Programa de Biotecnologia Vegetal. Rio de Janeiro, RJ, Brasil.Università degli Studi di Salerno. Dipartimento di Scienze Farmaceutiche. Fisciano, Italy.Universidade Federal do Rio de Janeiro. Faculdade de Farmácia. Departamento de Produtos Naturais e Alimentos. Rio de Janeiro, RJ, Brasil.Lantana trifolia L. and L. fucata Lindl. are two Brazilian species used in folk medicine for the treatment of respiratory disorders. The composition of the essential oils from the leaves was investigated, as well as their in vitro activity against Mycobacterium tuberculosis. L. trifolia yielded an oil (0.2%) rich in sesquiterpenes. The major substances found were germacrene D (45.1%), (E)-caryophyllene (12.8%), bicyclogermacrene (12.7%) and α-humulene (4.4%). Sesquiterpenes were also the main components of the oil of L. fucata (0.3% yield), the principal ones being β-elemene (27.1%), germacrene D (11.6%), (E)-caryophyllene (7.7%), valencene (5.7%) and germacrene A (4.6%). Both oils exhibited in vitro antimycobacterial activity by the MABA assay with MICs of 80 μg/mL for L. trifolia and 100 μg/mL for L. fucata.Lantana trifolia L.Lantana fucata Lindl.Essential oilMABAMycobacterium tuberculosisTuberculosisVerbenaceaeinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/39086/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALve_Julião_Lisieux_etal_INI_2019.pdfve_Julião_Lisieux_etal_INI_2019.pdfapplication/pdf213273https://www.arca.fiocruz.br/bitstream/icict/39086/2/ve_Juli%c3%a3o_Lisieux_etal_INI_2019.pdfda403e9422770cd1e9125fa0324ac856MD52TEXTve_Julião_Lisieux_etal_INI_2019.pdf.txtve_Julião_Lisieux_etal_INI_2019.pdf.txtExtracted texttext/plain18968https://www.arca.fiocruz.br/bitstream/icict/39086/3/ve_Juli%c3%a3o_Lisieux_etal_INI_2019.pdf.txt121aa3d1fd08cad1cedb0ec57a9b2de7MD53icict/390862020-01-10 02:02:27.085oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352020-01-10T05:02:27Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Essential oils from two Lantana species with antimycobacterial activity
title Essential oils from two Lantana species with antimycobacterial activity
spellingShingle Essential oils from two Lantana species with antimycobacterial activity
Julião, Lisieux de Santana
Lantana trifolia L.
Lantana fucata Lindl.
Essential oil
MABA
Mycobacterium tuberculosis
Tuberculosis
Verbenaceae
title_short Essential oils from two Lantana species with antimycobacterial activity
title_full Essential oils from two Lantana species with antimycobacterial activity
title_fullStr Essential oils from two Lantana species with antimycobacterial activity
title_full_unstemmed Essential oils from two Lantana species with antimycobacterial activity
title_sort Essential oils from two Lantana species with antimycobacterial activity
author Julião, Lisieux de Santana
author_facet Julião, Lisieux de Santana
Bizzo, Humberto R.
Souza, Andressa M.
Lourenço, Maria Cristina S.
Silva, Pedro Eduardo A.
Tavares, Eliana S.
Rastrelli, Luca
Leitão, Suzana Guimarães
author_role author
author2 Bizzo, Humberto R.
Souza, Andressa M.
Lourenço, Maria Cristina S.
Silva, Pedro Eduardo A.
Tavares, Eliana S.
Rastrelli, Luca
Leitão, Suzana Guimarães
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Julião, Lisieux de Santana
Bizzo, Humberto R.
Souza, Andressa M.
Lourenço, Maria Cristina S.
Silva, Pedro Eduardo A.
Tavares, Eliana S.
Rastrelli, Luca
Leitão, Suzana Guimarães
dc.subject.en.pt_BR.fl_str_mv Lantana trifolia L.
Lantana fucata Lindl.
Essential oil
MABA
Mycobacterium tuberculosis
Tuberculosis
Verbenaceae
topic Lantana trifolia L.
Lantana fucata Lindl.
Essential oil
MABA
Mycobacterium tuberculosis
Tuberculosis
Verbenaceae
description Universidade Federal do Rio de Janeiro. Centro de Ciências da Saúde. Programa de Biotecnologia Vegetal. Rio de Janeiro, RJ, Brasil.
publishDate 2009
dc.date.issued.fl_str_mv 2009
dc.date.accessioned.fl_str_mv 2020-01-09T14:06:23Z
dc.date.available.fl_str_mv 2020-01-09T14:06:23Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv JULIÃO, Lisieux de Santana et al. Essential oils from two Lantana species with antimycobacterial activity. Natural Product Communications, v. 4, n. 12, p. 1733-1736, 2009.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/39086
dc.identifier.issn.pt_BR.fl_str_mv 1934-578X
dc.identifier.doi.none.fl_str_mv 10.1177/1934578X0900401224
dc.identifier.eissn.none.fl_str_mv 1555-9475
identifier_str_mv JULIÃO, Lisieux de Santana et al. Essential oils from two Lantana species with antimycobacterial activity. Natural Product Communications, v. 4, n. 12, p. 1733-1736, 2009.
1934-578X
10.1177/1934578X0900401224
1555-9475
url https://www.arca.fiocruz.br/handle/icict/39086
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dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv SAGE Publications
publisher.none.fl_str_mv SAGE Publications
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
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