Radiographic aspects in individuals infected by human T-lymphotropic virus type 1 (HTLV-1) with joint pain

Detalhes bibliográficos
Autor(a) principal: Carvalho, João Marcos da Silva
Data de Publicação: 2022
Outros Autores: Campos, Eugênia Maria Teixeira de Araújo, Ferreira, José Luiz Nunes, Carvalho, Huliana Mourão, Carneiro Neto, José Abraão, Carneiro, Tássila de Oliveira, Carvalho, Edgar Marcelino
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/54817
Resumo: Fundação Maria Emília Pedreira Freire de Carvalho. Conselho Nacional de Pesquisa (CNPq). Ministério da Ciência, Tecnologia e Inovação. Fundação de Amparo à Pesquisa do Estado da Bahia (FAPESB).
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spelling Carvalho, João Marcos da SilvaCampos, Eugênia Maria Teixeira de AraújoFerreira, José Luiz NunesCarvalho, Huliana MourãoCarneiro Neto, José AbraãoCarneiro, Tássila de OliveiraCarvalho, Edgar Marcelino2022-09-20T14:16:14Z2022-09-20T14:16:14Z2022CARVALHO, João Marcos da Silva et al. Radiographic aspects in individuals infected by human T-lymphotropic virus type 1 (HTLV-1) with joint pain. Advances in Rheumatology, v. 62, n. 31, p. 1-7, 2022.2523-3106https://www.arca.fiocruz.br/handle/icict/5481710.1186/s42358-022-00259-yFundação Maria Emília Pedreira Freire de Carvalho. Conselho Nacional de Pesquisa (CNPq). Ministério da Ciência, Tecnologia e Inovação. Fundação de Amparo à Pesquisa do Estado da Bahia (FAPESB).Universidade Federal da Bahia. Programa de Pós-Graduação em Ciências da Saúde. Serviço de Imunologia do HUPES. Salvador, BA, Brasil / Universidade Federal da Bahia. Hospital Universitário Professor Edgard Santos. Divisão de Imunologia. Salvador, BA, Brasil.Universidade Federal da Bahia. Programa de Pós-Graduação em Ciências da Saúde. Serviço de Imunologia do HUPES. Salvador, BA, Brasil / Universidade Federal da Bahia. Hospital Universitário Professor Edgard Santos. Divisão de Imunologia. Salvador, BA, Brasil.Colégio Brasileiro de Radiologia E Diagnóstico por Imagem. Clínica de Diagnóstico por Imagem. Salvador, BA, Brasil.Universidade Federal da Bahia. Programa de Pós-Graduação em Ciências da Saúde. Serviço de Imunologia do HUPES. Salvador, BA, Brasil / Universidade Federal da Bahia. Hospital Universitário Professor Edgard Santos. Divisão de Imunologia. Salvador, BA, Brasil.Universidade Federal da Bahia. Programa de Pós-Graduação em Ciências da Saúde. Serviço de Imunologia do HUPES. Salvador, BA, Brasil / Universidade Federal da Bahia. Hospital Universitário Professor Edgard Santos. Divisão de Imunologia. Salvador, BA, Brasil.Escola Baiana de Medicina e Saúde Pública. Salvador, BA, Brasil.Universidade Federal da Bahia. Programa de Pós-Graduação em Ciências da Saúde. Serviço de Imunologia do HUPES. Salvador, BA, Brasil / Universidade Federal da Bahia. Hospital Universitário Professor Edgard Santos. Divisão de Imunologia. Salvador, BA, Brasil / Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Universidade Federal da Bahia. Faculdade de Medicina. Salvador, BA, Brasil.Background: Joint pain in the absence or with little synovitis is observed in a large percentage of HTLV-1 infected subjects. As the virus infect CD4+and CD8+positive, macrophages and B cells an exaggerated production of pro infammatory cytokines is detected in these patients. However, the possible association of HTLV-1 infection with auto immune diseases has not been documented defnitively and the clinical characteristics of HTLV-1 associated arthropa thy has not been defned. The objective this study is to describe clinic and radiographic features in HTLV-1-infected individuals with complaints of joint pain. Methods: Cross-sectional study enrolling HTLV-1-infected individuals with chronic joint pain, aged up to 75 years, both genders and seronegative controls with osteoarthritis. All participants underwent conventional radiography of the hips, knees and ankles. Results: Eighty-one HTLV-1 infected patients and 30 subjects with osteoarthritis participated in the study. Polyarticu lar and symmetrical arthritis prevailed in the HTLV-1 positive group (54%), while oligoarticular and asymmetrical (44%) were more common in controls (p<0.05). The frequency of enthesophytes (90%) in HTLV-1-infected patients was greater than in the control group (73%) (p<0.05). Radiographic features were similar in HTLV-1 carriers and in patients with probable or defnite HTLV-1 associated myelopathy. The presence of enthesophytes in the absence of joint space reduction or osteophytes was only observed in HTLV-1-infected individuals (p<0.001). Magnetic resonance imaging of the ankles of fve HTLV-1-infected patients and fve controls demonstrated a higher frequency of enthesitis, bursitis and osteitis in the HTLV-1 infected group. Conclusion: HTLV-1-associated arthropathy is clinically characterized by symmetrical polyarthralgia and the main radiological fnding is the presence of enthesophytes in the absence of osteophytes and joint space narrowing.engBMCHuman T-lymphotropic virus 1ArthralgiaHTLV-1Artropatia associada ao HTLV-1ArtralgiaAspectos radiográficosHTLV-1HTLV-1-associated arthropathyArthralgiaRadiographic aspectsAnticorpos Anti-HIVArtralgiaRadiographic aspects in individuals infected by human T-lymphotropic virus type 1 (HTLV-1) with joint paininfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/54817/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALCarvalho, João Marcos - Radiographic aspects in individuals infected....pdfCarvalho, João Marcos - 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dc.title.en_US.fl_str_mv Radiographic aspects in individuals infected by human T-lymphotropic virus type 1 (HTLV-1) with joint pain
title Radiographic aspects in individuals infected by human T-lymphotropic virus type 1 (HTLV-1) with joint pain
spellingShingle Radiographic aspects in individuals infected by human T-lymphotropic virus type 1 (HTLV-1) with joint pain
Carvalho, João Marcos da Silva
Human T-lymphotropic virus 1
Arthralgia
HTLV-1
Artropatia associada ao HTLV-1
Artralgia
Aspectos radiográficos
HTLV-1
HTLV-1-associated arthropathy
Arthralgia
Radiographic aspects
Anticorpos Anti-HIV
Artralgia
title_short Radiographic aspects in individuals infected by human T-lymphotropic virus type 1 (HTLV-1) with joint pain
title_full Radiographic aspects in individuals infected by human T-lymphotropic virus type 1 (HTLV-1) with joint pain
title_fullStr Radiographic aspects in individuals infected by human T-lymphotropic virus type 1 (HTLV-1) with joint pain
title_full_unstemmed Radiographic aspects in individuals infected by human T-lymphotropic virus type 1 (HTLV-1) with joint pain
title_sort Radiographic aspects in individuals infected by human T-lymphotropic virus type 1 (HTLV-1) with joint pain
author Carvalho, João Marcos da Silva
author_facet Carvalho, João Marcos da Silva
Campos, Eugênia Maria Teixeira de Araújo
Ferreira, José Luiz Nunes
Carvalho, Huliana Mourão
Carneiro Neto, José Abraão
Carneiro, Tássila de Oliveira
Carvalho, Edgar Marcelino
author_role author
author2 Campos, Eugênia Maria Teixeira de Araújo
Ferreira, José Luiz Nunes
Carvalho, Huliana Mourão
Carneiro Neto, José Abraão
Carneiro, Tássila de Oliveira
Carvalho, Edgar Marcelino
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Carvalho, João Marcos da Silva
Campos, Eugênia Maria Teixeira de Araújo
Ferreira, José Luiz Nunes
Carvalho, Huliana Mourão
Carneiro Neto, José Abraão
Carneiro, Tássila de Oliveira
Carvalho, Edgar Marcelino
dc.subject.mesh.en_US.fl_str_mv Human T-lymphotropic virus 1
Arthralgia
topic Human T-lymphotropic virus 1
Arthralgia
HTLV-1
Artropatia associada ao HTLV-1
Artralgia
Aspectos radiográficos
HTLV-1
HTLV-1-associated arthropathy
Arthralgia
Radiographic aspects
Anticorpos Anti-HIV
Artralgia
dc.subject.other.en_US.fl_str_mv HTLV-1
Artropatia associada ao HTLV-1
Artralgia
Aspectos radiográficos
dc.subject.en.en_US.fl_str_mv HTLV-1
HTLV-1-associated arthropathy
Arthralgia
Radiographic aspects
dc.subject.decs.en_US.fl_str_mv Anticorpos Anti-HIV
Artralgia
description Fundação Maria Emília Pedreira Freire de Carvalho. Conselho Nacional de Pesquisa (CNPq). Ministério da Ciência, Tecnologia e Inovação. Fundação de Amparo à Pesquisa do Estado da Bahia (FAPESB).
publishDate 2022
dc.date.accessioned.fl_str_mv 2022-09-20T14:16:14Z
dc.date.available.fl_str_mv 2022-09-20T14:16:14Z
dc.date.issued.fl_str_mv 2022
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv CARVALHO, João Marcos da Silva et al. Radiographic aspects in individuals infected by human T-lymphotropic virus type 1 (HTLV-1) with joint pain. Advances in Rheumatology, v. 62, n. 31, p. 1-7, 2022.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/54817
dc.identifier.issn.en_US.fl_str_mv 2523-3106
dc.identifier.doi.none.fl_str_mv 10.1186/s42358-022-00259-y
identifier_str_mv CARVALHO, João Marcos da Silva et al. Radiographic aspects in individuals infected by human T-lymphotropic virus type 1 (HTLV-1) with joint pain. Advances in Rheumatology, v. 62, n. 31, p. 1-7, 2022.
2523-3106
10.1186/s42358-022-00259-y
url https://www.arca.fiocruz.br/handle/icict/54817
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv BMC
publisher.none.fl_str_mv BMC
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instacron:FIOCRUZ
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collection Repositório Institucional da FIOCRUZ (ARCA)
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