Relapse in leprosy and drug resistance assessment in a tertiary hospital of the state of Espírito Santo, Brazil

Detalhes bibliográficos
Autor(a) principal: Chagas, Danielle Ferreira
Data de Publicação: 2021
Outros Autores: Diniz, Lucia Martins, Lucas, Elton Almeida, Moraes, Milton Ozório de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/51119
Resumo: Universidade Federal do Espirito Santo. Hospital Universitário Cassiano Antônio Morais. Serviço de Dermatologia. Vitória, ES, Brasil.
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spelling Chagas, Danielle FerreiraDiniz, Lucia MartinsLucas, Elton AlmeidaMoraes, Milton Ozório de2022-02-09T17:50:01Z2022-02-09T17:50:01Z2021CHAGAS, Danielle Ferreira et al. Relapse in leprosy and drug resistance assessment in a tertiary hospital of the state of Espírito Santo, Brazil. Revista da Sociedade Brasileira de Medicina Tropical, v. 54, e0375-2020, p. 1 - 4, 2021.1678-9849https://www.arca.fiocruz.br/handle/icict/5111910.1590/0037-8682-0375-2020engSociedade Brasileira de Medicina TropicalHanseníaseRecorrênciaEpidemiologiaResistência a drogaLeprosyRecurrenceEpidemiologyDrug resistanceRelapse in leprosy and drug resistance assessment in a tertiary hospital of the state of Espírito Santo, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal do Espirito Santo. Hospital Universitário Cassiano Antônio Morais. Serviço de Dermatologia. Vitória, ES, Brasil.Universidade Federal do Espirito Santo. Hospital Universitário Cassiano Antônio Morais. Serviço de Dermatologia. Vitória, ES, Brasil.Universidade Federal do Espirito Santo. Hospital Universitário Cassiano Antônio Morais. Serviço de Dermatologia. Vitória, ES, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Serviço de Hansenologia. Rio de Janeiro, RJ, Brasil.Leprosy recurrence is the reappearance of the disease after treatment with current schemes and discharged for cure and may have variable incubation periods. Methods: This is a descriptive observational study of leprosy recurrence in Espírito Santo diagnosed between January 2018 and January 2020. Results: One hundred and ninety-two cases were available, of which 30 were diagnosed with leprosy recurrence. Conclusions: In 25 cases, the incubation period was 5–15 years after the first treatment, favoring bacillary persistence. In the remaining 5 cases, the disease had recurred after 15 years, pointing to reinfection as none of them exhibited drug resistance.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/51119/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALMiltonMoraes_DanielleChagas_etal_IOC_2021.pdfMiltonMoraes_DanielleChagas_etal_IOC_2021.pdfapplication/pdf964896https://www.arca.fiocruz.br/bitstream/icict/51119/2/MiltonMoraes_DanielleChagas_etal_IOC_2021.pdfa780a53635fbf5aa53751f62ce4de880MD52icict/511192022-02-09 14:50:01.595oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-02-09T17:50:01Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Relapse in leprosy and drug resistance assessment in a tertiary hospital of the state of Espírito Santo, Brazil
title Relapse in leprosy and drug resistance assessment in a tertiary hospital of the state of Espírito Santo, Brazil
spellingShingle Relapse in leprosy and drug resistance assessment in a tertiary hospital of the state of Espírito Santo, Brazil
Chagas, Danielle Ferreira
Hanseníase
Recorrência
Epidemiologia
Resistência a droga
Leprosy
Recurrence
Epidemiology
Drug resistance
title_short Relapse in leprosy and drug resistance assessment in a tertiary hospital of the state of Espírito Santo, Brazil
title_full Relapse in leprosy and drug resistance assessment in a tertiary hospital of the state of Espírito Santo, Brazil
title_fullStr Relapse in leprosy and drug resistance assessment in a tertiary hospital of the state of Espírito Santo, Brazil
title_full_unstemmed Relapse in leprosy and drug resistance assessment in a tertiary hospital of the state of Espírito Santo, Brazil
title_sort Relapse in leprosy and drug resistance assessment in a tertiary hospital of the state of Espírito Santo, Brazil
author Chagas, Danielle Ferreira
author_facet Chagas, Danielle Ferreira
Diniz, Lucia Martins
Lucas, Elton Almeida
Moraes, Milton Ozório de
author_role author
author2 Diniz, Lucia Martins
Lucas, Elton Almeida
Moraes, Milton Ozório de
author2_role author
author
author
dc.contributor.author.fl_str_mv Chagas, Danielle Ferreira
Diniz, Lucia Martins
Lucas, Elton Almeida
Moraes, Milton Ozório de
dc.subject.other.pt_BR.fl_str_mv Hanseníase
Recorrência
Epidemiologia
Resistência a droga
topic Hanseníase
Recorrência
Epidemiologia
Resistência a droga
Leprosy
Recurrence
Epidemiology
Drug resistance
dc.subject.en.pt_BR.fl_str_mv Leprosy
Recurrence
Epidemiology
Drug resistance
description Universidade Federal do Espirito Santo. Hospital Universitário Cassiano Antônio Morais. Serviço de Dermatologia. Vitória, ES, Brasil.
publishDate 2021
dc.date.issued.fl_str_mv 2021
dc.date.accessioned.fl_str_mv 2022-02-09T17:50:01Z
dc.date.available.fl_str_mv 2022-02-09T17:50:01Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv CHAGAS, Danielle Ferreira et al. Relapse in leprosy and drug resistance assessment in a tertiary hospital of the state of Espírito Santo, Brazil. Revista da Sociedade Brasileira de Medicina Tropical, v. 54, e0375-2020, p. 1 - 4, 2021.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/51119
dc.identifier.issn.pt_BR.fl_str_mv 1678-9849
dc.identifier.doi.none.fl_str_mv 10.1590/0037-8682-0375-2020
identifier_str_mv CHAGAS, Danielle Ferreira et al. Relapse in leprosy and drug resistance assessment in a tertiary hospital of the state of Espírito Santo, Brazil. Revista da Sociedade Brasileira de Medicina Tropical, v. 54, e0375-2020, p. 1 - 4, 2021.
1678-9849
10.1590/0037-8682-0375-2020
url https://www.arca.fiocruz.br/handle/icict/51119
dc.language.iso.fl_str_mv eng
language eng
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dc.publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical
publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
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instacron_str FIOCRUZ
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collection Repositório Institucional da FIOCRUZ (ARCA)
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https://www.arca.fiocruz.br/bitstream/icict/51119/2/MiltonMoraes_DanielleChagas_etal_IOC_2021.pdf
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