Brainstem dysfunction in critically ill patients

Detalhes bibliográficos
Autor(a) principal: Benghanem, Sarah
Data de Publicação: 2020
Outros Autores: Mazeraud, Aurélien, Azabou, Eric, Chhor, Vibol, Shinotsuka, Cassia Righy, Claassen, Jan, Rohaut, Benjamin, Sharshar, Tarek
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/40394
Resumo: Department of Neurology, Neuro-ICU, Sorbonne University, APHP Pitié-Salpêtrière Hospital, Paris, France./ Medical ICU, Cochin Hospital, AP-HP, Paris, France.
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spelling Benghanem, SarahMazeraud, AurélienAzabou, EricChhor, VibolShinotsuka, Cassia RighyClaassen, JanRohaut, BenjaminSharshar, Tarek2020-03-18T19:16:15Z2020-03-18T19:16:15Z2020BENGHANEM, Sarah et al. Brainstem dysfunction in critically ill patients. Critical care (London, England) v. 24, n. 1, p. 5, 2020.1364-8535https://www.arca.fiocruz.br/handle/icict/4039410.1186/s13054-019-2718-9engBMCBrainstem dysfunction in critically ill patientsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleDepartment of Neurology, Neuro-ICU, Sorbonne University, APHP Pitié-Salpêtrière Hospital, Paris, France./ Medical ICU, Cochin Hospital, AP-HP, Paris, France.Department of Neuro-ICU, GHU-Paris, Paris-Descartes University, Paris, France./ Laboratory of Experimental Neuropathology, Pastuer Institute, Paris, France.Department of Physiology, Clinical Neurophysiology Unit, APHP, Raymond Poincaré Hospital, University of Versailles Saint Quentin en Yvelines, Garches, France.Department of Intensive Care Medicine, Saint-Joseph Hospital, Paris, France.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em Medicina Intensiva./ Intensive Care Unit and Postgraduate Program, Instituto Nacional de Câncer./ D'Or Institute for Research and Education, Rio de Janeiro, RJ, Brasil.Department of Neurology, Neuro-ICU, Columbia University, New York, NY, USA.Department of Neurology, Neuro-ICU, Sorbonne University, APHP Pitié-Salpêtrière Hospital, Paris, France./ Department of Neurology, Neuro-ICU, Columbia University, New York, NY, USA./ Institut du Cerveau et de la Moelle épinière, ICM, INSERM UMRS 1127, CNRS UMR 7225, Pitié- Salpêtrière Hospital, Paris, France.Department of Neuro-ICU, GHU-Paris, Paris-Descartes University, Paris, France./ Laboratory of Experimental Neuropathology, Pastuer Institute, Paris, France.The brainstem conveys sensory and motor inputs between the spinal cord and the brain, and contains nuclei of the cranial nerves. It controls the sleep-wake cycle and vital functions via the ascending reticular activating system and the autonomic nuclei, respectively. Brainstem dysfunction may lead to sensory and motor deficits, cranial nerve palsies, impairment of consciousness, dysautonomia, and respiratory failure. The brainstem is prone to various primary and secondary insults, resulting in acute or chronic dysfunction. Of particular importance for characterizing brainstem dysfunction and identifying the underlying etiology are a detailed clinical examination, MRI, neurophysiologic tests such as brainstem auditory evoked potentials, and an analysis of the cerebrospinal fluid. Detection of brainstem dysfunction is challenging but of utmost importance in comatose and deeply sedated patients both to guide therapy and to support outcome prediction. In the present review, we summarize the neuroanatomy, clinical syndromes, and diagnostic techniques of critical illness-associated brainstem dysfunction for the critical care setting.Brainstem dysfunctionBrain injured patientsIntensive care unitSedationBrainstem reflexesDisorders of consciousnessAutonomic nervous systemNeurological respiratory failureImmune reflexAuditory and somatosensory evoked potentials and electroencephalograminfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; 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dc.title.pt_BR.fl_str_mv Brainstem dysfunction in critically ill patients
title Brainstem dysfunction in critically ill patients
spellingShingle Brainstem dysfunction in critically ill patients
Benghanem, Sarah
Brainstem dysfunction
Brain injured patients
Intensive care unit
Sedation
Brainstem reflexes
Disorders of consciousness
Autonomic nervous system
Neurological respiratory failure
Immune reflex
Auditory and somatosensory evoked potentials and electroencephalogram
title_short Brainstem dysfunction in critically ill patients
title_full Brainstem dysfunction in critically ill patients
title_fullStr Brainstem dysfunction in critically ill patients
title_full_unstemmed Brainstem dysfunction in critically ill patients
title_sort Brainstem dysfunction in critically ill patients
author Benghanem, Sarah
author_facet Benghanem, Sarah
Mazeraud, Aurélien
Azabou, Eric
Chhor, Vibol
Shinotsuka, Cassia Righy
Claassen, Jan
Rohaut, Benjamin
Sharshar, Tarek
author_role author
author2 Mazeraud, Aurélien
Azabou, Eric
Chhor, Vibol
Shinotsuka, Cassia Righy
Claassen, Jan
Rohaut, Benjamin
Sharshar, Tarek
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Benghanem, Sarah
Mazeraud, Aurélien
Azabou, Eric
Chhor, Vibol
Shinotsuka, Cassia Righy
Claassen, Jan
Rohaut, Benjamin
Sharshar, Tarek
dc.subject.en.pt_BR.fl_str_mv Brainstem dysfunction
Brain injured patients
Intensive care unit
Sedation
Brainstem reflexes
Disorders of consciousness
Autonomic nervous system
Neurological respiratory failure
Immune reflex
Auditory and somatosensory evoked potentials and electroencephalogram
topic Brainstem dysfunction
Brain injured patients
Intensive care unit
Sedation
Brainstem reflexes
Disorders of consciousness
Autonomic nervous system
Neurological respiratory failure
Immune reflex
Auditory and somatosensory evoked potentials and electroencephalogram
description Department of Neurology, Neuro-ICU, Sorbonne University, APHP Pitié-Salpêtrière Hospital, Paris, France./ Medical ICU, Cochin Hospital, AP-HP, Paris, France.
publishDate 2020
dc.date.accessioned.fl_str_mv 2020-03-18T19:16:15Z
dc.date.available.fl_str_mv 2020-03-18T19:16:15Z
dc.date.issued.fl_str_mv 2020
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv BENGHANEM, Sarah et al. Brainstem dysfunction in critically ill patients. Critical care (London, England) v. 24, n. 1, p. 5, 2020.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/40394
dc.identifier.issn.pt_BR.fl_str_mv 1364-8535
dc.identifier.doi.none.fl_str_mv 10.1186/s13054-019-2718-9
identifier_str_mv BENGHANEM, Sarah et al. Brainstem dysfunction in critically ill patients. Critical care (London, England) v. 24, n. 1, p. 5, 2020.
1364-8535
10.1186/s13054-019-2718-9
url https://www.arca.fiocruz.br/handle/icict/40394
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv BMC
publisher.none.fl_str_mv BMC
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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