Hepatitis B and C prevalences among blood donors in the south region of Brazil

Detalhes bibliográficos
Autor(a) principal: Vasconcelos, H. C. F. F.
Data de Publicação: 1994
Outros Autores: Yoshida, C. F. T., Vanderborght, B. O. M., Schatzmayr, H. G.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/43665
Resumo: Centro de Hematologia e Hemoterapia de Santa Catarina-HEMOSC. Setor de Sorologia. Florianópolis, SC, Brasil.
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spelling Vasconcelos, H. C. F. F.Yoshida, C. F. T.Vanderborght, B. O. M.Schatzmayr, H. G.2020-09-28T19:50:03Z2020-09-28T19:50:03Z1994VASCONCELOS, H. C. F. F. et al. Hepatitis B and C prevalences among blood donors in the south region of Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 89, n. 4, p. 503-507, Oct. Dec. 1994.0074-0276https://www.arca.fiocruz.br/handle/icict/4366510.1590/S0074-027619940004000021678-8060engFundação Oswaldo Cruz. Instituto Oswaldo Cruz.Doadores de sangueHepatite CHepatite Banti-HBcanti-HBcAlanina aminotransferaseBlood donorsHapatitis CHapatitis BAlanine aminotransferaseanti-HBcanti-HBcHepatitis B and C prevalences among blood donors in the south region of Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleCentro de Hematologia e Hemoterapia de Santa Catarina-HEMOSC. Setor de Sorologia. Florianópolis, SC, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil.Innogenetics N. V, Gent. Belgium.Centro de Hematologia e Hemoterapia de Santa Catarina-HEMOSC. Setor de Sorologia. Florianópolis, SC, Brasil.The prevalence of hepatitis B and C infection has been determined in a seroepidemiological survey among blood donors from the south of Brazil (Florianópolis, State of Santa Catarina). These markers has also been correlated with the levels of alanine aminotransferase (ALT), a surrogate marker to prevent post-transfusion hepatitis. Sera from 5000 donors were randomly collected in the period of April to November 1991. The prevalences of HBsAg, anti-HBs and anti-HBc were respectively 0.78, 7.02 and 13.98. The anti-HCV prevalence after confirmation testing with line immunoassay (LIA), was 1.14. Normal values of ALT ( < = 32 U/ml) were found in 59.78, values slightly above the mean (ALT between 32-70 U/ml) in 37.74 and high values of ALT ( > = 70 U/ml) in 2.48. The positivity of anti-HCV antibodies increased with the elevation of ALT levels. This correlation was not observed in relation to HBsAg. There exists a diversity in the recognition of HCV epitopes among HCV positive donors. Via the confirmation test used, we could observe that 94.7 of donors recognize the structural core antigen. Besides that, we observed that 5.26 of the HCV reactive sera recognized only epitopes located in the NS4 and/or NS5 region, indicating the importance of these epitopes for the improvement of assays.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/43665/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALHCFFVasconcelos_HGSharzmayr_IOC_1994.pdfHCFFVasconcelos_HGSharzmayr_IOC_1994.pdfapplication/pdf236719https://www.arca.fiocruz.br/bitstream/icict/43665/2/HCFFVasconcelos_HGSharzmayr_IOC_1994.pdfdd1361cae60e970e18450231ef05e346MD52TEXTHCFFVasconcelos_HGSharzmayr_IOC_1994.pdf.txtHCFFVasconcelos_HGSharzmayr_IOC_1994.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Hepatitis B and C prevalences among blood donors in the south region of Brazil
title Hepatitis B and C prevalences among blood donors in the south region of Brazil
spellingShingle Hepatitis B and C prevalences among blood donors in the south region of Brazil
Vasconcelos, H. C. F. F.
Doadores de sangue
Hepatite C
Hepatite B
anti-HBc
anti-HBc
Alanina aminotransferase
Blood donors
Hapatitis C
Hapatitis B
Alanine aminotransferase
anti-HBc
anti-HBc
title_short Hepatitis B and C prevalences among blood donors in the south region of Brazil
title_full Hepatitis B and C prevalences among blood donors in the south region of Brazil
title_fullStr Hepatitis B and C prevalences among blood donors in the south region of Brazil
title_full_unstemmed Hepatitis B and C prevalences among blood donors in the south region of Brazil
title_sort Hepatitis B and C prevalences among blood donors in the south region of Brazil
author Vasconcelos, H. C. F. F.
author_facet Vasconcelos, H. C. F. F.
Yoshida, C. F. T.
Vanderborght, B. O. M.
Schatzmayr, H. G.
author_role author
author2 Yoshida, C. F. T.
Vanderborght, B. O. M.
Schatzmayr, H. G.
author2_role author
author
author
dc.contributor.author.fl_str_mv Vasconcelos, H. C. F. F.
Yoshida, C. F. T.
Vanderborght, B. O. M.
Schatzmayr, H. G.
dc.subject.other.pt_BR.fl_str_mv Doadores de sangue
Hepatite C
Hepatite B
anti-HBc
anti-HBc
Alanina aminotransferase
topic Doadores de sangue
Hepatite C
Hepatite B
anti-HBc
anti-HBc
Alanina aminotransferase
Blood donors
Hapatitis C
Hapatitis B
Alanine aminotransferase
anti-HBc
anti-HBc
dc.subject.en.pt_BR.fl_str_mv Blood donors
Hapatitis C
Hapatitis B
Alanine aminotransferase
anti-HBc
anti-HBc
description Centro de Hematologia e Hemoterapia de Santa Catarina-HEMOSC. Setor de Sorologia. Florianópolis, SC, Brasil.
publishDate 1994
dc.date.issued.fl_str_mv 1994
dc.date.accessioned.fl_str_mv 2020-09-28T19:50:03Z
dc.date.available.fl_str_mv 2020-09-28T19:50:03Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv VASCONCELOS, H. C. F. F. et al. Hepatitis B and C prevalences among blood donors in the south region of Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 89, n. 4, p. 503-507, Oct. Dec. 1994.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/43665
dc.identifier.issn.pt_BR.fl_str_mv 0074-0276
dc.identifier.doi.none.fl_str_mv 10.1590/S0074-02761994000400002
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv VASCONCELOS, H. C. F. F. et al. Hepatitis B and C prevalences among blood donors in the south region of Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 89, n. 4, p. 503-507, Oct. Dec. 1994.
0074-0276
10.1590/S0074-02761994000400002
1678-8060
url https://www.arca.fiocruz.br/handle/icict/43665
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
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reponame_str Repositório Institucional da FIOCRUZ (ARCA)
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