High prevalence of parvovirus B19 infection in patients with chronic kidney disease under hemodialysis: a multicenter study

Detalhes bibliográficos
Autor(a) principal: Alves, Arthur Daniel Rocha
Data de Publicação: 2020
Outros Autores: Langella, Barbara Barbosa, Barbosa, Jakeline Ribeiro, Lima, Danielle Malta, Colares, Jeová Keny Baima, Garcia, Rita de Cassia Nasser Cubel, Pinto, Marcelo Alves, Villar, Livia Melo, Amado, Luciane Almeida
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/44093
Resumo: Instituto Oswaldo Cruz/ Fundação Oswaldo Cruz e Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.
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spelling Alves, Arthur Daniel RochaLangella, Barbara BarbosaBarbosa, Jakeline RibeiroLima, Danielle MaltaColares, Jeová Keny BaimaGarcia, Rita de Cassia Nasser CubelPinto, Marcelo AlvesVillar, Livia MeloAmado, Luciane Almeida2020-10-20T18:50:58Z2020-10-20T18:50:58Z2020ALVES, Arthur Daniel Rocha et al. High prevalence of parvovirus B19 infection in patients with chronic kidney disease under hemodialysis: a multicenter study. International Journal of Infectious Diseases, [Hamilton], v. 100, p. 350-356, 2020.1201-9712https://www.arca.fiocruz.br/handle/icict/4409310.1016/j.ijid.2020.09.010Instituto Oswaldo Cruz/ Fundação Oswaldo Cruz e Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Desenvolvimento Tecnológico em Virologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Desenvolvimento Tecnológico em Virologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Fiocruz Brasília. Brasília, DF, Brasil.Universidade de Fortaleza. Fortaleza, CE, Brasil.Universidade de Fortaleza. Fortaleza, CE, Brasil.Universidade Federal Fluminense. Instituto Biomédico. Departamento de Microbiologia e Parasitologia. Niterói, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Desenvolvimento Tecnológico em Virologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Desenvolvimento Tecnológico em Virologia. Rio de Janeiro, RJ, Brasil.Objectives: Parvovirus B19 (B19V) infection is commonly acute and self-limited, but in chronic kidney disease (CKD) patients under dialysis treatment, this infection could increase susceptibility to acute and chronic anemia. The aim of this study was to evaluate the frequency and risk of B19V infection among Brazilian CKD patients under dialysis. Methods: A study was conducted among 221 CKD patients and a control group of 142 blood donors. B19V infection was evaluated in serum samples by real-time PCR, and ELISA (anti-B19V IgM and IgG). Results: B19V DNA was detected in 65% (145/221) of CKD patients, which was significantly higher (p < 0.001) than in the blood donors (6.3%). Simultaneous detection of B19V IgG and viremia was shown in 40.3% of CKD patients, which was indicative of persistent B19V infection. CKD patients showed an increased risk of developing B19V infection (OR = 28.1, CI = 13.5–58.5, p = 0.001). Conclusions: Despite an absence of clinical signs of B19V infection, these data highlight the importance of B19V infection in this high-risk population, since a persistent B19V infection could become clinically significant after renal transplant. Moreover, the persistent viremia should be considered as a potential risk, mainly because of the contamination of dialysis equipment.engElsevierParvovirus B19, HumanRenal Insufficiency, ChronicRisk FactorsRenal DialysisChronic kidney diseaseDialysisParvovirus B19PrevalenceRiskParvovirus B19 HumanoInsuficiência Renal CrônicaFatores de RiscoDiálise RenalHigh prevalence of parvovirus B19 infection in patients with chronic kidney disease under hemodialysis: a multicenter studyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; 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dc.title.pt_BR.fl_str_mv High prevalence of parvovirus B19 infection in patients with chronic kidney disease under hemodialysis: a multicenter study
title High prevalence of parvovirus B19 infection in patients with chronic kidney disease under hemodialysis: a multicenter study
spellingShingle High prevalence of parvovirus B19 infection in patients with chronic kidney disease under hemodialysis: a multicenter study
Alves, Arthur Daniel Rocha
Parvovirus B19, Human
Renal Insufficiency, Chronic
Risk Factors
Renal Dialysis
Chronic kidney disease
Dialysis
Parvovirus B19
Prevalence
Risk
Parvovirus B19 Humano
Insuficiência Renal Crônica
Fatores de Risco
Diálise Renal
title_short High prevalence of parvovirus B19 infection in patients with chronic kidney disease under hemodialysis: a multicenter study
title_full High prevalence of parvovirus B19 infection in patients with chronic kidney disease under hemodialysis: a multicenter study
title_fullStr High prevalence of parvovirus B19 infection in patients with chronic kidney disease under hemodialysis: a multicenter study
title_full_unstemmed High prevalence of parvovirus B19 infection in patients with chronic kidney disease under hemodialysis: a multicenter study
title_sort High prevalence of parvovirus B19 infection in patients with chronic kidney disease under hemodialysis: a multicenter study
author Alves, Arthur Daniel Rocha
author_facet Alves, Arthur Daniel Rocha
Langella, Barbara Barbosa
Barbosa, Jakeline Ribeiro
Lima, Danielle Malta
Colares, Jeová Keny Baima
Garcia, Rita de Cassia Nasser Cubel
Pinto, Marcelo Alves
Villar, Livia Melo
Amado, Luciane Almeida
author_role author
author2 Langella, Barbara Barbosa
Barbosa, Jakeline Ribeiro
Lima, Danielle Malta
Colares, Jeová Keny Baima
Garcia, Rita de Cassia Nasser Cubel
Pinto, Marcelo Alves
Villar, Livia Melo
Amado, Luciane Almeida
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Alves, Arthur Daniel Rocha
Langella, Barbara Barbosa
Barbosa, Jakeline Ribeiro
Lima, Danielle Malta
Colares, Jeová Keny Baima
Garcia, Rita de Cassia Nasser Cubel
Pinto, Marcelo Alves
Villar, Livia Melo
Amado, Luciane Almeida
dc.subject.mesh.pt_BR.fl_str_mv Parvovirus B19, Human
Renal Insufficiency, Chronic
Risk Factors
Renal Dialysis
topic Parvovirus B19, Human
Renal Insufficiency, Chronic
Risk Factors
Renal Dialysis
Chronic kidney disease
Dialysis
Parvovirus B19
Prevalence
Risk
Parvovirus B19 Humano
Insuficiência Renal Crônica
Fatores de Risco
Diálise Renal
dc.subject.en.pt_BR.fl_str_mv Chronic kidney disease
Dialysis
Parvovirus B19
Prevalence
Risk
dc.subject.decs.pt_BR.fl_str_mv Parvovirus B19 Humano
Insuficiência Renal Crônica
Fatores de Risco
Diálise Renal
description Instituto Oswaldo Cruz/ Fundação Oswaldo Cruz e Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.
publishDate 2020
dc.date.accessioned.fl_str_mv 2020-10-20T18:50:58Z
dc.date.available.fl_str_mv 2020-10-20T18:50:58Z
dc.date.issued.fl_str_mv 2020
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv ALVES, Arthur Daniel Rocha et al. High prevalence of parvovirus B19 infection in patients with chronic kidney disease under hemodialysis: a multicenter study. International Journal of Infectious Diseases, [Hamilton], v. 100, p. 350-356, 2020.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/44093
dc.identifier.issn.pt_BR.fl_str_mv 1201-9712
dc.identifier.doi.none.fl_str_mv 10.1016/j.ijid.2020.09.010
identifier_str_mv ALVES, Arthur Daniel Rocha et al. High prevalence of parvovirus B19 infection in patients with chronic kidney disease under hemodialysis: a multicenter study. International Journal of Infectious Diseases, [Hamilton], v. 100, p. 350-356, 2020.
1201-9712
10.1016/j.ijid.2020.09.010
url https://www.arca.fiocruz.br/handle/icict/44093
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
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institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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