Histopathological and immunohistochemical studies of infective dermatitis associated with HTLV-I.

Detalhes bibliográficos
Autor(a) principal: Bittencourt, Achilea Candida Lisboa
Data de Publicação: 2005
Outros Autores: Oliveira, Maria de Fátima Santos Paim de, Alves, Carlos Roberto Brites, Van Weyenbergh, Johan Jozef Rosa Maria, Vieira, Maria das Graças Silva, Araújo, Iguaracyra Barreto de Oliveira
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/10798
Resumo: Universidade Federal da Bahia. Hospital Prof. Edgard Santos. Departamento de Patologia e Dermatologia. Salvador, BA, Brasil
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spelling Bittencourt, Achilea Candida LisboaOliveira, Maria de Fátima Santos Paim deAlves, Carlos Roberto BritesVan Weyenbergh, Johan Jozef Rosa MariaVieira, Maria das Graças SilvaAraújo, Iguaracyra Barreto de Oliveira2015-06-11T18:53:25Z2015-06-11T18:53:25Z2005BITTENCOURT, A. C. L. et al. Histopathological and immunohistochemical studies of infective dermatitis associated with HTLV-I. European Journal of Dermatology, v. 15, n. 1, p. 26-30, 2005.1167-1122https://www.arca.fiocruz.br/handle/icict/10798engJohn Libbey Eurotext [Histopathological and immunohistochemical studies of infective dermatitis associated with HTLV-I.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal da Bahia. Hospital Prof. Edgard Santos. Departamento de Patologia e Dermatologia. Salvador, BA, BrasilUniversidade Federal da Bahia. Hospital Prof. Edgard Santos. Laboratório de Retrovirologia. Salvador, BA, Brasilniversidade Federal da Bahia. Hospital Prof. Edgard Santos. Laboratório de Retrovirologia. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Imunoregulação e Microbiologia. Salvador, BA, BrasilUniversidade Federal da Bahia. Hospital Prof. Edgard Santos. Departamento de Patologia. Salvador, BA, BrasilUniversidade Federal da Bahia. Hospital Prof. Edgard Santos. Departamento de Patologia. Salvador, BA, BrasilInfective dermatitis associated with HTLV-I (IDH) is a chronic, recurrent, exudative eczema occurring in childhood which is considered to be a risk factor for the development of lymphoma and HTLV-I-associated myelopathy/tropical spastic paraparesis. Skin biopsies from 19 patients with IDH were studied histologically and immunohistochemically using the following antibodies: anti-CD3, CD45RO, CD20, CD79a, CD4, CD8, CD56, CD57, TIA-1, granzyme-B, and perforin.A chronic dermatitis similar to atopic and seborrheic dermatitis was observed in 15 cases, whereas architectural aspects mimicking mycosis fungoides were observed in the remaining four. The infiltrate consisted predominantly of CD8+ lymphocytes and of CD57+ cells in the dermis and epidermis. TIA-1 and granzyme-B were expressed in 15/18 cases and 5/19 cases at the proportion of ≤ 15% and ≤ 3%, respectively. All cases were negative for perforin and CD56. Like other dermatites, histologically IDH may represent a benign simulator of mycosis fungoides. IDH shows a predominance of CD8+ cells and a low percentage of cells with cytotoxic granules, indicating that most CD8+ lymphocytes are not activated. These findings differ from the immunohistochemical pattern of atopic and seborrheic dermatitis, possibly representing additional means of differentiation between IDH and these dermatites. The distribution of CD57+ cells suggests that they play a role in the inflammatory process.HTLV-I infectionInfective dermatitisInflammatory simulators of mycosis fungoidesPediatric HTLV-I-associated myelopathy/tropical spastic paraparesisDermatite/patologiaDermatite/virologiaInfecções por HTLV-I/patologiaAdolescenteCriançaPré-EscolarFemininoInfecções por HTLV-I/imunologiaDermatite/imunologiaHumanosImuno-HistoquímicaLinfócitosMasculinoinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82380https://www.arca.fiocruz.br/bitstream/icict/10798/1/license.txtc2eac69ca9356b5d755a3eeeda9442cfMD51ORIGINALBittencourt A L Histopathological and immunohistochemical....pdfBittencourt A L Histopathological and immunohistochemical....pdfapplication/pdf258328https://www.arca.fiocruz.br/bitstream/icict/10798/2/Bittencourt%20A%20L%20Histopathological%20and%20immunohistochemical....pdf40a53d44901ec8873c45d3ac7a876af9MD52TEXTBittencourt A L Histopathological and immunohistochemical....pdf.txtBittencourt A L Histopathological and immunohistochemical....pdf.txtExtracted texttext/plain24406https://www.arca.fiocruz.br/bitstream/icict/10798/3/Bittencourt%20A%20L%20Histopathological%20and%20immunohistochemical....pdf.txt6281a1eda2d13873847c657e6cd005b5MD53icict/107982023-03-15 14:33:08.217oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:08Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Histopathological and immunohistochemical studies of infective dermatitis associated with HTLV-I.
title Histopathological and immunohistochemical studies of infective dermatitis associated with HTLV-I.
spellingShingle Histopathological and immunohistochemical studies of infective dermatitis associated with HTLV-I.
Bittencourt, Achilea Candida Lisboa
HTLV-I infection
Infective dermatitis
Inflammatory simulators of mycosis fungoides
Pediatric HTLV-I-associated myelopathy/tropical spastic paraparesis
Dermatite/patologia
Dermatite/virologia
Infecções por HTLV-I/patologia
Adolescente
Criança
Pré-Escolar
Feminino
Infecções por HTLV-I/imunologia
Dermatite/imunologia
Humanos
Imuno-Histoquímica
Linfócitos
Masculino
title_short Histopathological and immunohistochemical studies of infective dermatitis associated with HTLV-I.
title_full Histopathological and immunohistochemical studies of infective dermatitis associated with HTLV-I.
title_fullStr Histopathological and immunohistochemical studies of infective dermatitis associated with HTLV-I.
title_full_unstemmed Histopathological and immunohistochemical studies of infective dermatitis associated with HTLV-I.
title_sort Histopathological and immunohistochemical studies of infective dermatitis associated with HTLV-I.
author Bittencourt, Achilea Candida Lisboa
author_facet Bittencourt, Achilea Candida Lisboa
Oliveira, Maria de Fátima Santos Paim de
Alves, Carlos Roberto Brites
Van Weyenbergh, Johan Jozef Rosa Maria
Vieira, Maria das Graças Silva
Araújo, Iguaracyra Barreto de Oliveira
author_role author
author2 Oliveira, Maria de Fátima Santos Paim de
Alves, Carlos Roberto Brites
Van Weyenbergh, Johan Jozef Rosa Maria
Vieira, Maria das Graças Silva
Araújo, Iguaracyra Barreto de Oliveira
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Bittencourt, Achilea Candida Lisboa
Oliveira, Maria de Fátima Santos Paim de
Alves, Carlos Roberto Brites
Van Weyenbergh, Johan Jozef Rosa Maria
Vieira, Maria das Graças Silva
Araújo, Iguaracyra Barreto de Oliveira
dc.subject.en.pt_BR.fl_str_mv HTLV-I infection
Infective dermatitis
Inflammatory simulators of mycosis fungoides
Pediatric HTLV-I-associated myelopathy/tropical spastic paraparesis
topic HTLV-I infection
Infective dermatitis
Inflammatory simulators of mycosis fungoides
Pediatric HTLV-I-associated myelopathy/tropical spastic paraparesis
Dermatite/patologia
Dermatite/virologia
Infecções por HTLV-I/patologia
Adolescente
Criança
Pré-Escolar
Feminino
Infecções por HTLV-I/imunologia
Dermatite/imunologia
Humanos
Imuno-Histoquímica
Linfócitos
Masculino
dc.subject.decs.pt_BR.fl_str_mv Dermatite/patologia
Dermatite/virologia
Infecções por HTLV-I/patologia
Adolescente
Criança
Pré-Escolar
Feminino
Infecções por HTLV-I/imunologia
Dermatite/imunologia
Humanos
Imuno-Histoquímica
Linfócitos
Masculino
description Universidade Federal da Bahia. Hospital Prof. Edgard Santos. Departamento de Patologia e Dermatologia. Salvador, BA, Brasil
publishDate 2005
dc.date.issued.fl_str_mv 2005
dc.date.accessioned.fl_str_mv 2015-06-11T18:53:25Z
dc.date.available.fl_str_mv 2015-06-11T18:53:25Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv BITTENCOURT, A. C. L. et al. Histopathological and immunohistochemical studies of infective dermatitis associated with HTLV-I. European Journal of Dermatology, v. 15, n. 1, p. 26-30, 2005.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/10798
dc.identifier.issn.none.fl_str_mv 1167-1122
identifier_str_mv BITTENCOURT, A. C. L. et al. Histopathological and immunohistochemical studies of infective dermatitis associated with HTLV-I. European Journal of Dermatology, v. 15, n. 1, p. 26-30, 2005.
1167-1122
url https://www.arca.fiocruz.br/handle/icict/10798
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv John Libbey Eurotext [
publisher.none.fl_str_mv John Libbey Eurotext [
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
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instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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