Genomic integration as a way to stable high producers CHO cells

Detalhes bibliográficos
Autor(a) principal: Kessler, Rafael Luis
Data de Publicação: 2019
Outros Autores: Inoue, Alexandre Haruo, Preti, Henrique, Serpeloni, Mariana, Alcantara, Monica Visnieski, Marchini, Fabricio Klerynton, Krieger, Marco Aurelio
Tipo de documento: Artigo de conferência
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/32710
Resumo: Os autores do resumo não possuem vínculo com a Fiocruz, entretanto, ao submeterem o trabalho no evento organizado por Bio-Manguinhos, cedem automaticamente os direitos à unidade.
id CRUZ_5dc21eda991b9520136a5d06472a6587
oai_identifier_str oai:www.arca.fiocruz.br:icict/32710
network_acronym_str CRUZ
network_name_str Repositório Institucional da FIOCRUZ (ARCA)
repository_id_str 2135
spelling Kessler, Rafael LuisInoue, Alexandre HaruoPreti, HenriqueSerpeloni, MarianaAlcantara, Monica VisnieskiMarchini, Fabricio KleryntonKrieger, Marco Aurelio2019-04-24T13:58:49Z2019-04-24T13:58:49Z2019KESSLER, R. L. et al. Genomic integration as a way to stable high producers CHO cells. In: INTERNATIONAL SYMPOSIUM ON IMMUNOBIOLOGICAL, 4., 2019; SEMINÁRIO ANUAL CIENTÍFICO E TECNOLÓGICO DE BIO-MANGUINHOS, 7., 2019, Rio de Janeiro. Anais... Rio de Janeiro: Bio-Manguinhos, 2019. p. 103.https://www.arca.fiocruz.br/handle/icict/3271010.35259/isi.sact.2019_32710Os autores do resumo não possuem vínculo com a Fiocruz, entretanto, ao submeterem o trabalho no evento organizado por Bio-Manguinhos, cedem automaticamente os direitos à unidade.Os autores externos submeteram sua publicação para apresentação de trabalho no evento “International Symposium on Immunobiologicals”, que foi coordenado e organizado pelo Instituto de Tecnologia em Imunobiológicos (Bio-Manguinhos), da Fundação Oswaldo Cruz.Instituto de Biologia Molecular do Paraná. Curitiba, PR, Brasil.Instituto de Biologia Molecular do Paraná. Curitiba, PR, Brasil.Instituto de Biologia Molecular do Paraná. Curitiba, PR, Brasil.Instituto de Biologia Molecular do Paraná. Curitiba, PR, Brasil.Instituto de Biologia Molecular do Paraná. Curitiba, PR, Brasil.Instituto de Biologia Molecular do Paraná. Curitiba, PR, Brasil.Instituto de Biologia Molecular do Paraná. Curitiba, PR, Brasil.engFiocruz/Instituto de Tecnologia em ImunobiológicosProteína TerapêuticaCélulas CHOSistema de expressãoTherapeutic proteinCHO cellExpression systemCélulas CHOGenomic integration as a way to stable high producers CHO cellsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/32710/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALBIO_18.pdfapplication/pdf48193https://www.arca.fiocruz.br/bitstream/icict/32710/2/BIO_18.pdf076f339d1db44e817ba406d1dc86e68eMD52TEXTBIO_18.pdf.txtBIO_18.pdf.txtExtracted texttext/plain2635https://www.arca.fiocruz.br/bitstream/icict/32710/3/BIO_18.pdf.txtb13dde7736a841b693461e4eecd52b2cMD53icict/327102023-04-26 17:00:35.49oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-04-26T20:00:35Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Genomic integration as a way to stable high producers CHO cells
title Genomic integration as a way to stable high producers CHO cells
spellingShingle Genomic integration as a way to stable high producers CHO cells
Kessler, Rafael Luis
Proteína Terapêutica
Células CHO
Sistema de expressão
Therapeutic protein
CHO cell
Expression system
Células CHO
title_short Genomic integration as a way to stable high producers CHO cells
title_full Genomic integration as a way to stable high producers CHO cells
title_fullStr Genomic integration as a way to stable high producers CHO cells
title_full_unstemmed Genomic integration as a way to stable high producers CHO cells
title_sort Genomic integration as a way to stable high producers CHO cells
author Kessler, Rafael Luis
author_facet Kessler, Rafael Luis
Inoue, Alexandre Haruo
Preti, Henrique
Serpeloni, Mariana
Alcantara, Monica Visnieski
Marchini, Fabricio Klerynton
Krieger, Marco Aurelio
author_role author
author2 Inoue, Alexandre Haruo
Preti, Henrique
Serpeloni, Mariana
Alcantara, Monica Visnieski
Marchini, Fabricio Klerynton
Krieger, Marco Aurelio
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Kessler, Rafael Luis
Inoue, Alexandre Haruo
Preti, Henrique
Serpeloni, Mariana
Alcantara, Monica Visnieski
Marchini, Fabricio Klerynton
Krieger, Marco Aurelio
dc.subject.other.pt_BR.fl_str_mv Proteína Terapêutica
Células CHO
Sistema de expressão
topic Proteína Terapêutica
Células CHO
Sistema de expressão
Therapeutic protein
CHO cell
Expression system
Células CHO
dc.subject.en.pt_BR.fl_str_mv Therapeutic protein
CHO cell
Expression system
dc.subject.decs.pt_BR.fl_str_mv Células CHO
description Os autores do resumo não possuem vínculo com a Fiocruz, entretanto, ao submeterem o trabalho no evento organizado por Bio-Manguinhos, cedem automaticamente os direitos à unidade.
publishDate 2019
dc.date.accessioned.fl_str_mv 2019-04-24T13:58:49Z
dc.date.available.fl_str_mv 2019-04-24T13:58:49Z
dc.date.issued.fl_str_mv 2019
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/conferenceObject
format conferenceObject
status_str publishedVersion
dc.identifier.citation.fl_str_mv KESSLER, R. L. et al. Genomic integration as a way to stable high producers CHO cells. In: INTERNATIONAL SYMPOSIUM ON IMMUNOBIOLOGICAL, 4., 2019; SEMINÁRIO ANUAL CIENTÍFICO E TECNOLÓGICO DE BIO-MANGUINHOS, 7., 2019, Rio de Janeiro. Anais... Rio de Janeiro: Bio-Manguinhos, 2019. p. 103.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/32710
dc.identifier.doi.none.fl_str_mv 10.35259/isi.sact.2019_32710
identifier_str_mv KESSLER, R. L. et al. Genomic integration as a way to stable high producers CHO cells. In: INTERNATIONAL SYMPOSIUM ON IMMUNOBIOLOGICAL, 4., 2019; SEMINÁRIO ANUAL CIENTÍFICO E TECNOLÓGICO DE BIO-MANGUINHOS, 7., 2019, Rio de Janeiro. Anais... Rio de Janeiro: Bio-Manguinhos, 2019. p. 103.
10.35259/isi.sact.2019_32710
url https://www.arca.fiocruz.br/handle/icict/32710
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fiocruz/Instituto de Tecnologia em Imunobiológicos
publisher.none.fl_str_mv Fiocruz/Instituto de Tecnologia em Imunobiológicos
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/32710/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/32710/2/BIO_18.pdf
https://www.arca.fiocruz.br/bitstream/icict/32710/3/BIO_18.pdf.txt
bitstream.checksum.fl_str_mv 8a4605be74aa9ea9d79846c1fba20a33
076f339d1db44e817ba406d1dc86e68e
b13dde7736a841b693461e4eecd52b2c
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
_version_ 1813008903943749632