Antifungal and antioxidant activity of fatty acid methyl esters from vegetable oils.
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/25468 |
Resumo: | 2020-01-01 |
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Pinto, Maria E.A.Araújo, Sthéfane GomesMorais, Marcela I.Sá, Nívea P.Lima, Caroline M.Rosa, Carlos A.Siqueira Filho, Ezequias Pessoa deJohann, SusanaLima, Luciana A.R.S.2018-03-22T15:56:44Z2018-03-22T15:56:44Z2017PINTO, Maria E.A. et al. Antifungal and antioxidant activity of fatty acid methyl esters from vegetable oils. An. Acad. Bras. Ciênc., v. 89, n. 3, p. 1671-1681, 2017.0001-3765https://www.arca.fiocruz.br/handle/icict/2546810.1590/0001-3765201720160908engAcademia Brasileira de Ciênciasanti fungosantioxidantesoleos vegetaisantifungalantioxidantfatty acid methyl estersvegetable oilsAntifungal and antioxidant activity of fatty acid methyl esters from vegetable oils.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2020-01-01Universidade Federal de São João Del Rei. Divinópolis, MG, BrazilUniversidade Federal de São João Del Rei. Divinópolis, MG, BrazilUniversidade Federal de São João Del Rei. Divinópolis, MG, BrazilUniversidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Microbiologia. Belo Horizonte, MG, BrazilUniversidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Microbiologia. Belo Horizonte, MG, BrazilUniversidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Microbiologia. Belo Horizonte, MG, BrazilFundação Oswaldo Cruz. Instituto Rene Rachou. René Rachou. Belo Horizonte, MG, BrazilUniversidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Microbiologia. Belo Horizonte, MG, BrazilUniversidade Federal de São João Del Rei. Divinópolis, MG, BrazilFatty acid methyl esters (FAMEs) were obtained from vegetable oils of soybean, corn and sunflower. The current study was focused on evaluating the antifungal activity of FAMEs mainly against Paracoccidioides spp., as well as testing the interaction of these compounds with commercial antifungal drugs and also their antioxidant potential. FAMEs presented small IC50 values (1.86-9.42 μg/mL). All three FAMEs tested showed antifungal activity against isolates of Paracoccidioides spp. with MIC values ranging from 15.6-500 µg/mL. Sunflower FAMEs exhibited antifungal activity that extended also to other genera, with an MIC of 15.6 μg/mL against Candida glabrata and C. krusei and 31.2 μg/mL against C. parapsilosis. FAMEs exhibited a synergetic effect with itraconazole. The antifungal activity of the FAMEs against isolates of Paracoccidioides spp. is likely due to the presence of methyl linoleate, the major compound present in all three FAMEs. The results obtained indicate the potential of FAMEs as sources for antifungal and antioxidant activity.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83082https://www.arca.fiocruz.br/bitstream/icict/25468/1/license.txt9193a7c197bc67acd023525e72a03240MD51ORIGINALAntifungal and antioxidant activity of fatty acid methyl esters from vegetable oils.pdfAntifungal and antioxidant activity of fatty acid methyl esters from vegetable oils.pdfapplication/pdf632690https://www.arca.fiocruz.br/bitstream/icict/25468/2/Antifungal%20and%20antioxidant%20activity%20of%20fatty%20acid%20methyl%20esters%20from%20vegetable%20oils.pdf042a1b2676ed88146463bd92d80209e8MD52TEXTAntifungal and antioxidant activity of fatty acid methyl esters from vegetable oils.pdf.txtAntifungal and antioxidant activity of fatty acid methyl esters from vegetable oils.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv |
Antifungal and antioxidant activity of fatty acid methyl esters from vegetable oils. |
title |
Antifungal and antioxidant activity of fatty acid methyl esters from vegetable oils. |
spellingShingle |
Antifungal and antioxidant activity of fatty acid methyl esters from vegetable oils. Pinto, Maria E.A. anti fungos antioxidantes oleos vegetais antifungal antioxidant fatty acid methyl esters vegetable oils |
title_short |
Antifungal and antioxidant activity of fatty acid methyl esters from vegetable oils. |
title_full |
Antifungal and antioxidant activity of fatty acid methyl esters from vegetable oils. |
title_fullStr |
Antifungal and antioxidant activity of fatty acid methyl esters from vegetable oils. |
title_full_unstemmed |
Antifungal and antioxidant activity of fatty acid methyl esters from vegetable oils. |
title_sort |
Antifungal and antioxidant activity of fatty acid methyl esters from vegetable oils. |
author |
Pinto, Maria E.A. |
author_facet |
Pinto, Maria E.A. Araújo, Sthéfane Gomes Morais, Marcela I. Sá, Nívea P. Lima, Caroline M. Rosa, Carlos A. Siqueira Filho, Ezequias Pessoa de Johann, Susana Lima, Luciana A.R.S. |
author_role |
author |
author2 |
Araújo, Sthéfane Gomes Morais, Marcela I. Sá, Nívea P. Lima, Caroline M. Rosa, Carlos A. Siqueira Filho, Ezequias Pessoa de Johann, Susana Lima, Luciana A.R.S. |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Pinto, Maria E.A. Araújo, Sthéfane Gomes Morais, Marcela I. Sá, Nívea P. Lima, Caroline M. Rosa, Carlos A. Siqueira Filho, Ezequias Pessoa de Johann, Susana Lima, Luciana A.R.S. |
dc.subject.other.pt_BR.fl_str_mv |
anti fungos antioxidantes oleos vegetais |
topic |
anti fungos antioxidantes oleos vegetais antifungal antioxidant fatty acid methyl esters vegetable oils |
dc.subject.en.pt_BR.fl_str_mv |
antifungal antioxidant fatty acid methyl esters vegetable oils |
description |
2020-01-01 |
publishDate |
2017 |
dc.date.issued.fl_str_mv |
2017 |
dc.date.accessioned.fl_str_mv |
2018-03-22T15:56:44Z |
dc.date.available.fl_str_mv |
2018-03-22T15:56:44Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
PINTO, Maria E.A. et al. Antifungal and antioxidant activity of fatty acid methyl esters from vegetable oils. An. Acad. Bras. Ciênc., v. 89, n. 3, p. 1671-1681, 2017. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/25468 |
dc.identifier.issn.pt_BR.fl_str_mv |
0001-3765 |
dc.identifier.doi.none.fl_str_mv |
10.1590/0001-3765201720160908 |
identifier_str_mv |
PINTO, Maria E.A. et al. Antifungal and antioxidant activity of fatty acid methyl esters from vegetable oils. An. Acad. Bras. Ciênc., v. 89, n. 3, p. 1671-1681, 2017. 0001-3765 10.1590/0001-3765201720160908 |
url |
https://www.arca.fiocruz.br/handle/icict/25468 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Ciências |
publisher.none.fl_str_mv |
Academia Brasileira de Ciências |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
instacron_str |
FIOCRUZ |
institution |
FIOCRUZ |
reponame_str |
Repositório Institucional da FIOCRUZ (ARCA) |
collection |
Repositório Institucional da FIOCRUZ (ARCA) |
bitstream.url.fl_str_mv |
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