Diagnosis of Chagas disease: what has been achieved? What remains to be done with regard to diagnosis and follow up studies?

Detalhes bibliográficos
Autor(a) principal: Gomes, Yara M.
Data de Publicação: 2009
Outros Autores: Lorena, Virginia M. B., Luquetti, Alejandro O.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/27192
Resumo: Biomanguinhos-Fiocruz (CC 09/2007), PDTSP-Fiocruz (PCL04), CNPq (YMG 306427/2006-0), VMBL (143023/2006-3)
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spelling Gomes, Yara M.Lorena, Virginia M. B.Luquetti, Alejandro O.2018-06-29T13:56:38Z2018-06-29T13:56:38Z2009GOMES, Y. M.; LORENA, V. M. B.; LUQUETTI, A. O. Diagnosis of Chagas disease: what has been achieved? What remains to be done with regard to diagnosis and follow up studies? Memorias Do Instituto Oswaldo Cruz, v. 104 Suppl 1, p. 115–121, jul. 2009.1678-8060https://www.arca.fiocruz.br/handle/icict/2719210.1590/S0074-02762009000900017Biomanguinhos-Fiocruz (CC 09/2007), PDTSP-Fiocruz (PCL04), CNPq (YMG 306427/2006-0), VMBL (143023/2006-3)Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Imunologia. Laboratório de Imunoparasitologia. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Imunologia. Laboratório de Imunoparasitologia. Recife, PE, Brasil.Universidade Federal de Goiás. Hospital das Clínicas. Goiânia, GO, Brasil.In the acute phase and in the chronic forms of Chagas disease, the etiological diagnosis may be performed by detection of the parasite using direct or indirect parasitological methods and by the presence of antibodies in the serum by way of serological tests. Several techniques are easily available, ranging from the simplest wet smear preparation to immuno-enzymatic assays with recombinant antigens that will meet most diagnostic needs. Other tests under evaluation include a molecular test using polymerase chain reaction, which has shown promising results and may be used as a confirmatory test both in the acute and chronic phases of the disease. Better rapid tests are needed for diagnosis, some of which are already under evaluation. Additionally, there is a need for tools that can identify patients cured shortly after specific treatment. Other needs include a marker for prognosis and early diagnosis of congenital transmission.engDoença de ChagasTrypanosoma cruziDiagnóstico etiológicoChagas diseaseTrypanosoma cruziEtiological diagnosisDoença AgudaAnticorpos, protozoários / sangueDoença de Chagas / diagnósticoDoença de Chagas / quimioterapiaDoença crônicaEnsaio de Imunoadsorção EnzimáticaHumanosImunoblottingReação em Cadeia da PolimeraseSensibilidade e EspecificidadeTestes SorológicosTripanocidas Agentes / uso terapêuticoTrypanosoma cruzi / genéticaTrypanosoma cruzi / imunologiaDiagnosis of Chagas disease: what has been achieved? What remains to be done with regard to diagnosis and follow up studies?info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83092https://www.arca.fiocruz.br/bitstream/icict/27192/1/license.txt447f2497af1ef5cf99b5c07f6fa18dceMD51ORIGINALdiagnosis of chagas disease.pdfdiagnosis of chagas disease.pdfapplication/pdf802428https://www.arca.fiocruz.br/bitstream/icict/27192/2/diagnosis%20of%20chagas%20disease.pdf6970f76362e2fe33f270cea90496a3f8MD52TEXTdiagnosis of chagas disease.pdf.txtdiagnosis of chagas disease.pdf.txtExtracted texttext/plain44924https://www.arca.fiocruz.br/bitstream/icict/27192/3/diagnosis%20of%20chagas%20disease.pdf.txtfb8820c66f16bf26f3f21f411a0607bcMD53icict/271922018-08-15 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dc.title.pt_BR.fl_str_mv Diagnosis of Chagas disease: what has been achieved? What remains to be done with regard to diagnosis and follow up studies?
title Diagnosis of Chagas disease: what has been achieved? What remains to be done with regard to diagnosis and follow up studies?
spellingShingle Diagnosis of Chagas disease: what has been achieved? What remains to be done with regard to diagnosis and follow up studies?
Gomes, Yara M.
Doença de Chagas
Trypanosoma cruzi
Diagnóstico etiológico
Chagas disease
Trypanosoma cruzi
Etiological diagnosis
Doença Aguda
Anticorpos, protozoários / sangue
Doença de Chagas / diagnóstico
Doença de Chagas / quimioterapia
Doença crônica
Ensaio de Imunoadsorção Enzimática
Humanos
Imunoblotting
Reação em Cadeia da Polimerase
Sensibilidade e Especificidade
Testes Sorológicos
Tripanocidas Agentes / uso terapêutico
Trypanosoma cruzi / genética
Trypanosoma cruzi / imunologia
title_short Diagnosis of Chagas disease: what has been achieved? What remains to be done with regard to diagnosis and follow up studies?
title_full Diagnosis of Chagas disease: what has been achieved? What remains to be done with regard to diagnosis and follow up studies?
title_fullStr Diagnosis of Chagas disease: what has been achieved? What remains to be done with regard to diagnosis and follow up studies?
title_full_unstemmed Diagnosis of Chagas disease: what has been achieved? What remains to be done with regard to diagnosis and follow up studies?
title_sort Diagnosis of Chagas disease: what has been achieved? What remains to be done with regard to diagnosis and follow up studies?
author Gomes, Yara M.
author_facet Gomes, Yara M.
Lorena, Virginia M. B.
Luquetti, Alejandro O.
author_role author
author2 Lorena, Virginia M. B.
Luquetti, Alejandro O.
author2_role author
author
dc.contributor.author.fl_str_mv Gomes, Yara M.
Lorena, Virginia M. B.
Luquetti, Alejandro O.
dc.subject.other.pt_BR.fl_str_mv Doença de Chagas
Trypanosoma cruzi
Diagnóstico etiológico
topic Doença de Chagas
Trypanosoma cruzi
Diagnóstico etiológico
Chagas disease
Trypanosoma cruzi
Etiological diagnosis
Doença Aguda
Anticorpos, protozoários / sangue
Doença de Chagas / diagnóstico
Doença de Chagas / quimioterapia
Doença crônica
Ensaio de Imunoadsorção Enzimática
Humanos
Imunoblotting
Reação em Cadeia da Polimerase
Sensibilidade e Especificidade
Testes Sorológicos
Tripanocidas Agentes / uso terapêutico
Trypanosoma cruzi / genética
Trypanosoma cruzi / imunologia
dc.subject.en.pt_BR.fl_str_mv Chagas disease
Trypanosoma cruzi
Etiological diagnosis
dc.subject.decs.pt_BR.fl_str_mv Doença Aguda
Anticorpos, protozoários / sangue
Doença de Chagas / diagnóstico
Doença de Chagas / quimioterapia
Doença crônica
Ensaio de Imunoadsorção Enzimática
Humanos
Imunoblotting
Reação em Cadeia da Polimerase
Sensibilidade e Especificidade
Testes Sorológicos
Tripanocidas Agentes / uso terapêutico
Trypanosoma cruzi / genética
Trypanosoma cruzi / imunologia
description Biomanguinhos-Fiocruz (CC 09/2007), PDTSP-Fiocruz (PCL04), CNPq (YMG 306427/2006-0), VMBL (143023/2006-3)
publishDate 2009
dc.date.issued.fl_str_mv 2009
dc.date.accessioned.fl_str_mv 2018-06-29T13:56:38Z
dc.date.available.fl_str_mv 2018-06-29T13:56:38Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv GOMES, Y. M.; LORENA, V. M. B.; LUQUETTI, A. O. Diagnosis of Chagas disease: what has been achieved? What remains to be done with regard to diagnosis and follow up studies? Memorias Do Instituto Oswaldo Cruz, v. 104 Suppl 1, p. 115–121, jul. 2009.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/27192
dc.identifier.issn.pt_BR.fl_str_mv 1678-8060
dc.identifier.doi.none.fl_str_mv 10.1590/S0074-02762009000900017
identifier_str_mv GOMES, Y. M.; LORENA, V. M. B.; LUQUETTI, A. O. Diagnosis of Chagas disease: what has been achieved? What remains to be done with regard to diagnosis and follow up studies? Memorias Do Instituto Oswaldo Cruz, v. 104 Suppl 1, p. 115–121, jul. 2009.
1678-8060
10.1590/S0074-02762009000900017
url https://www.arca.fiocruz.br/handle/icict/27192
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
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