Epidemiological and clinical characteristics of the first 557 successive patients with COVID-19 in Pernambuco State, Northeast Brazil

Detalhes bibliográficos
Autor(a) principal: Magalhães, Jurandy Júnior Ferraz de
Data de Publicação: 2020
Outros Autores: Mendes, Renata Pessoa Germano, Silva, Caroline Targino Alves da, Silva, Severino Jefferson Ribeiro da, Guarines, Klarissa Miranda, Pena, Lindomar José
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/43998
Resumo: This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
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spelling Magalhães, Jurandy Júnior Ferraz deMendes, Renata Pessoa GermanoSilva, Caroline Targino Alves daSilva, Severino Jefferson Ribeiro daGuarines, Klarissa MirandaPena, Lindomar José2020-10-15T17:04:32Z2020-10-15T17:04:32Z2020MAGALHÃES, Jurandy Júnior Ferraz de et al. Epidemiological and clinical characteristics of the first 557 successive patients with COVID-19 in Pernambuco State, Northeast Brazil. Travel Medicine and Infectious Disease, p. 1-31, 18 Set. 2020.1477-8939https://www.arca.fiocruz.br/handle/icict/4399810.1016/j.tmaid.2020.101884This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.Other Members of the Pernambuco COVID-29 Research Group: Diego Guerra de Albuquerque Cabral, Jacilane Bezerra da Silva, Valdete Felix de Oliveira, Naishe Matos Freire, Suenia da C. Gonçalves de Albuquerque, Kayk Richardes Araújo Silva, Líliam Vieira de Barros Lima, Patrícia Rodrigues de Oliveira Haver, Anne Maely Maria de Sales Ferreira, Nara Barbosa Araújo, Thassiany Rebeca Paiva Moura da Silva, Leonardo de Aquino Linhares, Keilla Maria Paz e Silva, Rômulo Pessoa e Silva, Ailton de Souza Silva, Liciana Xavier Eurico de Alencar, João Carlos da Silva, Maria José Couto Oliveira, Patricia Michelly Santos Lima, Bárbara Araújo Silva de Azevedo, Roselene Hans Santos.Fundação de Amparo à Ciência e Tecnologia do Estado de PernambucoInternational Development Research Centre (109434)Fiocruz Inova ProgramFundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Virologia e Terapia Experimental. Recife, PE, Brasil / Governo do Estado de Pernambuco. Secretaria Estadual de Saúde. Laboratório Central de Saúde Pública "Dr. Milton Bezerra Sobral". Departamento de Virologia. Recife, PE, Brasil / Universidade de Pernambuco. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Virologia e Terapia Experimental. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Virologia e Terapia Experimental. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Virologia e Terapia Experimental. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Virologia e Terapia Experimental. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Virologia e Terapia Experimental. Recife, PE, Brasil.Background: South America is the current epicenter of COVID-19 pandemic. Yet, the epidemiological and clinical features of the disease have not been described in Brazil, the third most affected country in the world. Methods: In this retrospective study, we describe the demographics, epidemiology and clinical features of the first 557 consecutive patients positive for SARS-CoV-2 living in Pernambuco state, Northeast Brazil. Results: The first COVID-19 cases occurred in the high income population. The age of infected patients ranged from 27 days to 97 years with a median of 47 years. The ratio of males to female in the SARS-CoV-2-infected group was 0.83:1. The most common symptom was cough (74.51%), followed by fever (66.79%), dyspnea (56.01%), sore throat (28.19%) and O2 saturation <95% (24.42%). 86.44% of the lethal cases were patients older than 51 years. The median time from illness onset to diagnosis was 4.0 days (range 0 to 39 days) Severe patients diagnosed after 14 days of symptoms onset had higher viral load than patients with mild disease. Conclusions: Our study provides important information about COVID-19 in the tropics and will assist physicians and health officials to face the current pandemics as SARS-CoV-2 continues to spread in the human population.engElsevierhttps://www.arca.fiocruz.br/handle/icict/52142COVID-19SARS-CoV-2Características clínicasDemografiaEpidemiologiaClínicasCOVID-19SARS-CoV-2Clinical characteristicsDemographicsEpidemiologyClinicsEpidemiological and clinical characteristics of the first 557 successive patients with COVID-19 in Pernambuco State, Northeast Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleSimPublicadoinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83132https://www.arca.fiocruz.br/bitstream/icict/43998/1/license.txt33967fcc8ef681b8f5c2c34178ebc114MD51ORIGINALMagalhães_Jurandy_etal_IAM_2020_COVID-19_PREPRINT.pdfMagalhães_Jurandy_etal_IAM_2020_COVID-19_PREPRINT.pdfapplication/pdf6311011https://www.arca.fiocruz.br/bitstream/icict/43998/2/Magalh%c3%a3es_Jurandy_etal_IAM_2020_COVID-19_PREPRINT.pdfb3794f300a62d5275f0be30893926592MD52Supplementary appendix.docxSupplementary appendix.docxApêndice A - Dados Suplementaresapplication/vnd.openxmlformats-officedocument.wordprocessingml.document38028https://www.arca.fiocruz.br/bitstream/icict/43998/3/Supplementary%20appendix.docx9a780999900c04e79f21461a66beb3a6MD53TEXTMagalhães_Jurandy_etal_IAM_2020_COVID-19_PREPRINT.pdf.txtMagalhães_Jurandy_etal_IAM_2020_COVID-19_PREPRINT.pdf.txtExtracted texttext/plain38694https://www.arca.fiocruz.br/bitstream/icict/43998/4/Magalh%c3%a3es_Jurandy_etal_IAM_2020_COVID-19_PREPRINT.pdf.txt329f8026fb8cc078301d54c7142e6cffMD54icict/439982022-04-10 20:21:39.474oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-04-10T23:21:39Repositório Institucional da FIOCRUZ (ARCA) - 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dc.title.en.fl_str_mv Epidemiological and clinical characteristics of the first 557 successive patients with COVID-19 in Pernambuco State, Northeast Brazil
title Epidemiological and clinical characteristics of the first 557 successive patients with COVID-19 in Pernambuco State, Northeast Brazil
spellingShingle Epidemiological and clinical characteristics of the first 557 successive patients with COVID-19 in Pernambuco State, Northeast Brazil
Magalhães, Jurandy Júnior Ferraz de
COVID-19
SARS-CoV-2
Características clínicas
Demografia
Epidemiologia
Clínicas
COVID-19
SARS-CoV-2
Clinical characteristics
Demographics
Epidemiology
Clinics
title_short Epidemiological and clinical characteristics of the first 557 successive patients with COVID-19 in Pernambuco State, Northeast Brazil
title_full Epidemiological and clinical characteristics of the first 557 successive patients with COVID-19 in Pernambuco State, Northeast Brazil
title_fullStr Epidemiological and clinical characteristics of the first 557 successive patients with COVID-19 in Pernambuco State, Northeast Brazil
title_full_unstemmed Epidemiological and clinical characteristics of the first 557 successive patients with COVID-19 in Pernambuco State, Northeast Brazil
title_sort Epidemiological and clinical characteristics of the first 557 successive patients with COVID-19 in Pernambuco State, Northeast Brazil
author Magalhães, Jurandy Júnior Ferraz de
author_facet Magalhães, Jurandy Júnior Ferraz de
Mendes, Renata Pessoa Germano
Silva, Caroline Targino Alves da
Silva, Severino Jefferson Ribeiro da
Guarines, Klarissa Miranda
Pena, Lindomar José
author_role author
author2 Mendes, Renata Pessoa Germano
Silva, Caroline Targino Alves da
Silva, Severino Jefferson Ribeiro da
Guarines, Klarissa Miranda
Pena, Lindomar José
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Magalhães, Jurandy Júnior Ferraz de
Mendes, Renata Pessoa Germano
Silva, Caroline Targino Alves da
Silva, Severino Jefferson Ribeiro da
Guarines, Klarissa Miranda
Pena, Lindomar José
dc.subject.other.pt_BR.fl_str_mv COVID-19
SARS-CoV-2
Características clínicas
Demografia
Epidemiologia
Clínicas
topic COVID-19
SARS-CoV-2
Características clínicas
Demografia
Epidemiologia
Clínicas
COVID-19
SARS-CoV-2
Clinical characteristics
Demographics
Epidemiology
Clinics
dc.subject.en.en.fl_str_mv COVID-19
SARS-CoV-2
Clinical characteristics
Demographics
Epidemiology
Clinics
description This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
publishDate 2020
dc.date.accessioned.fl_str_mv 2020-10-15T17:04:32Z
dc.date.available.fl_str_mv 2020-10-15T17:04:32Z
dc.date.issued.fl_str_mv 2020
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dc.identifier.citation.fl_str_mv MAGALHÃES, Jurandy Júnior Ferraz de et al. Epidemiological and clinical characteristics of the first 557 successive patients with COVID-19 in Pernambuco State, Northeast Brazil. Travel Medicine and Infectious Disease, p. 1-31, 18 Set. 2020.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/43998
dc.identifier.issn.pt_BR.fl_str_mv 1477-8939
dc.identifier.doi.pt_BR.fl_str_mv 10.1016/j.tmaid.2020.101884
identifier_str_mv MAGALHÃES, Jurandy Júnior Ferraz de et al. Epidemiological and clinical characteristics of the first 557 successive patients with COVID-19 in Pernambuco State, Northeast Brazil. Travel Medicine and Infectious Disease, p. 1-31, 18 Set. 2020.
1477-8939
10.1016/j.tmaid.2020.101884
url https://www.arca.fiocruz.br/handle/icict/43998
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