Characterization of cells recovered from the xenotransplanted NG97 human-derived glioma cell line subcultured in a long-term in vitro
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2008 |
| Outros Autores: | , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/28273 |
Resumo: | Universidade Estadual de Campinas. Instituto de Biologia. Departamento de Microbiologia e Imunologia. Campinas, SP, Brasil. |
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Machado, Camila M. L.Ikemori, Rafael Y.Zorzeto, Tatiana Q.Nogueira, Ana C. M. A.Barbosa, Suse D. S.Savino, WilsonSchenka, André A.Vassallo, JoséHeinrich, Juliana K.Boetcher-Luiz, FátimaVerinaud, Liana2018-08-21T15:05:04Z2018-08-21T15:05:04Z2008MACHADO, Camila M. L. et al. Characterization of cells recovered from the xenotransplanted NG97 human-derived glioma cell line subcultured in a long-term in vitro. BMC Cancer, v.8, n.291, 13p, 2008.1471-2407https://www.arca.fiocruz.br/handle/icict/2827310.1186/1471-2407-8-291engBioMed CentralResistência a MedicamentosProgresso tumoralLinha de células NG97Sistema nervoso centralAstrocitomatumoral progressdrug resistancecultured cell linesNG97 cell lineastrocytomaCentral Nervous SystemCharacterization of cells recovered from the xenotransplanted NG97 human-derived glioma cell line subcultured in a long-term in vitroinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Estadual de Campinas. Instituto de Biologia. Departamento de Microbiologia e Imunologia. Campinas, SP, Brasil.Universidade Estadual de Campinas. Instituto de Biologia. Departamento de Microbiologia e Imunologia. Campinas, SP, Brasil.Universidade Estadual de Campinas. Instituto de Biologia. Departamento de Microbiologia e Imunologia. Campinas, SP, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Controle de Qualidade em Saúde. Departamento de Imunologia. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ. Brasil.Universidade Estadual de Campinas. Faculdade de Ciências Médicas. Laboratório de Pesquisa e Patologia Molecular. Campinas, SP, Brasil.Universidade Estadual de Campinas. Faculdade de Ciências Médicas. Laboratório de Pesquisa e Patologia Molecular. Campinas, SP, Brasil.Universidade Estadual de Campinas. Centro de Atendimento Integral à Saúde da Mulher. Laboratórios Clínicos Especializados. Campinas, SP, Brasil.Universidade Estadual de Campinas. Faculdade de Ciências Médicas. Departamento de Obstetrícia e Ginecologia. Campinas, SP, Brasil.Universidade Estadual de Campinas. Instituto de Biologia. Departamento de Microbiologia e Imunologia. Campinas, SP, Brasil.In order to elucidate tumoral progression and drug resistance, cultured cell lines are valuable tools applied on tumor related assays provided they are well established and characterized. Our laboratory settled the NG97 cell line derived from a human astrocytoma grade III, which started to develop and express important phenotypical characteristics of an astrocytoma grade IV after injection in the flank of nude mice. Astrocytomas are extremely aggressive malignancies of the Central Nervous System (CNS) and account for 46% of all primary malignant brain tumors. Progression to worse prognosis occurs in 85% of the cases possibly due to changes in cell tumor microenvironment and through biological pathways that are still unclear.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/28273/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALsusebarbosa_wilsonsavino_etal_IOC_2008.pdfsusebarbosa_wilsonsavino_etal_IOC_2008.pdfapplication/pdf2042264https://www.arca.fiocruz.br/bitstream/icict/28273/2/susebarbosa_wilsonsavino_etal_IOC_2008.pdf35599d11fc80a25aaf6be090c1b0d7c0MD52TEXTsusebarbosa_wilsonsavino_etal_IOC_2008.pdf.txtsusebarbosa_wilsonsavino_etal_IOC_2008.pdf.txtExtracted texttext/plain48704https://www.arca.fiocruz.br/bitstream/icict/28273/3/susebarbosa_wilsonsavino_etal_IOC_2008.pdf.txt50073dd7a6ac157e6e35f32a72be0c44MD53icict/282732018-08-22 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| dc.title.pt_BR.fl_str_mv |
Characterization of cells recovered from the xenotransplanted NG97 human-derived glioma cell line subcultured in a long-term in vitro |
| title |
Characterization of cells recovered from the xenotransplanted NG97 human-derived glioma cell line subcultured in a long-term in vitro |
| spellingShingle |
Characterization of cells recovered from the xenotransplanted NG97 human-derived glioma cell line subcultured in a long-term in vitro Machado, Camila M. L. Resistência a Medicamentos Progresso tumoral Linha de células NG97 Sistema nervoso central Astrocitoma tumoral progress drug resistance cultured cell lines NG97 cell line astrocytoma Central Nervous System |
| title_short |
Characterization of cells recovered from the xenotransplanted NG97 human-derived glioma cell line subcultured in a long-term in vitro |
| title_full |
Characterization of cells recovered from the xenotransplanted NG97 human-derived glioma cell line subcultured in a long-term in vitro |
| title_fullStr |
Characterization of cells recovered from the xenotransplanted NG97 human-derived glioma cell line subcultured in a long-term in vitro |
| title_full_unstemmed |
Characterization of cells recovered from the xenotransplanted NG97 human-derived glioma cell line subcultured in a long-term in vitro |
| title_sort |
Characterization of cells recovered from the xenotransplanted NG97 human-derived glioma cell line subcultured in a long-term in vitro |
| author |
Machado, Camila M. L. |
| author_facet |
Machado, Camila M. L. Ikemori, Rafael Y. Zorzeto, Tatiana Q. Nogueira, Ana C. M. A. Barbosa, Suse D. S. Savino, Wilson Schenka, André A. Vassallo, José Heinrich, Juliana K. Boetcher-Luiz, Fátima Verinaud, Liana |
| author_role |
author |
| author2 |
Ikemori, Rafael Y. Zorzeto, Tatiana Q. Nogueira, Ana C. M. A. Barbosa, Suse D. S. Savino, Wilson Schenka, André A. Vassallo, José Heinrich, Juliana K. Boetcher-Luiz, Fátima Verinaud, Liana |
| author2_role |
author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Machado, Camila M. L. Ikemori, Rafael Y. Zorzeto, Tatiana Q. Nogueira, Ana C. M. A. Barbosa, Suse D. S. Savino, Wilson Schenka, André A. Vassallo, José Heinrich, Juliana K. Boetcher-Luiz, Fátima Verinaud, Liana |
| dc.subject.other.pt_BR.fl_str_mv |
Resistência a Medicamentos Progresso tumoral Linha de células NG97 Sistema nervoso central Astrocitoma |
| topic |
Resistência a Medicamentos Progresso tumoral Linha de células NG97 Sistema nervoso central Astrocitoma tumoral progress drug resistance cultured cell lines NG97 cell line astrocytoma Central Nervous System |
| dc.subject.en.pt_BR.fl_str_mv |
tumoral progress drug resistance cultured cell lines NG97 cell line astrocytoma Central Nervous System |
| description |
Universidade Estadual de Campinas. Instituto de Biologia. Departamento de Microbiologia e Imunologia. Campinas, SP, Brasil. |
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2008 |
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2008 |
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2018-08-21T15:05:04Z |
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2018-08-21T15:05:04Z |
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info:eu-repo/semantics/article |
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MACHADO, Camila M. L. et al. Characterization of cells recovered from the xenotransplanted NG97 human-derived glioma cell line subcultured in a long-term in vitro. BMC Cancer, v.8, n.291, 13p, 2008. |
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https://www.arca.fiocruz.br/handle/icict/28273 |
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1471-2407 |
| dc.identifier.doi.none.fl_str_mv |
10.1186/1471-2407-8-291 |
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MACHADO, Camila M. L. et al. Characterization of cells recovered from the xenotransplanted NG97 human-derived glioma cell line subcultured in a long-term in vitro. BMC Cancer, v.8, n.291, 13p, 2008. 1471-2407 10.1186/1471-2407-8-291 |
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