Factors Associated with Clinical and Topographical Features of Laryngeal Tuberculosis
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2016 |
| Outros Autores: | , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/16505 |
Resumo: | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunoparasitlogia. Rio de Janeiro, RJ, Brasil / Hospital Federal de Bosucesso. Departamento de Broncoesofagolaringologia e Cirurgia de Cabeça e Pescoço. Rio de Janeiro, RJ, Brasil. |
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Reis, João Gustavo CorrêaReis, Clarissa Souza MotaCosta, Daniel César Silva daLucena, Márcia MendonçaSchubach, Armando de OliveiraOliveira, Raquel de Vasconcellos Carvalhaes deRolla, Valéria CavalcantiSilva, Fátima ConceiçãoRosalino, Cláudia Maria Valete2016-12-11T17:48:59Z2016-12-11T17:48:59Z2016REIS, João Gustavo Corrêa et al. Factors Associated with Clinical and Topographical Features of laryngeal Tuberculosis. Plos One, v. 11, n. 4, p. 1-14, Apr. 2016.1932-6203https://www.arca.fiocruz.br/handle/icict/1650510.1371/journal.pone.0153450engPublic Library of ScienceTuberculose laríngeaCaracterísticas clínicas e topográficasFatores AssociadosLaryngeal TuberculosisClinical and Topographical FeaturesFactors AssociatedFactors Associated with Clinical and Topographical Features of Laryngeal Tuberculosisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunoparasitlogia. Rio de Janeiro, RJ, Brasil / Hospital Federal de Bosucesso. Departamento de Broncoesofagolaringologia e Cirurgia de Cabeça e Pescoço. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, BrasilFundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunoparasitlogia. Rio de Janeiro, RJ, BrasilFundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasi / Universidade Federal do Rio de Janeiro. Faculdade de Medicina. Departmento de Otorrinolaringologia e Oftalmologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, BrasilFundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, BrasilFundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, BrasilFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunoparasitologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasi / Universidade Federal do Rio de Janeiro. Faculdade de Medicina. Departmento de Otorrinolaringologia e Oftalmologia. Rio de Janeiro, RJ, Brasil.Abstract INTRODUCTION: Laryngeal tuberculosis (LTB) is the most frequent granulomatous disease of the larynx and represents less than 2% of extrapulmonary TB cases. There are no pathognomonic clinical and endoscopic features of this disease and studies on LTB that can assist in its diagnostic characterization are lacking. OBJECTIVE: To identify factors associated with clinical and topographical features of LTB. METHOD: a retrospective cross-sectional study was conducted from the medical records of 36 patients with confirmed LTB diagnosis. RESULTS: Dysphonia and cough were the main symptoms presented by patients and the true vocal folds the most frequently affected site. The average of the duration of the disease evolution was significantly higher in patients with dysphonia than in patients without this symptom. We observed association between dysphonia and true vocal fold lesions and between odynophagia and lesions in the epiglottis, arytenoids and aryepiglottic folds. Odynophagia was more frequent in individuals with lesions in four or more laryngeal sites. Weight loss equal or above 10% of the body weight was more frequent in patients with odynophagia as first symptom and in patients with ulcerated lesion. Dyspnea on exertion was more frequent in individuals with more extensive laryngeal lesions. The percentage of smokers with lesions in four or more laryngeal sites was greater than that found in non-smokers. Laryngeal tissue fragment bacilloscopy and culture examinations were less positive than sputum ones. CONCLUSIONS: Smoking appears to be associated with the development of more extensive LTB lesions, and LTB with dyspnea on exertion and odynophagia with consequent impairment of nutritional status. We emphasize the need for histopathologic confirmation, once positive sputum bacteriological examinations seem not to necessarily reflect laryngeal involvement.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/16505/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALdaniel_costa_etal_IOC_2016.pdfdaniel_costa_etal_IOC_2016.pdfapplication/pdf345592https://www.arca.fiocruz.br/bitstream/icict/16505/2/daniel_costa_etal_IOC_2016.pdf379d1173e68721bd6f2e194d72b7e8b7MD52TEXTdaniel_costa_etal_IOC_2016.pdf.txtdaniel_costa_etal_IOC_2016.pdf.txtExtracted texttext/plain48915https://www.arca.fiocruz.br/bitstream/icict/16505/3/daniel_costa_etal_IOC_2016.pdf.txt3a5338d28e420c91a80a5ce8470b0479MD53icict/165052023-10-28 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| dc.title.pt_BR.fl_str_mv |
Factors Associated with Clinical and Topographical Features of Laryngeal Tuberculosis |
| title |
Factors Associated with Clinical and Topographical Features of Laryngeal Tuberculosis |
| spellingShingle |
Factors Associated with Clinical and Topographical Features of Laryngeal Tuberculosis Reis, João Gustavo Corrêa Tuberculose laríngea Características clínicas e topográficas Fatores Associados Laryngeal Tuberculosis Clinical and Topographical Features Factors Associated |
| title_short |
Factors Associated with Clinical and Topographical Features of Laryngeal Tuberculosis |
| title_full |
Factors Associated with Clinical and Topographical Features of Laryngeal Tuberculosis |
| title_fullStr |
Factors Associated with Clinical and Topographical Features of Laryngeal Tuberculosis |
| title_full_unstemmed |
Factors Associated with Clinical and Topographical Features of Laryngeal Tuberculosis |
| title_sort |
Factors Associated with Clinical and Topographical Features of Laryngeal Tuberculosis |
| author |
Reis, João Gustavo Corrêa |
| author_facet |
Reis, João Gustavo Corrêa Reis, Clarissa Souza Mota Costa, Daniel César Silva da Lucena, Márcia Mendonça Schubach, Armando de Oliveira Oliveira, Raquel de Vasconcellos Carvalhaes de Rolla, Valéria Cavalcanti Silva, Fátima Conceição Rosalino, Cláudia Maria Valete |
| author_role |
author |
| author2 |
Reis, Clarissa Souza Mota Costa, Daniel César Silva da Lucena, Márcia Mendonça Schubach, Armando de Oliveira Oliveira, Raquel de Vasconcellos Carvalhaes de Rolla, Valéria Cavalcanti Silva, Fátima Conceição Rosalino, Cláudia Maria Valete |
| author2_role |
author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Reis, João Gustavo Corrêa Reis, Clarissa Souza Mota Costa, Daniel César Silva da Lucena, Márcia Mendonça Schubach, Armando de Oliveira Oliveira, Raquel de Vasconcellos Carvalhaes de Rolla, Valéria Cavalcanti Silva, Fátima Conceição Rosalino, Cláudia Maria Valete |
| dc.subject.other.pt_BR.fl_str_mv |
Tuberculose laríngea Características clínicas e topográficas Fatores Associados |
| topic |
Tuberculose laríngea Características clínicas e topográficas Fatores Associados Laryngeal Tuberculosis Clinical and Topographical Features Factors Associated |
| dc.subject.en.pt_BR.fl_str_mv |
Laryngeal Tuberculosis Clinical and Topographical Features Factors Associated |
| description |
Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunoparasitlogia. Rio de Janeiro, RJ, Brasil / Hospital Federal de Bosucesso. Departamento de Broncoesofagolaringologia e Cirurgia de Cabeça e Pescoço. Rio de Janeiro, RJ, Brasil. |
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2016 |
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2016-12-11T17:48:59Z |
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2016-12-11T17:48:59Z |
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2016 |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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REIS, João Gustavo Corrêa et al. Factors Associated with Clinical and Topographical Features of laryngeal Tuberculosis. Plos One, v. 11, n. 4, p. 1-14, Apr. 2016. |
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https://www.arca.fiocruz.br/handle/icict/16505 |
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1932-6203 |
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10.1371/journal.pone.0153450 |
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REIS, João Gustavo Corrêa et al. Factors Associated with Clinical and Topographical Features of laryngeal Tuberculosis. Plos One, v. 11, n. 4, p. 1-14, Apr. 2016. 1932-6203 10.1371/journal.pone.0153450 |
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