Familial aggregation of cardiovascular risk factors—The Rio de Janeiro study

Detalhes bibliográficos
Autor(a) principal: Pozzan, R.
Data de Publicação: 2000
Outros Autores: Magalhães, M. E. C., Brandão, A. A., Andrade, Carla Lourenço Tavares de, Szwarcwald, Celia Landmann, Brandão, A. P.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/670
Resumo: R. Pozzan, M. E. C. Magalhães, A. A. Brandão, C. L. T. Andrade, C. L. Szwarcwald and A. P. Brandão State University of Rio de Janeiro - Rio de Janeiro - Brazil
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spelling Pozzan, R.Magalhães, M. E. C.Brandão, A. A.Andrade, Carla Lourenço Tavares deSzwarcwald, Celia LandmannBrandão, A. P.2010-08-23T16:58:37Z2010-11-04T14:19:38Z2010-08-23T16:58:37Z2010-11-04T14:19:38Z2000POZZAN, R. et al. Familial aggregation of cardiovascular risk factors: the Rio de Janeiro study. American Journal of Hypertension, v. 13, n. 4, part 2, 2000.0895-7061https://www.arca.fiocruz.br/handle/icict/670R. Pozzan, M. E. C. Magalhães, A. A. Brandão, C. L. T. Andrade, C. L. Szwarcwald and A. P. Brandão State University of Rio de Janeiro - Rio de Janeiro - BrazilDisturbance of lipid and carbohydrate metabolism, overweight, and high blood pressure seem to be strongly aggregated in families, constituting the multiple metabolic syndrome. In order to investigate these findings, 259 children and adolescents, came from a blood pressure (BP) study developed in 1987–89, were evaluated with their parents (n=414) and siblings (n=519) 10 years later. Clinical (BP, weight, sex, and age) and laboratorial (cholesterol [C], HDL cholesterol [HDL], LDL cholesterol [LDL], triglycerides [TG], and insulin [I]) data were obtained. A standardized regression analyses of the residuals (predicted value subtracted from measured value) was adapted for each lipid, anthropometric and BP variables. Sex, age, and weight were used to adjust BP correlations and sex, age, weight, and BP were used to control lipids correlations. The correlation coefficients found were expressed in the table below: These data show a strong familial aggregation of cardiovascular risk factors, specially with mothers and sons, suggesting that genetic and environmental factors play an important role in this determinism. Moreover, these findings reinforce the concept that primary prevention should begin early in life.Universidade do Estado do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.Universidade do Estado do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.Universidade do Estado do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública. Departamento de Administração e Planejamento em Saúde. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública. Departamento de Administração e Planejamento em Saúde. Rio de Janeiro, RJ, Brasil.Universidade do Estado do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.engElsevier Science IncBlood pressurerisk factorsfamilial aggregationFamilial aggregation of cardiovascular risk factors—The Rio de Janeiro studyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZTEXTLANDMANN_Familial Aggregation_2000.pdf.txtLANDMANN_Familial Aggregation_2000.pdf.txtExtracted texttext/plain11071https://www.arca.fiocruz.br/bitstream/icict/670/6/LANDMANN_Familial%20Aggregation_2000.pdf.txt410ed73aea56bc5c712f7fe0cd8b7814MD56ORIGINALLANDMANN_Familial Aggregation_2000.pdfapplication/pdf187534https://www.arca.fiocruz.br/bitstream/icict/670/2/LANDMANN_Familial%20Aggregation_2000.pdf574f4cee0411b18880fa5b0c9355eb9cMD52LICENSElicense.txttext/plain1848https://www.arca.fiocruz.br/bitstream/icict/670/3/license.txtc2574946aaa52c2a6f639b0a6cef7106MD53THUMBNAILLANDMANN_Familial Aggregation_2000.pdf.jpgLANDMANN_Familial Aggregation_2000.pdf.jpgGenerated Thumbnailimage/jpeg2367https://www.arca.fiocruz.br/bitstream/icict/670/5/LANDMANN_Familial%20Aggregation_2000.pdf.jpgb0fb1755bbd6eacea0f6d87401897c6cMD55icict/6702023-08-23 13:05:16.379oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-08-23T16:05:16Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Familial aggregation of cardiovascular risk factors—The Rio de Janeiro study
title Familial aggregation of cardiovascular risk factors—The Rio de Janeiro study
spellingShingle Familial aggregation of cardiovascular risk factors—The Rio de Janeiro study
Pozzan, R.
Blood pressure
risk factors
familial aggregation
title_short Familial aggregation of cardiovascular risk factors—The Rio de Janeiro study
title_full Familial aggregation of cardiovascular risk factors—The Rio de Janeiro study
title_fullStr Familial aggregation of cardiovascular risk factors—The Rio de Janeiro study
title_full_unstemmed Familial aggregation of cardiovascular risk factors—The Rio de Janeiro study
title_sort Familial aggregation of cardiovascular risk factors—The Rio de Janeiro study
author Pozzan, R.
author_facet Pozzan, R.
Magalhães, M. E. C.
Brandão, A. A.
Andrade, Carla Lourenço Tavares de
Szwarcwald, Celia Landmann
Brandão, A. P.
author_role author
author2 Magalhães, M. E. C.
Brandão, A. A.
Andrade, Carla Lourenço Tavares de
Szwarcwald, Celia Landmann
Brandão, A. P.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Pozzan, R.
Magalhães, M. E. C.
Brandão, A. A.
Andrade, Carla Lourenço Tavares de
Szwarcwald, Celia Landmann
Brandão, A. P.
dc.subject.por.fl_str_mv Blood pressure
risk factors
familial aggregation
topic Blood pressure
risk factors
familial aggregation
description R. Pozzan, M. E. C. Magalhães, A. A. Brandão, C. L. T. Andrade, C. L. Szwarcwald and A. P. Brandão State University of Rio de Janeiro - Rio de Janeiro - Brazil
publishDate 2000
dc.date.issued.fl_str_mv 2000
dc.date.accessioned.fl_str_mv 2010-08-23T16:58:37Z
2010-11-04T14:19:38Z
dc.date.available.fl_str_mv 2010-08-23T16:58:37Z
2010-11-04T14:19:38Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv POZZAN, R. et al. Familial aggregation of cardiovascular risk factors: the Rio de Janeiro study. American Journal of Hypertension, v. 13, n. 4, part 2, 2000.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/670
dc.identifier.issn.pt_BR.fl_str_mv 0895-7061
identifier_str_mv POZZAN, R. et al. Familial aggregation of cardiovascular risk factors: the Rio de Janeiro study. American Journal of Hypertension, v. 13, n. 4, part 2, 2000.
0895-7061
url https://www.arca.fiocruz.br/handle/icict/670
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier Science Inc
publisher.none.fl_str_mv Elsevier Science Inc
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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