Effect of triflumuron, a chitin synthesis inhibitor, on Aedes aegypti , Aedes albopictus and Culex quinquefasciatus under laboratory conditions

Detalhes bibliográficos
Autor(a) principal: Belinato, Thiago Affonso
Data de Publicação: 2013
Outros Autores: Martins, Ademir Jesus, Lima, José Bento Pereira, Valle, Denise
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/11571
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Fisiologia e Controle de Artrópodes Vetores. Rio de Janeiro, RJ, Brasil / Instituto de Biologia do Exército. Laboratório de Entomologia. Rio de Janeiro, RJ, Brasil.
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spelling Belinato, Thiago AffonsoMartins, Ademir JesusLima, José Bento PereiraValle, Denise2015-08-19T13:49:34Z2015-08-19T13:49:34Z2013BELINATO, Thiago Affonso: et al. Effect of triflumuron, a chitin synthesis inhibitor, on Aedes aegypti, Aedes albopictus and Culex quinquefasciatus under laboratory conditions. Parasites & Vectors , v.6, n.83, 7p, Apr. 2013.https://www.arca.fiocruz.br/handle/icict/1157110.1186/1756-3305-6-83engBioMed CentralEffect of triflumuron, a chitin synthesis inhibitor, on Aedes aegypti , Aedes albopictus and Culex quinquefasciatus under laboratory conditionsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Fisiologia e Controle de Artrópodes Vetores. Rio de Janeiro, RJ, Brasil / Instituto de Biologia do Exército. Laboratório de Entomologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Fisiologia e Controle de Artrópodes Vetores. Rio de Janeiro, RJ, Brasil / Instituto de Biologia do Exército. Laboratório de Entomologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Fisiologia e Controle de Artrópodes Vetores. Rio de Janeiro, RJ, Brasil / Instituto de Biologia do Exército. Laboratório de Entomologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Fisiologia e Controle de Artrópodes Vetores. Rio de Janeiro, RJ, Brasil / Instituto de Biologia do Exército. Laboratório de Entomologia. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Instituto de Bioquímica Médica. Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular. Rio de Janeiro, RJ, Brasil.Resistance to traditional insecticides represents a threat to the control of disease vectors. The insect growth regulators (IGR) are a potential alternative to control mosquitoes, including resistant populations. The chitin synthesis inhibitors (CSI) are IGRs, which interfere with the insect molting process and represent one major class of compounds against Aedes aegypti populations resistant to the larvicide organophosphate temephos. In the present study, we evaluated the efficacy of the CSI triflumuron on Culex quinquefasciatus, Aedes albopictus and against several Ae. aegypti field populations. METHODS: The efficacy of triflumuron, against Cx. quinquefasciatus and Ae. albopictus was evaluated with laboratory strains through dose-response assays. Additionaly, this CSI was tested against seven Ae. aegypti field populations exhibiting distinct resistance levels to both temephos and the pyrethroid deltamethrin. Aedes aegypti populations were exposed to both a dose that inhibits 99% of the adult emergence of mosquitoes from the susceptible reference strain, Rockefeller, (EI₉₉ = 3.95 μg/L) and the diagnostic dose (DD), corresponding to twice the EI₉₉. RESULTS: Our results indicate that triflumuron was effective in emergence inhibition (EI) of Cx. quinquefasciatus (EI₅₀ = 5.28 μg/L; EI₉₀= 12.47 μg/L) and Ae. albopictus (EI₅₀ = 1.59 μg/L; EI₉₀= 2.63 μg/L). Triflumuron was also effective against seven Ae. aegypti Brazilian populations resistant to both temephos and deltamethrin. Exposure of all the Ae. aegypti populations to the triflumuron EI₉₉ of the susceptible reference strain, Rockefeller, resulted in complete inhibition of adult emergence, suggesting no cross-resistance among traditional insecticides and this CSI. However, a positive correlation between temephos resistance and tolerance to triflumuron was observed. CONCLUSION: The results suggest that triflumuron represents a potential tool for the control of disease vectors in public health. Nevertheless, they point to the need of constant monitoring of the susceptibility status of vector populations to CSIs.Aedes aegyptiAedes albopictusCulex quinquefasciatusResistência a InseticidasChitin synthesis inhibitorsInsecticide resistanceAedesResistência a Inseticidasinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1914https://www.arca.fiocruz.br/bitstream/icict/11571/1/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD51ORIGINALdenise_valle_etal_IOC_2103.pdfapplication/pdf553516https://www.arca.fiocruz.br/bitstream/icict/11571/2/denise_valle_etal_IOC_2103.pdf19ef929256cd066662923695418a54a1MD52TEXTdenise_valle_etal_IOC_2103.pdf.txtdenise_valle_etal_IOC_2103.pdf.txtExtracted texttext/plain34490https://www.arca.fiocruz.br/bitstream/icict/11571/3/denise_valle_etal_IOC_2103.pdf.txtba9c8e2e81af515a1a3974db2892298bMD53icict/115712022-06-24 12:17:38.636oai:www.arca.fiocruz.br:icict/11571TElDRU7Dh0EgREUgRElTVFJJQlVJw4fDg08gTsODTy1FWENMVVNJVkEKCkFvIGNvbmNvcmRhciBlIGFjZWl0YXIgZXN0YSBsaWNlbsOnYSB2b2PDqiAoYXV0b3Igb3UgZGV0ZW50b3IgZG9zIGRpcmVpdG9zIGF1dG9yYWlzKToKCmEpIERlY2xhcmEgcXVlIGNvbmhlY2UgYSBwb2zDrXRpY2EgZGUgY29weXJpZ2h0IGRhIGVkaXRvcmEgZG8gc2V1IGRvY3VtZW50by4KCmIpIERlY2xhcmEgcXVlIGNvbmhlY2UgZSBhY2VpdGEgYXMgRGlyZXRyaXplcyBwYXJhIG8gUmVwb3NpdMOzcmlvIEluc3RpdHVjaW9uYWwgZGEgRnVuZGHDp8OjbyBPc3dhbGRvIENydXogKEZJT0NSVVopLgoKYykgQ29uY2VkZSDDoCBGSU9DUlVaIG8gZGlyZWl0byBuw6NvLWV4Y2x1c2l2byBkZSBhcnF1aXZhciwgcmVwcm9kdXppciwgY29udmVydGVyIChjb21vIGRlZmluaWRvIGEgc2VndWlyKSwgY29tdW5pY2FyCiAKZS9vdSBkaXN0cmlidWlyIG5vIFJlcG9zaXTDs3JpbyBkYSBGSU9DUlVaLCBvIGRvY3VtZW50byBlbnRyZWd1ZSAoaW5jbHVpbmRvIG8gcmVzdW1vL2Fic3RyYWN0KSBlbSBmb3JtYXRvIGRpZ2l0YWwgb3UgCgpwb3IgcXVhbHF1ZXIgb3V0cm8gbWVpby4KCmQpIERlY2xhcmEgcXVlIGF1dG9yaXphIGEgRklPQ1JVWiBhIGFycXVpdmFyIG1haXMgZGUgdW1hIGPDs3BpYSBkZXN0ZSBkb2N1bWVudG8gZSBjb252ZXJ0w6otbG8sIHNlbSBhbHRlcmFyIG8gc2V1IGNvbnRlw7pkbywgCgpwYXJhIHF1YWxxdWVyIGZvcm1hdG8gZGUgYXJxdWl2bywgbWVpbyBvdSBzdXBvcnRlLCBwYXJhIGVmZWl0b3MgZGUgc2VndXJhbsOnYSwgcHJlc2VydmHDp8OjbyAoYmFja3VwKSBlIGFjZXNzby4KCmUpIERlY2xhcmEgcXVlIG8gZG9jdW1lbnRvIHN1Ym1ldGlkbyDDqSBvIHNldSB0cmFiYWxobyBvcmlnaW5hbCwgZSBxdWUgZGV0w6ltIG8gZGlyZWl0byBkZSBjb25jZWRlciBhIHRlcmNlaXJvcyBvcyBkaXJlaXRvcyAKCmNvbnRpZG9zIG5lc3RhIGxpY2Vuw6dhLiBEZWNsYXJhIHRhbWLDqW0gcXVlIGEgZW50cmVnYSBkbyBkb2N1bWVudG8gbsOjbyBpbmZyaW5nZSBvcyBkaXJlaXRvcyBkZSBxdWFscXVlciBvdXRyYSBwZXNzb2Egb3UgZW50aWRhZGUuCgpmKSBEZWNsYXJhIHF1ZSwgbm8gY2FzbyBkbyBkb2N1bWVudG8gc3VibWV0aWRvIGNvbnRlciBtYXRlcmlhbCBkbyBxdWFsIG7Do28gZGV0w6ltIG9zIGRpcmVpdG9zIGRlIGF1dG9yLCBvYnRldmUgYSBhdXRvcml6YcOnw6NvIAoKaXJyZXN0cml0YSBkbyByZXNwZWN0aXZvIGRldGVudG9yIGRlc3NlcyBkaXJlaXRvcywgcGFyYSBjZWRlciBhIEZJT0NSVVogb3MgZGlyZWl0b3MgcmVxdWVyaWRvcyBwb3IgZXN0YSBMaWNlbsOnYSBlIGF1dG9yaXphciBhIAoKdXRpbGl6w6EtbG9zIGxlZ2FsbWVudGUuIERlY2xhcmEgdGFtYsOpbSBxdWUgZXNzZSBtYXRlcmlhbCBjdWpvcyBkaXJlaXRvcyBzw6NvIGRlIHRlcmNlaXJvcyBlc3TDoSBjbGFyYW1lbnRlIGlkZW50aWZpY2FkbyBlIHJlY29uaGVjaWRvIAoKbm8gdGV4dG8gb3UgY29udGXDumRvIGRvIGRvY3VtZW50byBlbnRyZWd1ZS4KCmcpIFNFIE8gRE9DVU1FTlRPIEVOVFJFR1VFIMOJIEJBU0VBRE8gRU0gVFJBQkFMSE8gRklOQU5DSUFETyBPVSBBUE9JQURPIFBPUiBPVVRSQSBJTlNUSVRVScOHw4NPIFFVRSBOw4NPIEEgRklPQ1JVWiwgREVDTEFSQSBRVUUgQ1VNUFJJVSAKClFVQUlTUVVFUiBPQlJJR0HDh8OVRVMgRVhJR0lEQVMgUEVMTyBSRVNQRUNUSVZPIENPTlRSQVRPIE9VIEFDT1JETy4gQSBGSU9DUlVaIGlkZW50aWZpY2Fyw6EgY2xhcmFtZW50ZSBvKHMpIG5vbWUocykgZG8ocykgYXV0b3IoZXMpIGRvcyAKCmRpcmVpdG9zIGRvIGRvY3VtZW50byBlbnRyZWd1ZSBlIG7Do28gZmFyw6EgcXVhbHF1ZXIgYWx0ZXJhw6fDo28sIHBhcmEgYWzDqW0gZG8gcHJldmlzdG8gbmEgYWzDrW5lYSBjKS4KRepositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-06-24T15:17:38Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Effect of triflumuron, a chitin synthesis inhibitor, on Aedes aegypti , Aedes albopictus and Culex quinquefasciatus under laboratory conditions
title Effect of triflumuron, a chitin synthesis inhibitor, on Aedes aegypti , Aedes albopictus and Culex quinquefasciatus under laboratory conditions
spellingShingle Effect of triflumuron, a chitin synthesis inhibitor, on Aedes aegypti , Aedes albopictus and Culex quinquefasciatus under laboratory conditions
Belinato, Thiago Affonso
Aedes aegypti
Aedes albopictus
Culex quinquefasciatus
Resistência a Inseticidas
Chitin synthesis inhibitors
Insecticide resistance
Aedes
Resistência a Inseticidas
title_short Effect of triflumuron, a chitin synthesis inhibitor, on Aedes aegypti , Aedes albopictus and Culex quinquefasciatus under laboratory conditions
title_full Effect of triflumuron, a chitin synthesis inhibitor, on Aedes aegypti , Aedes albopictus and Culex quinquefasciatus under laboratory conditions
title_fullStr Effect of triflumuron, a chitin synthesis inhibitor, on Aedes aegypti , Aedes albopictus and Culex quinquefasciatus under laboratory conditions
title_full_unstemmed Effect of triflumuron, a chitin synthesis inhibitor, on Aedes aegypti , Aedes albopictus and Culex quinquefasciatus under laboratory conditions
title_sort Effect of triflumuron, a chitin synthesis inhibitor, on Aedes aegypti , Aedes albopictus and Culex quinquefasciatus under laboratory conditions
author Belinato, Thiago Affonso
author_facet Belinato, Thiago Affonso
Martins, Ademir Jesus
Lima, José Bento Pereira
Valle, Denise
author_role author
author2 Martins, Ademir Jesus
Lima, José Bento Pereira
Valle, Denise
author2_role author
author
author
dc.contributor.author.fl_str_mv Belinato, Thiago Affonso
Martins, Ademir Jesus
Lima, José Bento Pereira
Valle, Denise
dc.subject.en.pt_BR.fl_str_mv Aedes aegypti
Aedes albopictus
Culex quinquefasciatus
Resistência a Inseticidas
Chitin synthesis inhibitors
Insecticide resistance
topic Aedes aegypti
Aedes albopictus
Culex quinquefasciatus
Resistência a Inseticidas
Chitin synthesis inhibitors
Insecticide resistance
Aedes
Resistência a Inseticidas
dc.subject.decs.pt_BR.fl_str_mv Aedes
Resistência a Inseticidas
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Fisiologia e Controle de Artrópodes Vetores. Rio de Janeiro, RJ, Brasil / Instituto de Biologia do Exército. Laboratório de Entomologia. Rio de Janeiro, RJ, Brasil.
publishDate 2013
dc.date.issued.fl_str_mv 2013
dc.date.accessioned.fl_str_mv 2015-08-19T13:49:34Z
dc.date.available.fl_str_mv 2015-08-19T13:49:34Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv BELINATO, Thiago Affonso: et al. Effect of triflumuron, a chitin synthesis inhibitor, on Aedes aegypti, Aedes albopictus and Culex quinquefasciatus under laboratory conditions. Parasites & Vectors , v.6, n.83, 7p, Apr. 2013.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/11571
dc.identifier.doi.pt_BR.fl_str_mv 10.1186/1756-3305-6-83
identifier_str_mv BELINATO, Thiago Affonso: et al. Effect of triflumuron, a chitin synthesis inhibitor, on Aedes aegypti, Aedes albopictus and Culex quinquefasciatus under laboratory conditions. Parasites & Vectors , v.6, n.83, 7p, Apr. 2013.
10.1186/1756-3305-6-83
url https://www.arca.fiocruz.br/handle/icict/11571
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
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instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
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reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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