Factors associated with high levels of glycated haemoglobin in patients with type 1 diabetes: a multicentre study in Brazil

Detalhes bibliográficos
Autor(a) principal: Andrade, Carine de Sousa
Data de Publicação: 2017
Outros Autores: Ribeiro, Guilherme de Sousa, Santos, Carlos Antonio Souza Teles, Neves, Raimundo Celestino Silva, Moreira Junior, Edson Duarte
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/24876
Resumo: The Brazilian Study of Diabetes Control was funded by Pfizer, Brazil. CSA received scholarship from the Coordination for the Improvement of Higher Education Personnel (CAPES), Brazilian Ministry of Education. GSR and EDM received scholarships from the National Council for Scientific and Technological Development (CNPq).
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spelling Andrade, Carine de SousaRibeiro, Guilherme de SousaSantos, Carlos Antonio Souza TelesNeves, Raimundo Celestino SilvaMoreira Junior, Edson Duarte2018-02-20T12:54:05Z2018-02-20T12:54:05Z2017ANDRADE, C. S. et al. Factors associated with high levels of glycated haemoglobin in patients with type 1 diabetes: a multicentre study in Brazil. BMJ Open, v. 7, e018094, 2017.2044-6055https://www.arca.fiocruz.br/handle/icict/2487610.1136/bmjopen-2017-018094The Brazilian Study of Diabetes Control was funded by Pfizer, Brazil. CSA received scholarship from the Coordination for the Improvement of Higher Education Personnel (CAPES), Brazilian Ministry of Education. GSR and EDM received scholarships from the National Council for Scientific and Technological Development (CNPq).Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Escola de Nutrição. Salvador, BA, BrasilFundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, BrasilFundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / State University of Feira de Santana. Department of Exact Sciences. Feira de Santana, BA, BrazilFundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Charitable Works Foundation of Sister Dulce. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, BrasilLong-term complications of type 1 diabetes mellitus (DM1) can be prevented with adequate glycaemic control. However, high levels of glycated haemoglobin (HbA1c) occur in 60%-90% of the patients with DM1. Thus, we aimed to investigate the role of sociodemographic, behavioural and clinical factors on the HbA1c levels of patients with DM1 in Brazil. Design, setting and participants A cross-sectional study was conducted in ambulatory patients with DM1 aged ≥18 years from 10 Brazilian cities. Sociodemographic, behavioural and clinical data were obtained through interviews. Main outcome measures HbA1c level was measured by liquid chromatography. Hierarchical multiple variable linear regression models were used to identify factors correlated with high levels of HbA1c. Results Of 979 patients with DM1, 63.8% were women, and the mean age was 40 (SD 14.6) years. The mean HbA1c level was 9.4% (SD 2.2%), and 89.6% of the patients had HbA1c ≥7.0%. Factors independently correlated with increased HbA1c levels included: lower education, non-participation in diabetes classes/lecture during the year before, having a self-perception of poor adherence to diet and insulin, not having private medical care and not measuring the HbA1c levels in the prior year. Of note, poor adherence to diet and insulin were the independent factors most strongly associated with high levels of HbA1c (mean increment in HbA1c levels of 0.88% and 1.25%, respectively). Conclusion Poor glycaemic control, which is common among Brazilian patients with DM1, is associated with lower education, self-perception of insufficient adherence to diet and insulin and inadequate monitoring of HbA1c levels. Specific actions, particularly those targeting improving adherence to diet and insulin, may contribute to successful management of patients with DM1.engBMJ Publishing GroupControle glicêmicoEpidemiologiaHemoglobina glicadaDiabetes tipo 1Glycaemic controlEpidemiologyGlycated HaemoglobinType 1 diabetesFactors associated with high levels of glycated haemoglobin in patients with type 1 diabetes: a multicentre study in Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/24876/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALAndrade CS Factors associated with high levels....pdfAndrade CS Factors associated with high 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dc.title.pt_BR.fl_str_mv Factors associated with high levels of glycated haemoglobin in patients with type 1 diabetes: a multicentre study in Brazil
title Factors associated with high levels of glycated haemoglobin in patients with type 1 diabetes: a multicentre study in Brazil
spellingShingle Factors associated with high levels of glycated haemoglobin in patients with type 1 diabetes: a multicentre study in Brazil
Andrade, Carine de Sousa
Controle glicêmico
Epidemiologia
Hemoglobina glicada
Diabetes tipo 1
Glycaemic control
Epidemiology
Glycated Haemoglobin
Type 1 diabetes
title_short Factors associated with high levels of glycated haemoglobin in patients with type 1 diabetes: a multicentre study in Brazil
title_full Factors associated with high levels of glycated haemoglobin in patients with type 1 diabetes: a multicentre study in Brazil
title_fullStr Factors associated with high levels of glycated haemoglobin in patients with type 1 diabetes: a multicentre study in Brazil
title_full_unstemmed Factors associated with high levels of glycated haemoglobin in patients with type 1 diabetes: a multicentre study in Brazil
title_sort Factors associated with high levels of glycated haemoglobin in patients with type 1 diabetes: a multicentre study in Brazil
author Andrade, Carine de Sousa
author_facet Andrade, Carine de Sousa
Ribeiro, Guilherme de Sousa
Santos, Carlos Antonio Souza Teles
Neves, Raimundo Celestino Silva
Moreira Junior, Edson Duarte
author_role author
author2 Ribeiro, Guilherme de Sousa
Santos, Carlos Antonio Souza Teles
Neves, Raimundo Celestino Silva
Moreira Junior, Edson Duarte
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Andrade, Carine de Sousa
Ribeiro, Guilherme de Sousa
Santos, Carlos Antonio Souza Teles
Neves, Raimundo Celestino Silva
Moreira Junior, Edson Duarte
dc.subject.other.pt_BR.fl_str_mv Controle glicêmico
Epidemiologia
Hemoglobina glicada
Diabetes tipo 1
topic Controle glicêmico
Epidemiologia
Hemoglobina glicada
Diabetes tipo 1
Glycaemic control
Epidemiology
Glycated Haemoglobin
Type 1 diabetes
dc.subject.en.pt_BR.fl_str_mv Glycaemic control
Epidemiology
Glycated Haemoglobin
Type 1 diabetes
description The Brazilian Study of Diabetes Control was funded by Pfizer, Brazil. CSA received scholarship from the Coordination for the Improvement of Higher Education Personnel (CAPES), Brazilian Ministry of Education. GSR and EDM received scholarships from the National Council for Scientific and Technological Development (CNPq).
publishDate 2017
dc.date.issued.fl_str_mv 2017
dc.date.accessioned.fl_str_mv 2018-02-20T12:54:05Z
dc.date.available.fl_str_mv 2018-02-20T12:54:05Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv ANDRADE, C. S. et al. Factors associated with high levels of glycated haemoglobin in patients with type 1 diabetes: a multicentre study in Brazil. BMJ Open, v. 7, e018094, 2017.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/24876
dc.identifier.issn.pt_BR.fl_str_mv 2044-6055
dc.identifier.doi.none.fl_str_mv 10.1136/bmjopen-2017-018094
identifier_str_mv ANDRADE, C. S. et al. Factors associated with high levels of glycated haemoglobin in patients with type 1 diabetes: a multicentre study in Brazil. BMJ Open, v. 7, e018094, 2017.
2044-6055
10.1136/bmjopen-2017-018094
url https://www.arca.fiocruz.br/handle/icict/24876
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv BMJ Publishing Group
publisher.none.fl_str_mv BMJ Publishing Group
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
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