A Conservative Region Of The Mercuric Reductase Gene (Mera) As A Molecular Marker Of Bacterial Mercury Resistance
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2008 |
| Outros Autores: | , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/1935 |
Resumo: | The authors are grateful to Centro de Pesquisa Leônidas e Maria Deane (CPqLMD) – FIOCRUZ for providing the infrastructure for this project. |
| id |
CRUZ_6ce7f89a3b9bbf21d9f4520347e83caf |
|---|---|
| oai_identifier_str |
oai:www.arca.fiocruz.br:icict/1935 |
| network_acronym_str |
CRUZ |
| network_name_str |
Repositório Institucional da FIOCRUZ (ARCA) |
| repository_id_str |
2135 |
| spelling |
Sotero-Martins, AdrianaJesus, Michele Silva deLacerda, MicheleMoreira, Josino CostaFilgueiras, Ana Luzia LauriaBarrocas, Paulo Rubens Guimarães2011-04-22T18:56:59Z2011-04-22T18:56:59Z2008SOTERO-MARTINS, Adriana et al. A conservative region of the mercuric reductase gene (merA) as a molecular marker of bacterial mercury resistance. Brazilian Journal of Microbiology, São Paulo, v. 39, n. 2, p. 307-310, June 2008.1517-8382https://www.arca.fiocruz.br/handle/icict/193510.1590/S1517-83822008000200020The authors are grateful to Centro de Pesquisa Leônidas e Maria Deane (CPqLMD) – FIOCRUZ for providing the infrastructure for this project.O mecanismo de resistência bacteriana ao mercúrio mais comum é baseada na redução do Hg(II) a Hg0, através da atividade da enzima mercúrio redutase (MerA). O uso do fragmento de 431 pb amplificado de uma região conservada do gene merA, que codifica a enzima MerA, foi utilizado como marcador molecular deste mecanismo, permitindo a identificação de bactérias resistentes ao mercúrioThe most common bacterial mercury resistance mechanism is based on the reduction of Hg(II) to Hg0, which is dependent of the mercuric reductase enzyme (MerA) activity. The use of a 431 bp fragment of a conservative region of the mercuric reductase (merA) gene was applied as a molecular marker of this mechanism, allowing the identification of mercury resistant bacterial strains.This research was funded by PAPES-FIOCRUZ Program, grant 400173/2006-9, and to Conselho Nacional de Pesquisa (CNPq).Fundação Oswaldo Cruz. Centro de Pesquisa Leônidas e Maria Deane. Manaus, AM, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisa Leônidas e Maria Deane. Manaus, AM, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisa Leônidas e Maria Deane. Manaus, AM, Brasil.Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sérgio Arouca. Centro de Estudos de Saúde do Trabalhador e Ecologia Humana. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Bacteriologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sérgio Arouca. Departamento de Saneamento e Saúde Ambiental. Rio de Janeiro, RJ, Brasil.engSociedade Brasileira de MicrobiologiamerA geneMercury resistantBacteriaMolecular markerMicrobiologiaGene merAResistência ao mercúrioBactériaMarcador molecularA Conservative Region Of The Mercuric Reductase Gene (Mera) As A Molecular Marker Of Bacterial Mercury ResistanceRegião Conservada do Gene da Mercúrio Redutase (merA) como Marcador Molecular da Resistência Bacteriana ao Mercúrioinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALanaluzia_filgueiras_etal_IOC_2008.pdfanaluzia_filgueiras_etal_IOC_2008.pdfapplication/pdf4502196https://www.arca.fiocruz.br/bitstream/icict/1935/1/analuzia_filgueiras_etal_IOC_2008.pdfacdc24544cf09bc7a9f5ce783475d75dMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81648https://www.arca.fiocruz.br/bitstream/icict/1935/2/license.txte095249ac7cacefbfe39684dfe45e706MD52TEXTanaluzia_filgueiras_etal_IOC_200.pdf.txtanaluzia_filgueiras_etal_IOC_200.pdf.txtExtracted texttext/plain17363https://www.arca.fiocruz.br/bitstream/icict/1935/5/analuzia_filgueiras_etal_IOC_200.pdf.txt2a5f795d4081dbf1f972b95866e3fabbMD55analuzia_filgueiras_etal_IOC_2008.pdf.txtanaluzia_filgueiras_etal_IOC_2008.pdf.txtExtracted texttext/plain17363https://www.arca.fiocruz.br/bitstream/icict/1935/6/analuzia_filgueiras_etal_IOC_2008.pdf.txt2a5f795d4081dbf1f972b95866e3fabbMD56THUMBNAILanaluzia_filgueiras_etal_IOC_2008.pdf.jpganaluzia_filgueiras_etal_IOC_2008.pdf.jpgGenerated Thumbnailimage/jpeg2043https://www.arca.fiocruz.br/bitstream/icict/1935/4/analuzia_filgueiras_etal_IOC_2008.pdf.jpg8f76dd7c98e226b7bc651f750561b0ceMD54icict/19352023-09-05 10:07:28.396oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-09-05T13:07:28Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
| dc.title.pt_BR.fl_str_mv |
A Conservative Region Of The Mercuric Reductase Gene (Mera) As A Molecular Marker Of Bacterial Mercury Resistance |
| dc.title.alternative.none.fl_str_mv |
Região Conservada do Gene da Mercúrio Redutase (merA) como Marcador Molecular da Resistência Bacteriana ao Mercúrio |
| title |
A Conservative Region Of The Mercuric Reductase Gene (Mera) As A Molecular Marker Of Bacterial Mercury Resistance |
| spellingShingle |
A Conservative Region Of The Mercuric Reductase Gene (Mera) As A Molecular Marker Of Bacterial Mercury Resistance Sotero-Martins, Adriana Gene merA Resistência ao mercúrio Bactéria Marcador molecular merA gene Mercury resistant Bacteria Molecular marker Microbiologia |
| title_short |
A Conservative Region Of The Mercuric Reductase Gene (Mera) As A Molecular Marker Of Bacterial Mercury Resistance |
| title_full |
A Conservative Region Of The Mercuric Reductase Gene (Mera) As A Molecular Marker Of Bacterial Mercury Resistance |
| title_fullStr |
A Conservative Region Of The Mercuric Reductase Gene (Mera) As A Molecular Marker Of Bacterial Mercury Resistance |
| title_full_unstemmed |
A Conservative Region Of The Mercuric Reductase Gene (Mera) As A Molecular Marker Of Bacterial Mercury Resistance |
| title_sort |
A Conservative Region Of The Mercuric Reductase Gene (Mera) As A Molecular Marker Of Bacterial Mercury Resistance |
| author |
Sotero-Martins, Adriana |
| author_facet |
Sotero-Martins, Adriana Jesus, Michele Silva de Lacerda, Michele Moreira, Josino Costa Filgueiras, Ana Luzia Lauria Barrocas, Paulo Rubens Guimarães |
| author_role |
author |
| author2 |
Jesus, Michele Silva de Lacerda, Michele Moreira, Josino Costa Filgueiras, Ana Luzia Lauria Barrocas, Paulo Rubens Guimarães |
| author2_role |
author author author author author |
| dc.contributor.author.fl_str_mv |
Sotero-Martins, Adriana Jesus, Michele Silva de Lacerda, Michele Moreira, Josino Costa Filgueiras, Ana Luzia Lauria Barrocas, Paulo Rubens Guimarães |
| dc.subject.por.fl_str_mv |
Gene merA Resistência ao mercúrio Bactéria Marcador molecular |
| topic |
Gene merA Resistência ao mercúrio Bactéria Marcador molecular merA gene Mercury resistant Bacteria Molecular marker Microbiologia |
| dc.subject.en.pt_BR.fl_str_mv |
merA gene Mercury resistant Bacteria Molecular marker |
| dc.subject.decs.none.fl_str_mv |
Microbiologia |
| description |
The authors are grateful to Centro de Pesquisa Leônidas e Maria Deane (CPqLMD) – FIOCRUZ for providing the infrastructure for this project. |
| publishDate |
2008 |
| dc.date.issued.fl_str_mv |
2008 |
| dc.date.accessioned.fl_str_mv |
2011-04-22T18:56:59Z |
| dc.date.available.fl_str_mv |
2011-04-22T18:56:59Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.citation.fl_str_mv |
SOTERO-MARTINS, Adriana et al. A conservative region of the mercuric reductase gene (merA) as a molecular marker of bacterial mercury resistance. Brazilian Journal of Microbiology, São Paulo, v. 39, n. 2, p. 307-310, June 2008. |
| dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/1935 |
| dc.identifier.issn.pt_BR.fl_str_mv |
1517-8382 |
| dc.identifier.doi.pt_BR.fl_str_mv |
10.1590/S1517-83822008000200020 |
| identifier_str_mv |
SOTERO-MARTINS, Adriana et al. A conservative region of the mercuric reductase gene (merA) as a molecular marker of bacterial mercury resistance. Brazilian Journal of Microbiology, São Paulo, v. 39, n. 2, p. 307-310, June 2008. 1517-8382 10.1590/S1517-83822008000200020 |
| url |
https://www.arca.fiocruz.br/handle/icict/1935 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Microbiologia |
| publisher.none.fl_str_mv |
Sociedade Brasileira de Microbiologia |
| dc.source.none.fl_str_mv |
reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
| instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
| instacron_str |
FIOCRUZ |
| institution |
FIOCRUZ |
| reponame_str |
Repositório Institucional da FIOCRUZ (ARCA) |
| collection |
Repositório Institucional da FIOCRUZ (ARCA) |
| bitstream.url.fl_str_mv |
https://www.arca.fiocruz.br/bitstream/icict/1935/1/analuzia_filgueiras_etal_IOC_2008.pdf https://www.arca.fiocruz.br/bitstream/icict/1935/2/license.txt https://www.arca.fiocruz.br/bitstream/icict/1935/5/analuzia_filgueiras_etal_IOC_200.pdf.txt https://www.arca.fiocruz.br/bitstream/icict/1935/6/analuzia_filgueiras_etal_IOC_2008.pdf.txt https://www.arca.fiocruz.br/bitstream/icict/1935/4/analuzia_filgueiras_etal_IOC_2008.pdf.jpg |
| bitstream.checksum.fl_str_mv |
acdc24544cf09bc7a9f5ce783475d75d e095249ac7cacefbfe39684dfe45e706 2a5f795d4081dbf1f972b95866e3fabb 2a5f795d4081dbf1f972b95866e3fabb 8f76dd7c98e226b7bc651f750561b0ce |
| bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 MD5 |
| repository.name.fl_str_mv |
Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ) |
| repository.mail.fl_str_mv |
repositorio.arca@fiocruz.br |
| _version_ |
1813009120677068800 |