Staphylococcus epidermidis role in the skin microenvironment

Detalhes bibliográficos
Autor(a) principal: Leonel, Caroline
Data de Publicação: 2019
Outros Autores: Sena, Isadora F. G., Silva, Walison N., Prazeres, Pedro H. D. M., Fernandes, Gabriel da Rocha, Agresti, Pamela Mancha, Mintz, Akiva, Azevedo, Vasco A. C., Birbrair, Alexander
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/35061
Resumo: Universidade Federal de Minas Gerais. Departamento de Patologia. Belo Horizonte, MG, Brasil.
id CRUZ_6fbd06c14c792a166c2f5a8784ad9bc0
oai_identifier_str oai:www.arca.fiocruz.br:icict/35061
network_acronym_str CRUZ
network_name_str Repositório Institucional da FIOCRUZ (ARCA)
repository_id_str 2135
spelling Leonel, CarolineSena, Isadora F. G.Silva, Walison N.Prazeres, Pedro H. D. M.Fernandes, Gabriel da RochaAgresti, Pamela ManchaMintz, AkivaAzevedo, Vasco A. C.Birbrair, Alexander2019-08-26T13:24:43Z2019-08-26T13:24:43Z2019LEONEL, Caroline et al. Staphylococcus epidermidis role in the skin microenvironment. Journal of Cellular and Molecular Medicine, p. 1-7, 2019.1582-1838https://www.arca.fiocruz.br/handle/icict/3506110.1111/jcmm.14415engJohn Wiley & SonsStaphylococcus epidermidis role in the skin microenvironmentinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal de Minas Gerais. Departamento de Patologia. Belo Horizonte, MG, Brasil.Universidade Federal de Minas Gerais. Departamento de Patologia. Belo Horizonte, MG, Brasil.Universidade Federal de Minas Gerais. Departamento de Patologia. Belo Horizonte, MG, Brasil.Universidade Federal de Minas Gerais. Departamento de Patologia. Belo Horizonte, MG, Brasil.Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, Brasil.Universidade Federal de Minas Gerais. Departamento de Biologia Geral. Belo Horizonte, MG, Brasil.Department of Radiology, Columbia University Medical Center, New York, USA.Universidade Federal de Minas Gerais. Departamento de Biologia Geral. Belo Horizonte, MG, Brasil.Universidade Federal de Minas Gerais. Departamento de Patologia. Belo Horizonte, MG, Brasil / Department of Radiology, Columbia University Medical Center, New York, USA.Wound healing is a complex dynamic physiological process in response to cutaneous destructive stimuli that aims to restore the cutaneous' barrier role. Deciphering the underlying mechanistic details that contribute to wound healing will create novel therapeutic strategies for skin repair. Recently, by using state-of-the-art technologies, it was revealed that the cutaneous microbiota interact with skin immune cells. Strikingly, commensal Staphylococcus epidermidis-induced CD8+ T cells induce re-epithelization of the skin after injury, accelerating wound closure. From a drug development perspective, the microbiota may provide new therapeutic candidate molecules to accelerate skin healing. Here, we summarize and evaluate recent advances in the understanding of the microbiota in the skin microenvironment.MicrobiotaMicroenvironmentSkinWound healinginfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83082https://www.arca.fiocruz.br/bitstream/icict/35061/1/license.txt9193a7c197bc67acd023525e72a03240MD51ORIGINALStaphylococcus epidermidis role in the skin microenvironment.pdfStaphylococcus epidermidis role in the skin microenvironment.pdfapplication/pdf3895746https://www.arca.fiocruz.br/bitstream/icict/35061/2/Staphylococcus%20epidermidis%20role%20in%20the%20skin%20microenvironment.pdfa4a967ac59d2f92e0b7126436646ed19MD52TEXTStaphylococcus epidermidis role in the skin microenvironment.pdf.txtStaphylococcus epidermidis role in the skin microenvironment.pdf.txtExtracted texttext/plain7https://www.arca.fiocruz.br/bitstream/icict/35061/3/Staphylococcus%20epidermidis%20role%20in%20the%20skin%20microenvironment.pdf.txt212b0306580d4f0044d18f9a3edcc832MD53icict/350612019-08-27 21:05:49.045oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352019-08-28T00:05:49Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Staphylococcus epidermidis role in the skin microenvironment
title Staphylococcus epidermidis role in the skin microenvironment
spellingShingle Staphylococcus epidermidis role in the skin microenvironment
Leonel, Caroline
Microbiota
Microenvironment
Skin
Wound healing
title_short Staphylococcus epidermidis role in the skin microenvironment
title_full Staphylococcus epidermidis role in the skin microenvironment
title_fullStr Staphylococcus epidermidis role in the skin microenvironment
title_full_unstemmed Staphylococcus epidermidis role in the skin microenvironment
title_sort Staphylococcus epidermidis role in the skin microenvironment
author Leonel, Caroline
author_facet Leonel, Caroline
Sena, Isadora F. G.
Silva, Walison N.
Prazeres, Pedro H. D. M.
Fernandes, Gabriel da Rocha
Agresti, Pamela Mancha
Mintz, Akiva
Azevedo, Vasco A. C.
Birbrair, Alexander
author_role author
author2 Sena, Isadora F. G.
Silva, Walison N.
Prazeres, Pedro H. D. M.
Fernandes, Gabriel da Rocha
Agresti, Pamela Mancha
Mintz, Akiva
Azevedo, Vasco A. C.
Birbrair, Alexander
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Leonel, Caroline
Sena, Isadora F. G.
Silva, Walison N.
Prazeres, Pedro H. D. M.
Fernandes, Gabriel da Rocha
Agresti, Pamela Mancha
Mintz, Akiva
Azevedo, Vasco A. C.
Birbrair, Alexander
dc.subject.en.pt_BR.fl_str_mv Microbiota
Microenvironment
Skin
Wound healing
topic Microbiota
Microenvironment
Skin
Wound healing
description Universidade Federal de Minas Gerais. Departamento de Patologia. Belo Horizonte, MG, Brasil.
publishDate 2019
dc.date.accessioned.fl_str_mv 2019-08-26T13:24:43Z
dc.date.available.fl_str_mv 2019-08-26T13:24:43Z
dc.date.issued.fl_str_mv 2019
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv LEONEL, Caroline et al. Staphylococcus epidermidis role in the skin microenvironment. Journal of Cellular and Molecular Medicine, p. 1-7, 2019.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/35061
dc.identifier.issn.pt_BR.fl_str_mv 1582-1838
dc.identifier.doi.none.fl_str_mv 10.1111/jcmm.14415
identifier_str_mv LEONEL, Caroline et al. Staphylococcus epidermidis role in the skin microenvironment. Journal of Cellular and Molecular Medicine, p. 1-7, 2019.
1582-1838
10.1111/jcmm.14415
url https://www.arca.fiocruz.br/handle/icict/35061
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv John Wiley & Sons
publisher.none.fl_str_mv John Wiley & Sons
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/35061/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/35061/2/Staphylococcus%20epidermidis%20role%20in%20the%20skin%20microenvironment.pdf
https://www.arca.fiocruz.br/bitstream/icict/35061/3/Staphylococcus%20epidermidis%20role%20in%20the%20skin%20microenvironment.pdf.txt
bitstream.checksum.fl_str_mv 9193a7c197bc67acd023525e72a03240
a4a967ac59d2f92e0b7126436646ed19
212b0306580d4f0044d18f9a3edcc832
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
_version_ 1813009314378416128

Registros relacionados