Modulation of antibiotic resistance by the essential oil of Ocimum gratissimum L. in association with light-emitting diodes (LED) lights
| Autor(a) principal: | |
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| Data de Publicação: | 2020 |
| Outros Autores: | , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/47413 |
Resumo: | Centro Universitário Dr. Leão Sampaio (Unileão) |
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Leandro, Maria Karollyna do N. SilvaRocha, Janaína E.Bezerra, Camila F.Freitas, Priscilla R.Feitosa, Jessica Horana F.Bezerra, Viviane B.Barros, Rizelle de O.Leandro, Livia Maria G.Aguiar, José Junior dos S.Pereira, Paulo S.Christofoli, MarcelaRibeiro-Filho, JaimeIriti, MarcelloCoutinho, Henrique Douglas M.Matias, Edinardo Fagner F.2021-05-27T11:21:43Z2021-05-27T11:21:43Z2020LEANDRO, Maria Karollyna do N. Silva et al. Modulation of antibiotic resistance by the essential oil of Ocimum gratissimum L. in association with light-emitting diodes (LED) lights. Zeitschrift für Naturforschung C, v. 75, n. 11-12, p. 377-387, 6 July 2020.0939-5075https://www.arca.fiocruz.br/handle/icict/4741310.1515/znc-2020-00341865-7125Centro Universitário Dr. Leão Sampaio (Unileão)Universidade Regional do Cariri (URCA)Universidade Regional do Cariri. Laboratório de Microbiologia e Biologia Molecular. Crato, CE, Brasil / Centro Universitário Doutor Leão Sampaio. Juazeiro do Norte, CE, Brasil.Universidade Regional do Cariri. Laboratório de Microbiologia e Biologia Molecular. Crato, CE, Brasil.Universidade Regional do Cariri. Laboratório de Microbiologia e Biologia Molecular. Crato, CE, Brasil.Universidade Regional do Cariri. Laboratório de Microbiologia e Biologia Molecular. Crato, CE, Brasil.Centro Universitário Doutor Leão Sampaio. Juazeiro do Norte, CE, Brasil.Centro Universitário Doutor Leão Sampaio. Juazeiro do Norte, CE, Brasil.Centro Universitário Doutor Leão Sampaio. Juazeiro do Norte, CE, Brasil.Centro Universitário Doutor Leão Sampaio. Juazeiro do Norte, CE, Brasil.Centro Universitário Doutor Leão Sampaio. Juazeiro do Norte, CE, Brasil.Instituto Federal de Educação, Ciência e Tecnologia Goiano. Rio Verde, GO, Brasil.Universidade Federal de Goiás. Rede Centro Oeste de Pós-Graduação, Pesquisa e Inovação. Programa de Pós-Graduação em Biotecnologia e Biodiversidade. Goiânia, GO, Brasil.Fundação Oswaldo Cruz. Instituto de Gonçalo Moniz. Salvador, BA, Brasil.Milan State University. Department of Agricultural and Environmental Sciences. Milan, Italy.Universidade Regional do Cariri. Laboratório de Microbiologia e Biologia Molecular. Crato, CE, Brasil.Centro Caririense de Pós-Graduação. Juazeiro do Norte, CE, Brasil.This study aimed to evaluate the antibacterial and antibiotic-enhancing effects of the essential oil obtained from Ocimum gratissimum L. (OEOg) alone or in association with light-emitting diodes (LED) lights. The essential oil was obtained by hydrodistillation and its chemical composition analysed by gas chromatography coupled to mass spectrometry. The antibacterial and antibiotic-enhancing activities against multiresistant strains of Staphylococcus aureus and Escherichia coli were evaluated by the gaseous contact method. The analysis of the photoinductive effect on the antibacterial activity of the OEOg and antibiotics was assessed through exposure to different LED lights (red, blue and yellow). The phytochemical analysis identified five compounds, including eugenol, as the major constituent. The OEOg caused a significant inhibition of the halo, indicating a direct antibacterial effect. Exposure to the LED lights significantly enhanced the activity of the OEOg against E. coli. On the other hand, the action of the essential oil against S. aureus was enhanced by exposure to both blue and yellow lights. The effects of LED light exposure on the activity of conventional antibiotics varied significantly according to the drug and the bacterial strain. However, most combinations of LED lights and the OEOg presented synergistic effects against resistant bacterial strains, indicating enhanced antibacterial activity. Thus, these in vitro findings suggest that both OEOg and LED lights have promising antibacterial effects. Nevertheless, further research is required to evaluate in vivo the potential of these therapies for the treatment of infectious skin diseases.engDe GruyterResistência microbiana a medicamentosAtividade aprimorada de antibióticosLuzes LEDOcimum gratissimumStaphylococcus aureusBacterial resistanceEnhanced antibiotic activityLED lightsOcimum gratissimumModulation of antibiotic resistance by the essential oil of Ocimum gratissimum L. in association with light-emitting diodes (LED) lightsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83097https://www.arca.fiocruz.br/bitstream/icict/47413/1/license.txt36b51ef91c52b5338d9d29ba0cc807bcMD51ORIGINALSilva Leandro, Maria Karollyna do N. Modulation....pdfSilva Leandro, Maria Karollyna do N. 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| dc.title.en.fl_str_mv |
Modulation of antibiotic resistance by the essential oil of Ocimum gratissimum L. in association with light-emitting diodes (LED) lights |
| title |
Modulation of antibiotic resistance by the essential oil of Ocimum gratissimum L. in association with light-emitting diodes (LED) lights |
| spellingShingle |
Modulation of antibiotic resistance by the essential oil of Ocimum gratissimum L. in association with light-emitting diodes (LED) lights Leandro, Maria Karollyna do N. Silva Resistência microbiana a medicamentos Atividade aprimorada de antibióticos Luzes LED Ocimum gratissimum Staphylococcus aureus Bacterial resistance Enhanced antibiotic activity LED lights Ocimum gratissimum |
| title_short |
Modulation of antibiotic resistance by the essential oil of Ocimum gratissimum L. in association with light-emitting diodes (LED) lights |
| title_full |
Modulation of antibiotic resistance by the essential oil of Ocimum gratissimum L. in association with light-emitting diodes (LED) lights |
| title_fullStr |
Modulation of antibiotic resistance by the essential oil of Ocimum gratissimum L. in association with light-emitting diodes (LED) lights |
| title_full_unstemmed |
Modulation of antibiotic resistance by the essential oil of Ocimum gratissimum L. in association with light-emitting diodes (LED) lights |
| title_sort |
Modulation of antibiotic resistance by the essential oil of Ocimum gratissimum L. in association with light-emitting diodes (LED) lights |
| author |
Leandro, Maria Karollyna do N. Silva |
| author_facet |
Leandro, Maria Karollyna do N. Silva Rocha, Janaína E. Bezerra, Camila F. Freitas, Priscilla R. Feitosa, Jessica Horana F. Bezerra, Viviane B. Barros, Rizelle de O. Leandro, Livia Maria G. Aguiar, José Junior dos S. Pereira, Paulo S. Christofoli, Marcela Ribeiro-Filho, Jaime Iriti, Marcello Coutinho, Henrique Douglas M. Matias, Edinardo Fagner F. |
| author_role |
author |
| author2 |
Rocha, Janaína E. Bezerra, Camila F. Freitas, Priscilla R. Feitosa, Jessica Horana F. Bezerra, Viviane B. Barros, Rizelle de O. Leandro, Livia Maria G. Aguiar, José Junior dos S. Pereira, Paulo S. Christofoli, Marcela Ribeiro-Filho, Jaime Iriti, Marcello Coutinho, Henrique Douglas M. Matias, Edinardo Fagner F. |
| author2_role |
author author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Leandro, Maria Karollyna do N. Silva Rocha, Janaína E. Bezerra, Camila F. Freitas, Priscilla R. Feitosa, Jessica Horana F. Bezerra, Viviane B. Barros, Rizelle de O. Leandro, Livia Maria G. Aguiar, José Junior dos S. Pereira, Paulo S. Christofoli, Marcela Ribeiro-Filho, Jaime Iriti, Marcello Coutinho, Henrique Douglas M. Matias, Edinardo Fagner F. |
| dc.subject.other.pt_BR.fl_str_mv |
Resistência microbiana a medicamentos Atividade aprimorada de antibióticos Luzes LED Ocimum gratissimum Staphylococcus aureus |
| topic |
Resistência microbiana a medicamentos Atividade aprimorada de antibióticos Luzes LED Ocimum gratissimum Staphylococcus aureus Bacterial resistance Enhanced antibiotic activity LED lights Ocimum gratissimum |
| dc.subject.en.en.fl_str_mv |
Bacterial resistance Enhanced antibiotic activity LED lights Ocimum gratissimum |
| description |
Centro Universitário Dr. Leão Sampaio (Unileão) |
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2020 |
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2020 |
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2021-05-27T11:21:43Z |
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2021-05-27T11:21:43Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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LEANDRO, Maria Karollyna do N. Silva et al. Modulation of antibiotic resistance by the essential oil of Ocimum gratissimum L. in association with light-emitting diodes (LED) lights. Zeitschrift für Naturforschung C, v. 75, n. 11-12, p. 377-387, 6 July 2020. |
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https://www.arca.fiocruz.br/handle/icict/47413 |
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0939-5075 |
| dc.identifier.doi.pt_BR.fl_str_mv |
10.1515/znc-2020-0034 |
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1865-7125 |
| identifier_str_mv |
LEANDRO, Maria Karollyna do N. Silva et al. Modulation of antibiotic resistance by the essential oil of Ocimum gratissimum L. in association with light-emitting diodes (LED) lights. Zeitschrift für Naturforschung C, v. 75, n. 11-12, p. 377-387, 6 July 2020. 0939-5075 10.1515/znc-2020-0034 1865-7125 |
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De Gruyter |
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De Gruyter |
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