Limitations of Probiotic Therapy in Acute, Severe Dehydrating Diarrhea
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2003 |
| Outros Autores: | , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/26417 |
Resumo: | Ramos, Eduardo Antonio Gonçalves. “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”. |
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Ribeiro, Hugo CostaRibeiro, Tereza Cristina MedradoMattos, Angela Peixoto deValois, Sandra SNeri, Daniela AAlmeida, PatriciaCerqueira, Celina MRamos, Eduardo Antônio GonçalvesYoung, Rosemary JVanderhoof, Jon A2018-05-14T13:58:58Z2018-05-14T13:58:58Z2003RIBEIRO, H. C. et al. Limitations of Probiotic Therapy in Acute, Severe Dehydrating Diarrhea. Journal of Pediatric Gastroenterology and Nutrition, v. 36, p. 112–115, 2003.0277-2116https://www.arca.fiocruz.br/handle/icict/26417Ramos, Eduardo Antonio Gonçalves. “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”.Pronex/CNPq (661086/1998-4), BrazilFederal University of Bahia. School of Medicine. Department of Pediatrics. Salvador, BA, BrazilFederal University of Bahia. School of Medicine. Department of Pediatrics. Salvador, BA, BrazilFederal University of Bahia. School of Medicine. Department of Pediatrics. Salvador, BA, BrazilFederal University of Bahia. School of Medicine. Department of Pediatrics. Salvador, BA, BrazilFederal University of Bahia. School of Medicine. Department of Pediatrics. Salvador, BA, BrazilFederal University of Bahia. School of Medicine. Department of Pediatrics. Salvador, BA, BrazilFederal University of Bahia. School of Medicine. Department of Pediatrics. Salvador, BA, BrazilFederal University of Bahia. School of Medicine. Department of Pediatrics. Salvador, BA, BrazilUniversity of Nebraska Medical Center. Omaha, Nebraska, U.S.AUniversity of Nebraska Medical Center. Omaha, Nebraska, U.S.ABackground: Recent studies have shown that probiotics, most commonly Lactobacillus GG, may be useful in treating acute gastroenteritis. However, beneficial effects appear to be limited to a modest decrease in the duration of diarrhea. No studies have evaluated this therapy in moderate to severe dehydrating diarrhea in a metabolic facility. Methods: Male children less than 2 years of age were admitted to a metabolic unit of the Department of Pediatrics at the Federal University of Bahia, Brazil, with moderate dehydration and were randomized in a double-blind, placebo-controlled fashion. Oral rehydration solution (ORS) was administered per protocol and either placebo or Lactobacillus GG was given in combination with the ORS. Output of urine, stool, and vomitus was recorded along with stool weight, nude body weight, and standard laboratory assessments for hydration. Results: There was no significant reduction in diarrhea duration and stool output in the Lactobacillus GG group. However, Kaplan-Meier survival analysis demonstrated that, even in moderate to severe diarrhea, resolution of the illness occurred so rapidly, that statistically significant benefits of probiotic therapy could not be demonstrated. Conclusion: Our data implies that colonization must occur before benefits of probiotics can be realized. Probiotics are, therefore, likely to be of limited benefit in treating diarrheal illnesses of short duration such as viral enteritis. The beneficial effects of probiotics may be limited to prophylactic usage in high-risk populations.engLippincott, Williams & WilkinsDiarréiaProbióticosGastroenteriteDesidrataçãoLactobacillus GGHumanosDiarrheaProbioticsGastroenteritisDehydrationLactobacillus GGHumansLimitations of Probiotic Therapy in Acute, Severe Dehydrating Diarrheainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/26417/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALRamos EA Limitations of Probiotic Therapy in Acute.....pdfRamos EA Limitations of Probiotic Therapy in 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| dc.title.pt_BR.fl_str_mv |
Limitations of Probiotic Therapy in Acute, Severe Dehydrating Diarrhea |
| title |
Limitations of Probiotic Therapy in Acute, Severe Dehydrating Diarrhea |
| spellingShingle |
Limitations of Probiotic Therapy in Acute, Severe Dehydrating Diarrhea Ribeiro, Hugo Costa Diarréia Probióticos Gastroenterite Desidratação Lactobacillus GG Humanos Diarrhea Probiotics Gastroenteritis Dehydration Lactobacillus GG Humans |
| title_short |
Limitations of Probiotic Therapy in Acute, Severe Dehydrating Diarrhea |
| title_full |
Limitations of Probiotic Therapy in Acute, Severe Dehydrating Diarrhea |
| title_fullStr |
Limitations of Probiotic Therapy in Acute, Severe Dehydrating Diarrhea |
| title_full_unstemmed |
Limitations of Probiotic Therapy in Acute, Severe Dehydrating Diarrhea |
| title_sort |
Limitations of Probiotic Therapy in Acute, Severe Dehydrating Diarrhea |
| author |
Ribeiro, Hugo Costa |
| author_facet |
Ribeiro, Hugo Costa Ribeiro, Tereza Cristina Medrado Mattos, Angela Peixoto de Valois, Sandra S Neri, Daniela A Almeida, Patricia Cerqueira, Celina M Ramos, Eduardo Antônio Gonçalves Young, Rosemary J Vanderhoof, Jon A |
| author_role |
author |
| author2 |
Ribeiro, Tereza Cristina Medrado Mattos, Angela Peixoto de Valois, Sandra S Neri, Daniela A Almeida, Patricia Cerqueira, Celina M Ramos, Eduardo Antônio Gonçalves Young, Rosemary J Vanderhoof, Jon A |
| author2_role |
author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Ribeiro, Hugo Costa Ribeiro, Tereza Cristina Medrado Mattos, Angela Peixoto de Valois, Sandra S Neri, Daniela A Almeida, Patricia Cerqueira, Celina M Ramos, Eduardo Antônio Gonçalves Young, Rosemary J Vanderhoof, Jon A |
| dc.subject.other.pt_BR.fl_str_mv |
Diarréia Probióticos Gastroenterite Desidratação Lactobacillus GG Humanos |
| topic |
Diarréia Probióticos Gastroenterite Desidratação Lactobacillus GG Humanos Diarrhea Probiotics Gastroenteritis Dehydration Lactobacillus GG Humans |
| dc.subject.en.pt_BR.fl_str_mv |
Diarrhea Probiotics Gastroenteritis Dehydration Lactobacillus GG Humans |
| description |
Ramos, Eduardo Antonio Gonçalves. “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”. |
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2003 |
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2003 |
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2018-05-14T13:58:58Z |
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2018-05-14T13:58:58Z |
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RIBEIRO, H. C. et al. Limitations of Probiotic Therapy in Acute, Severe Dehydrating Diarrhea. Journal of Pediatric Gastroenterology and Nutrition, v. 36, p. 112–115, 2003. |
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https://www.arca.fiocruz.br/handle/icict/26417 |
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0277-2116 |
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RIBEIRO, H. C. et al. Limitations of Probiotic Therapy in Acute, Severe Dehydrating Diarrhea. Journal of Pediatric Gastroenterology and Nutrition, v. 36, p. 112–115, 2003. 0277-2116 |
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