Abnormal spontaneous interleukin 8 receptor expression: a brief report of two cases

Detalhes bibliográficos
Autor(a) principal: Antas, Paulo
Data de Publicação: 2012
Outros Autores: Holland, Steven, Sterling, Timothy
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/18688
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Clínica. Rio de Janeiro, RJ. Brasil / National Institute of Health. Laboratory of Clinical Infectious . Bethesda, MA, USA / Vanderbilt University School of Medicine. Department of Medicine. Division of Infectious Diseases. Nasville, TN, USA.
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spelling Antas, PauloHolland, StevenSterling, Timothy2017-04-27T15:15:40Z2017-04-27T15:15:40Z2012ANTAS, Paulo: HOLLAND, Steven: STERLING, Timothy. Abnormal spontaneous interleukin 8 receptor expression: a brief report of two cases. Revista da Sociedade Brasileira de Medicina Tropical, v.45, n.1, p.134-137, jan-fev, 2012.0037-8682https://www.arca.fiocruz.br/handle/icict/186881678-9849engSociedade Brasileira de Medicina TropicalInterleucina-8ReceptoresLinfócitosCitocinasInterleukin 8 receptorLymphocytesCytokinesAbnormal spontaneous interleukin 8 receptor expression: a brief report of two casesExpressão espontânea anômala do receptor de interleucina 8: um breve relato de dois casosinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Clínica. Rio de Janeiro, RJ. Brasil / National Institute of Health. Laboratory of Clinical Infectious . Bethesda, MA, USA / Vanderbilt University School of Medicine. Department of Medicine. Division of Infectious Diseases. Nasville, TN, USA.National Institutes of Health. Laboratory of Clinical Infectious Diseases. Bethesda, MA, USA.Vanderbilt University School of Medicine. Department of Medicine. Division of Infectious Diseases. Nasville, TN, USA. / Vanderbilt University School of Medicine. Department of Medicine. Center for Health Services Research. Nasville, TN, USA.Interleukin 8 (CXCL8) is an autocrine chemokine specific for the chemoattraction and activation of granulocytes, NKT cells and T lymphocytes. Patients with tuberculosis and latent Mycobacterium tuberculosis infection were assessed for the spontaneous expression of CXCR1 (CD128) and CXCR2 on lymphocytes and monocytes. Compared with ex vivo profiles, increased spontaneous CXCR2 expression and normal CXCR1 expression were found on lymphocytes in two out of 59 individuals. Monocytes showed normal ex vivo profiles for both receptors. After stimulation with purified protein derivative, the in vitro levels of CXCL8 were below the median levels of all patients with prior tuberculosis. Spontaneous CXCR2 modulation did not cause notable variation in the in vitro levels of CXCL8.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/18688/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALpaulorz_antas_etal_IOC_2012.pdfpaulorz_antas_etal_IOC_2012.pdfapplication/pdf735473https://www.arca.fiocruz.br/bitstream/icict/18688/2/paulorz_antas_etal_IOC_2012.pdfe91d3625a2cc8197c5efefa08d72d39aMD52TEXTpaulorz_antas_etal_IOC_2012.pdf.txtpaulorz_antas_etal_IOC_2012.pdf.txtExtracted texttext/plain18887https://www.arca.fiocruz.br/bitstream/icict/18688/3/paulorz_antas_etal_IOC_2012.pdf.txtd91969da969b473b8c104ae2f3dc62ccMD53icict/186882018-08-15 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dc.title.pt_BR.fl_str_mv Abnormal spontaneous interleukin 8 receptor expression: a brief report of two cases
dc.title.alternative.pt_BR.fl_str_mv Expressão espontânea anômala do receptor de interleucina 8: um breve relato de dois casos
title Abnormal spontaneous interleukin 8 receptor expression: a brief report of two cases
spellingShingle Abnormal spontaneous interleukin 8 receptor expression: a brief report of two cases
Antas, Paulo
Interleucina-8
Receptores
Linfócitos
Citocinas
Interleukin 8 receptor
Lymphocytes
Cytokines
title_short Abnormal spontaneous interleukin 8 receptor expression: a brief report of two cases
title_full Abnormal spontaneous interleukin 8 receptor expression: a brief report of two cases
title_fullStr Abnormal spontaneous interleukin 8 receptor expression: a brief report of two cases
title_full_unstemmed Abnormal spontaneous interleukin 8 receptor expression: a brief report of two cases
title_sort Abnormal spontaneous interleukin 8 receptor expression: a brief report of two cases
author Antas, Paulo
author_facet Antas, Paulo
Holland, Steven
Sterling, Timothy
author_role author
author2 Holland, Steven
Sterling, Timothy
author2_role author
author
dc.contributor.author.fl_str_mv Antas, Paulo
Holland, Steven
Sterling, Timothy
dc.subject.other.pt_BR.fl_str_mv Interleucina-8
Receptores
Linfócitos
Citocinas
topic Interleucina-8
Receptores
Linfócitos
Citocinas
Interleukin 8 receptor
Lymphocytes
Cytokines
dc.subject.en.pt_BR.fl_str_mv Interleukin 8 receptor
Lymphocytes
Cytokines
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunologia Clínica. Rio de Janeiro, RJ. Brasil / National Institute of Health. Laboratory of Clinical Infectious . Bethesda, MA, USA / Vanderbilt University School of Medicine. Department of Medicine. Division of Infectious Diseases. Nasville, TN, USA.
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2017-04-27T15:15:40Z
dc.date.available.fl_str_mv 2017-04-27T15:15:40Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv ANTAS, Paulo: HOLLAND, Steven: STERLING, Timothy. Abnormal spontaneous interleukin 8 receptor expression: a brief report of two cases. Revista da Sociedade Brasileira de Medicina Tropical, v.45, n.1, p.134-137, jan-fev, 2012.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/18688
dc.identifier.issn.pt_BR.fl_str_mv 0037-8682
dc.identifier.eissn.none.fl_str_mv 1678-9849
identifier_str_mv ANTAS, Paulo: HOLLAND, Steven: STERLING, Timothy. Abnormal spontaneous interleukin 8 receptor expression: a brief report of two cases. Revista da Sociedade Brasileira de Medicina Tropical, v.45, n.1, p.134-137, jan-fev, 2012.
0037-8682
1678-9849
url https://www.arca.fiocruz.br/handle/icict/18688
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical
publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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https://www.arca.fiocruz.br/bitstream/icict/18688/3/paulorz_antas_etal_IOC_2012.pdf.txt
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