Dengue Virus 2 American-Asian Genotype Identified during the 2006/2007 Outbreak in Piauı´, Brazil Reveals a Caribbean Route of Introduction and Dissemination of Dengue Virus in Brazil
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2014 |
| Outros Autores: | , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| DOI: | 10.1371/journal.pone.0104516 |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/9495 |
Resumo: | Universidade Federal de Minas Gerais. Departamento de Microbiologia. Belo Horizonte, MG, Brazil |
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Figueiredo, Leandra BarcelosSakamoto, TetsuCoelho, Luiz Felipe LeomilRocha, Eliseu Soares de OliveiraCota, Marcela Menezes GomesFerreira, Gustavo PortelaOliveira, Jaquelline Germano deKroon, Erna Geessien2015-02-13T12:51:43Z2015-02-13T12:51:43Z2014FIGUEIREDO, Leandra Barcelos. Dengue Virus 2 American-Asian Genotype Identified during the 2006/2007 Outbreak in Piauı, Brazil Reveals a Caribbean Route of Introduction and Dissemination of Dengue Virus in Brazil. PLoS ONE, v. 9, n. 8, p. e104516. 20141553-7366https://www.arca.fiocruz.br/handle/icict/949510.1371/journal.pone.0104516engPublic Library of ScienceDengue Virus 2 American-Asian Genotype Identified during the 2006/2007 Outbreak in Piauı´, Brazil Reveals a Caribbean Route of Introduction and Dissemination of Dengue Virus in Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal de Minas Gerais. Departamento de Microbiologia. Belo Horizonte, MG, BrazilUniversidade Federal de Minas Gerais. Laboratorio de Biodados. Belo Horizonte, MG, BrazilUniversidade Federal de Alfenas. Laboratorio de Vacinas. Alfenas, MG, BrazilUniversidade Federal de Minas Gerais. Laboratorio de Vırus. Belo Horizonte, MG, BrazilUniversidade Federal de Minas Gerais. Laboratorio de Vırus. Belo Horizonte, MG, BrazilUniversidade Federal do Piauı. Laboratorio de Biotecnologia. Parnaıba, PI, BrazilFundação Oswaldo Cruz. Centro de Pesquisa Rene Rachou. Laboratorio de Imunologia Celular e Molecular. Belo Horizonte, MG, BrazilUniversidade Federal de Minas Gerais. Instituto de Ciencias Biologicas. Departamento de Microbiologia. Laboratorio de Vırus. Belo Horizonte, MG, BrazilDengue virus (DENV) is the most widespread arthropod-borne virus, and the number and severity of outbreaks has increased worldwide in recent decades. Dengue is caused by DENV-1, DENV- 2, DENV-3 and DENV-4 which are genetically distant. The species has been subdivided into genotypes based on phylogenetic studies. DENV-2, which was isolated from dengue fever patients during an outbreak in Piaui, Brazil in 2006/2007 was analyzed by sequencing the envelope (E) gene. The results indicated a high similarity among the isolated viruses, as well as to other DENV-2 from Brazil, Central America and South America. A phylogenetic and phylogeographic analysis based on DENV-2E gene sequences revealed that these viruses are grouped together with viruses of the American-Asian genotype in two distinct lineages. Our results demonstrate the co-circulation of two American-Asian genotype lineages in northeast Brazil. Moreover, we reveal that DENV-2 lineage 2 was detected in Piauí before it disseminated to other Brazilian states and South American countries, indicating the existence of a new dissemination route that has not been previously described.Dengue vírusElisa PCRLANLHemorrhagic FeverVirus sequence databaseinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://www.arca.fiocruz.br/bitstream/icict/9495/1/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD51ORIGINAL2014_076.pdf2014_076.pdfapplication/pdf2045146https://www.arca.fiocruz.br/bitstream/icict/9495/2/2014_076.pdfadac382b643b6b8c3f83d425149347afMD52TEXT2014_076.pdf.txt2014_076.pdf.txtExtracted texttext/plain47940https://www.arca.fiocruz.br/bitstream/icict/9495/3/2014_076.pdf.txt5e630cf07e0579bbb203d8acd40e6e95MD53icict/94952019-06-19 10:07:38.439oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352019-06-19T13:07:38Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
| dc.title.pt_BR.fl_str_mv |
Dengue Virus 2 American-Asian Genotype Identified during the 2006/2007 Outbreak in Piauı´, Brazil Reveals a Caribbean Route of Introduction and Dissemination of Dengue Virus in Brazil |
| title |
Dengue Virus 2 American-Asian Genotype Identified during the 2006/2007 Outbreak in Piauı´, Brazil Reveals a Caribbean Route of Introduction and Dissemination of Dengue Virus in Brazil |
| spellingShingle |
Dengue Virus 2 American-Asian Genotype Identified during the 2006/2007 Outbreak in Piauı´, Brazil Reveals a Caribbean Route of Introduction and Dissemination of Dengue Virus in Brazil Figueiredo, Leandra Barcelos Dengue vírus Elisa PCR LANL Hemorrhagic Fever Virus sequence database |
| title_short |
Dengue Virus 2 American-Asian Genotype Identified during the 2006/2007 Outbreak in Piauı´, Brazil Reveals a Caribbean Route of Introduction and Dissemination of Dengue Virus in Brazil |
| title_full |
Dengue Virus 2 American-Asian Genotype Identified during the 2006/2007 Outbreak in Piauı´, Brazil Reveals a Caribbean Route of Introduction and Dissemination of Dengue Virus in Brazil |
| title_fullStr |
Dengue Virus 2 American-Asian Genotype Identified during the 2006/2007 Outbreak in Piauı´, Brazil Reveals a Caribbean Route of Introduction and Dissemination of Dengue Virus in Brazil |
| title_full_unstemmed |
Dengue Virus 2 American-Asian Genotype Identified during the 2006/2007 Outbreak in Piauı´, Brazil Reveals a Caribbean Route of Introduction and Dissemination of Dengue Virus in Brazil |
| title_sort |
Dengue Virus 2 American-Asian Genotype Identified during the 2006/2007 Outbreak in Piauı´, Brazil Reveals a Caribbean Route of Introduction and Dissemination of Dengue Virus in Brazil |
| author |
Figueiredo, Leandra Barcelos |
| author_facet |
Figueiredo, Leandra Barcelos Sakamoto, Tetsu Coelho, Luiz Felipe Leomil Rocha, Eliseu Soares de Oliveira Cota, Marcela Menezes Gomes Ferreira, Gustavo Portela Oliveira, Jaquelline Germano de Kroon, Erna Geessien |
| author_role |
author |
| author2 |
Sakamoto, Tetsu Coelho, Luiz Felipe Leomil Rocha, Eliseu Soares de Oliveira Cota, Marcela Menezes Gomes Ferreira, Gustavo Portela Oliveira, Jaquelline Germano de Kroon, Erna Geessien |
| author2_role |
author author author author author author author |
| dc.contributor.author.fl_str_mv |
Figueiredo, Leandra Barcelos Sakamoto, Tetsu Coelho, Luiz Felipe Leomil Rocha, Eliseu Soares de Oliveira Cota, Marcela Menezes Gomes Ferreira, Gustavo Portela Oliveira, Jaquelline Germano de Kroon, Erna Geessien |
| dc.subject.en.pt_BR.fl_str_mv |
Dengue vírus Elisa PCR LANL Hemorrhagic Fever Virus sequence database |
| topic |
Dengue vírus Elisa PCR LANL Hemorrhagic Fever Virus sequence database |
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Universidade Federal de Minas Gerais. Departamento de Microbiologia. Belo Horizonte, MG, Brazil |
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2014 |
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2014 |
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2015-02-13T12:51:43Z |
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2015-02-13T12:51:43Z |
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FIGUEIREDO, Leandra Barcelos. Dengue Virus 2 American-Asian Genotype Identified during the 2006/2007 Outbreak in Piauı, Brazil Reveals a Caribbean Route of Introduction and Dissemination of Dengue Virus in Brazil. PLoS ONE, v. 9, n. 8, p. e104516. 2014 |
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10.1371/journal.pone.0104516 |
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FIGUEIREDO, Leandra Barcelos. Dengue Virus 2 American-Asian Genotype Identified during the 2006/2007 Outbreak in Piauı, Brazil Reveals a Caribbean Route of Introduction and Dissemination of Dengue Virus in Brazil. PLoS ONE, v. 9, n. 8, p. e104516. 2014 1553-7366 10.1371/journal.pone.0104516 |
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