Clinical laboratory and dispersion pattern of COVID-19 in a family cluster in the social-distancing period

Detalhes bibliográficos
Autor(a) principal: Brito, Carlos Alexandre Antunes de
Data de Publicação: 2020
Outros Autores: Brito, Marina Coelho Moraes de, Martins, Thiago Henrique Fernandes, Brito, Cecília Coelho Moraes de, Albuquerque, Maria Fátima Militão, Brito, Rita de Cássia Coelho Moraes de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/43996
Resumo: Universidade Federal de Pernambuco. Hospital das Clínicas. Departamento de Medicina Interna. Recife, PE, Brasil / Instituto Autoimune de Pesquisa e Educação Continuada. Recife, PE, Brasil / Universidade Federal de Pernambuco. Centro de Ciências Médicas. Recife, PE, Brasil.
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spelling Brito, Carlos Alexandre Antunes deBrito, Marina Coelho Moraes deMartins, Thiago Henrique FernandesBrito, Cecília Coelho Moraes deAlbuquerque, Maria Fátima MilitãoBrito, Rita de Cássia Coelho Moraes de2020-10-15T14:40:00Z2020-10-15T14:40:00Z2020BRITO, Carlos Alexandre Antunes de et al. Clinical laboratory and dispersion pattern of COVID-19 in a family cluster in the social-distancing period. The Journal of Infection in Developing Countries, v. 14, n. 9, p. 987-993, 30 Set. 2020.1972-2680https://www.arca.fiocruz.br/handle/icict/4399610.3855/jidc.13580engThe Journal of Infection in Developing CountriesClinical laboratory and dispersion pattern of COVID-19 in a family cluster in the social-distancing periodinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal de Pernambuco. Hospital das Clínicas. Departamento de Medicina Interna. Recife, PE, Brasil / Instituto Autoimune de Pesquisa e Educação Continuada. Recife, PE, Brasil / Universidade Federal de Pernambuco. Centro de Ciências Médicas. Recife, PE, Brasil.Instituto Autoimune de Pesquisa e Educação Continuada. Recife, PE, Brasil / Universidade Federal de Pernambuco. Centro de Ciências Médicas. Recife, PE, Brasil.Instituto Autoimune de Pesquisa e Educação Continuada. Recife, PE, Brasil / Universidade Federal de Pernambuco. Centro de Ciências Médicas. Recife, PE, Brasil.Instituto Autoimune de Pesquisa e Educação Continuada. Recife, PE, Brasil / Instituto de Medicina Integral Professor Fernando Figueira. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.Instituto Autoimune de Pesquisa e Educação Continuada. Recife, PE, Brasil / Instituto de Medicina Integral Professor Fernando Figueira. Recife, PE, Brasil / Universidade de Pernambuco. Faculdade de Ciências Médicas. Recife, PE, Brasil.Introduction: Since the first reports of coronavirus disease 2019 (COVID-19) in December 2019, the disease has spread worldwide. Different social isolation strategies have been adopted to reduce community transmission, but few studies have evaluated the pattern of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection in a family cluster during periods of isolation. We report an outbreak in 24 members of a family cluster during a period of social distancing. Methodology: We carried out an observational descriptive study of a family cluster infected with SARS-CoV-2 in Pernambuco, Northeast Brazil. Laboratory confirmation included RT-PCR of nasopharyngeal samples or IgM or IgG serology. Results: The attack rates were 75% (19/24) based on laboratory-confirmed cases and 87.5% (21/24) including probable cases. The time of spread was 17 days from the first case. All patients had mild symptoms, requiring no hospitalization, and none of them died. The frequency of symptomatic, laboratory-confirmed patients was higher among adults (94%) than among children (50%); the paediatric age group also had a higher frequency of exposed individuals who remained negative for infection. Ground-glass opacities on chest computed tomography were present in all patients with reported dyspnoea. Conclusion: This study highlights a high risk of intrahousehold transmission from an index case, suggesting the need for (I) specific guidelines during periods of social distancing, (II) minimization of external exposures and, above all, (III) adoption of strict quarantine measures for suspected cases and family members to prevent outbreaks from spreading.COVID-19ClusterDispersionSocial distancinginfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; 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dc.title.en.fl_str_mv Clinical laboratory and dispersion pattern of COVID-19 in a family cluster in the social-distancing period
title Clinical laboratory and dispersion pattern of COVID-19 in a family cluster in the social-distancing period
spellingShingle Clinical laboratory and dispersion pattern of COVID-19 in a family cluster in the social-distancing period
Brito, Carlos Alexandre Antunes de
COVID-19
Cluster
Dispersion
Social distancing
title_short Clinical laboratory and dispersion pattern of COVID-19 in a family cluster in the social-distancing period
title_full Clinical laboratory and dispersion pattern of COVID-19 in a family cluster in the social-distancing period
title_fullStr Clinical laboratory and dispersion pattern of COVID-19 in a family cluster in the social-distancing period
title_full_unstemmed Clinical laboratory and dispersion pattern of COVID-19 in a family cluster in the social-distancing period
title_sort Clinical laboratory and dispersion pattern of COVID-19 in a family cluster in the social-distancing period
author Brito, Carlos Alexandre Antunes de
author_facet Brito, Carlos Alexandre Antunes de
Brito, Marina Coelho Moraes de
Martins, Thiago Henrique Fernandes
Brito, Cecília Coelho Moraes de
Albuquerque, Maria Fátima Militão
Brito, Rita de Cássia Coelho Moraes de
author_role author
author2 Brito, Marina Coelho Moraes de
Martins, Thiago Henrique Fernandes
Brito, Cecília Coelho Moraes de
Albuquerque, Maria Fátima Militão
Brito, Rita de Cássia Coelho Moraes de
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Brito, Carlos Alexandre Antunes de
Brito, Marina Coelho Moraes de
Martins, Thiago Henrique Fernandes
Brito, Cecília Coelho Moraes de
Albuquerque, Maria Fátima Militão
Brito, Rita de Cássia Coelho Moraes de
dc.subject.en.en.fl_str_mv COVID-19
Cluster
Dispersion
Social distancing
topic COVID-19
Cluster
Dispersion
Social distancing
description Universidade Federal de Pernambuco. Hospital das Clínicas. Departamento de Medicina Interna. Recife, PE, Brasil / Instituto Autoimune de Pesquisa e Educação Continuada. Recife, PE, Brasil / Universidade Federal de Pernambuco. Centro de Ciências Médicas. Recife, PE, Brasil.
publishDate 2020
dc.date.accessioned.fl_str_mv 2020-10-15T14:40:00Z
dc.date.available.fl_str_mv 2020-10-15T14:40:00Z
dc.date.issued.fl_str_mv 2020
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv BRITO, Carlos Alexandre Antunes de et al. Clinical laboratory and dispersion pattern of COVID-19 in a family cluster in the social-distancing period. The Journal of Infection in Developing Countries, v. 14, n. 9, p. 987-993, 30 Set. 2020.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/43996
dc.identifier.issn.pt_BR.fl_str_mv 1972-2680
dc.identifier.doi.pt_BR.fl_str_mv 10.3855/jidc.13580
identifier_str_mv BRITO, Carlos Alexandre Antunes de et al. Clinical laboratory and dispersion pattern of COVID-19 in a family cluster in the social-distancing period. The Journal of Infection in Developing Countries, v. 14, n. 9, p. 987-993, 30 Set. 2020.
1972-2680
10.3855/jidc.13580
url https://www.arca.fiocruz.br/handle/icict/43996
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv The Journal of Infection in Developing Countries
publisher.none.fl_str_mv The Journal of Infection in Developing Countries
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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https://www.arca.fiocruz.br/bitstream/icict/43996/2/Brito_Carlos_Alexandre_etal_IAMG_2020_COVID-19.pdf
https://www.arca.fiocruz.br/bitstream/icict/43996/3/Brito_Carlos_Alexandre_etal_IAMG_2020_COVID-19.pdf.txt
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